“…In the femur with prosthesis the loads are fundamentally transmitted from the prosthetic head to its stem, producing the stress-shielding and loading the femur in the zones corresponding to the HA end, producing bottleneck effect. These changes explain that with first generation cemented stems the losses in density reached up to 45% (Sychter and Engh, 1996;McAuley et al, 2000;Sychter et al, 2002), with second generation stems still reaching between 20% and 25% at the end of the first or second year (Ka¨rrholm et al, 2002) and with tapered stems decreases between 10% and 30% were found with proximal predominance (Gibbons et al, 2001;Schmidt et al, 2004). Custom made implants had decreases in proximal areas of 10-15% at the end of the first year (Zerahn et al, 1998;Martini et al, 2000); femoral stems with reduced stiffness showed 15% reduction in the calcar at the end of the second year (Ka¨rrholm et al, 2002;Nagi et al, 2006).…”