Evaluation of a clinical dose accumulation algorithm using deformable gel dosimetry

Matrosic, C; Holmes, S; Bednarz, Bryan; Culberson, Wesley S.

doi:10.1088/1742-6596/1305/1/012002

Cited by 6 publications

(4 citation statements)

References 7 publications

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“…DIR is implemented in some commercial solutions (ProSoma Core, Adaptivo) to propagate contours and density information from the planning CT to the geometry of the CBCT, allowing a daily dose estimation and the production of daily and cumulative dose-volume histograms (Matrosic et al 2019).…”

Section: Deformable Registrationmentioning

confidence: 99%

IPEM topical report: guidance for the clinical implementation of online treatment monitoring solutions for IMRT/VMAT

Stevens

Moloney

Blackmore³

et al. 2023

Phys. Med. Biol.

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This report provides guidance for the implementation of online treatment monitoring (OTM) solutions in radiotherapy (RT), with a focus on modulated treatments. Support is provided covering the implementation process, from identification of an OTM solution to local implementation strategy. Guidance has been developed by a RT special interest group (RTSIG) working party (WP) on behalf of the Institute of Physics and Engineering in Medicine (IPEM). Recommendations within the report are derived from the experience of the WP members (in consultation with manufacturers, vendors and user groups), existing guidance or legislation and a UK survey conducted in 2020 (Stevens et al., 2021).OTM is an inclusive term representing any system capable of providing a direct or inferred measurement of the delivered dose to a RT patient. Information on each type of OTM is provided but, commensurate with UK demand, guidance is largely influenced by in vivo dosimetry (IVD) methods utilising the electronic portal imager device (EPID).Sections are included on the choice of OTM solutions, acceptance and commissioning methods with recommendations on routine quality control, analytical methods and tolerance setting, clinical introduction and staffing/resource requirements. The guidance aims to give a practical solution to sensitivity and specificity testing. Functionality is provided for the user to introduce known errors into treatment plans for local testing. Receiver operating characteristic (ROC) analysis is discussed as a tool to performance assess OTM systems. OTM solutions can help verify the correct delivery of radiotherapy treatment. Furthermore, modern systems are increasingly capable of providing clinical decision-making information which can impact the course of a patient’s treatment. However, technical limitations persist. It is not within the scope of this guidance to critique each available solution, but the user is encouraged to carefully consider workflow and engage with manufacturers in resolving compatibility issues. 

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Section: Deformable Registrationmentioning

confidence: 99%

IPEM topical report: guidance for the clinical implementation of online treatment monitoring solutions for IMRT/VMAT

Stevens

Moloney

Blackmore³

et al. 2023

Phys. Med. Biol.

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“…For this study, a head phantom was manufactured by RTsafe (RTsafe, Athens, Greece) using the CT images of the patient to produce a patient-customized phantom [13] polymer gel, which is a water-equivalent material that enables a 3D dose evaluation (Fig. 1).…”

Section: Producing the Gel Phantom With 3d Printingmentioning

confidence: 99%

“…Lee et al [12] performed a 3D dosimetry with the polymer-gel located inside the insert of a liver cancer model made with a 3D printer during SBRT treatment; they were unable to conduct a dose evaluation in the environment that resembles the insides of the human body since only the liver was printed in 3D and inserted into a single-material phantom. Matrosic et al [13] evaluated a 3D dose distribution by irradiating a therapeutic dose to a phantom coated with a polymer gel; this was conducted using a commercially available plastic phantom and not a material that mimics the human body.…”

Section: Introductionmentioning

confidence: 99%

Dosimetric Study Using Patient-Specific Three-Dimensional-Printed Head Phantom with Polymer Gel in Radiation Therapy

Choi

Kim

et al. 2021

Progress in Medical Physics

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In this study, we aimed to manufacture a patient-specific gel phantom combining threedimensional (3D) printing and polymer gel and evaluate the radiation dose and dose profile using gel dosimetry. Methods:The patient-specific head phantom was manufactured based on the patient's computed tomography (CT) scan data to create an anatomically replicated phantom; this was then produced using a ColorJet 3D printer. A 3D polymer gel dosimeter called RTgel-100 is contained inside the 3D printing head phantom, and irradiation was performed using a 6 MV LINAC (Varian Clinac) X-ray beam, a linear accelerator for treatment. The irradiated phantom was scanned using magnetic resonance imaging (Siemens) with a magnetic field of 3 Tesla (3T) of the Korea Institute of Nuclear Medicine, and then compared the irradiated head phantom with the dose calculated by the patient's treatment planning system (TPS). Results:The comparison between the Hounsfield unit (HU) values of the CT image of the patient and those of the phantom revealed that they were almost similar. The electron density value of the patient's bone and brain was 996±167 HU and 58±15 HU, respectively, and that of the head phantom bone and brain material was 986±25 HU and 45±17 HU, respectively. The comparison of the data of TPS and 3D gel revealed that the difference in gamma index was 2%/2 mm and the passing rate was within 95%.Conclusions: 3D printing allows us to manufacture variable density phantoms for patient-specific dosimetric quality assurance (DQA), develop a customized body phantom of the patient in the future, and perform a patient-specific dosimetry with film, ion chamber, gel, and so on.

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“…Dose calculations are performed using a reference dose perturbation algorithm with 3D dose calculation on CBCT. Output DVH analysis(Matrosic et al 2019).…”

mentioning

confidence: 99%

IPEM topical report: results of a 2020 UK survey on the use of online treatment monitoring solutions for IMRT/VMAT

Stevens

Moloney²,

Bangiri

et al. 2021

Phys. Med. Biol.

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Numerous commercial technologies for online treatment monitoring (OTM) in radiotherapy (RT) are currently available including electronic portal imaging device (EPID) in vivo dosimetry (IVD), transmission detectors and log files analysis. Despite this, in the UK there exists limited guidance on how to implement and commission a system for clinical use or information about the resources required to set up and maintain a service. A Radiotherapy Special Interest Group working party, established by Institute of Physics and Engineering in Medicine was formed with a view to reassess the current practice for OTM in the UK and an aim to develop consensus guidelines for the implementation of a system. A survey distributed to Heads of Medical Physics at 71 UK RT departments investigated: availability of OTM in the UK; estimates of workload; clinical implementation; methods of analysis; quality assurance; and opinions on future directions. The survey achieved a 76% response rate and demonstrated that OTM is widely supported in the UK, with 87% of respondents indicating all patients should undergo OTM. EPID IVD (EIVD) was the most popular form of OTM. An active EIVD service was reported by 37% of respondents, with 84% believing it was the optimal solution. This demonstrates a steady increase in adoption since 2012. Other forms of OTM were in use but they had only been adopted by a minority of centres. Financial barriers and the increase of staff workload continue to hinder wider implementation in other centres. Device automation and integration is a key factor for successful future adoption and requires support between treatment machine and OTM manufacturers. The survey has provided an updated analysis on the use of OTM methods across the UK. Future guidance is recommended on commissioning, adoption of local tolerances and root-cause analysis strategies to assist departments intending to implement OTM.

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Evaluation of a clinical dose accumulation algorithm using deformable gel dosimetry

Cited by 6 publications

References 7 publications

IPEM topical report: guidance for the clinical implementation of online treatment monitoring solutions for IMRT/VMAT

IPEM topical report: guidance for the clinical implementation of online treatment monitoring solutions for IMRT/VMAT

Dosimetric Study Using Patient-Specific Three-Dimensional-Printed Head Phantom with Polymer Gel in Radiation Therapy

IPEM topical report: results of a 2020 UK survey on the use of online treatment monitoring solutions for IMRT/VMAT

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