Evaluation of a clinically practical, ERP-based neurometric battery: Application to age-related changes in brain function

Kieffaber, Paul D.; Okhravi, Hamid; Hershaw, Jamie; Cunningham, Emily

doi:10.1016/j.clinph.2016.01.023

Cited by 9 publications

(2 citation statements)

References 26 publications

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“…Recent studies have seen progress in utilizing both non-biofluid–based and biofluid-based biomarkers to assist with POCD evaluation, in addition to neuropsychological assessments. One previous study has revealed that event-related potentials, which marks electrophysiological components, is capable of differentiating cognitive functions between older and younger adults, 79 and has been utilized as a marker for cognition when comparing POCD incidence between intravenous and inhalation anaesthesia. 23 In another study, 6-min walk distance measured before surgery has been shown to be lower in those who developed POCD.…”

Section: Risk Assessment For Pocdmentioning

confidence: 99%

Identification of individuals at risk for postoperative cognitive dysfunction (POCD)

Yang

Huang

et al. 2022

Ther Adv Neurol Disord

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Postoperative cognitive dysfunction (POCD) is common, occurring in around 10-54% of individuals within first few weeks after surgery. Although the majority of POCD is less commonly persistent later than 3 months following surgery, the condition increases length of stay (LOS), mortality and long-term cognitive decline, raising the need for a broad screening to identify individuals at risk for POCD during the perioperative period. In this narrative review, we summarize preoperative, intraoperative and postoperative risk factors for POCD reported in last 5 years and discuss neuropsychological tools and potential biomarkers and time points for assessment that might be suitable for clinical use. We aim to provide crucial information for developing a strategy of routine screening for POCD, which may assist with better identification of at-risk individuals for early interventions. Very importantly, the utilization of a standardized strategy may also allow higher consistency and comparability across different studies.

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Section: Risk Assessment For Pocdmentioning

confidence: 99%

Identification of individuals at risk for postoperative cognitive dysfunction (POCD)

Yang

Huang

et al. 2022

Ther Adv Neurol Disord

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“…If popular, we hope to include a multitude of task types in the future, such as reward gambling, stop-signal, basic language, and motor tasks, etc. Some existing task batteries for EEG assessment capitalize on simultaneous acquisition of a large number of EEG events/ERP components ( Kappenman and Luck, 2012 ; Kieffaber et al, 2016 ; Nair et al, 2016 ); this may be a promising direction for future expansion.…”

Section: Pred+ctmentioning

confidence: 99%

The Patient Repository for EEG Data + Computational Tools (PRED+CT)

Cavanagh

Napolitano

et al. 2017

Front. Neuroinform.

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Electroencephalographic (EEG) recordings are thought to reflect the network-wide operations of canonical neural computations, making them a uniquely insightful measure of brain function. As evidence of these virtues, numerous candidate biomarkers of different psychiatric and neurological diseases have been advanced. Presumably, we would only need to apply powerful machine-learning methods to validate these ideas and provide novel clinical tools. Yet, the reality of this advancement is more complex: the scale of data required for robust and reliable identification of a clinical biomarker transcends the ability of any single laboratory. To surmount this logistical hurdle, collective action and transparent methods are required. Here we introduce the Patient Repository of EEG Data + Computational Tools (PRED+CT: predictsite.com). The ultimate goal of this project is to host a multitude of available tasks, patient datasets, and analytic tools, facilitating large-scale data mining. We hope that successful completion of this aim will lead to the development of novel EEG biomarkers for differentiating populations of neurological and psychiatric disorders.

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