1990
DOI: 10.1097/00007435-199004000-00008
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Evaluation of a Genus-specific Monoclonal Antibody in an Amplified Enzyme-linked Immunoassay in the Detection of Chlamydia in Urine Samples from Men

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Cited by 20 publications
(9 citation statements)
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“…In the present study, IDEIA 111 showed a sensitivity of 42% in the detection of Chlamydia antigens in urine sediments obtained from asymptomatic men. This is similar to the results of Jawadet al (7). When studying urine samples collected from patients attending an STD clinic, they found IDEIA I11 significantly less sensitive in asymptomatic men than in men with clinical evidence of urethritis (59Y0 vs 80%).…”
Section: Discussionsupporting
confidence: 88%
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“…In the present study, IDEIA 111 showed a sensitivity of 42% in the detection of Chlamydia antigens in urine sediments obtained from asymptomatic men. This is similar to the results of Jawadet al (7). When studying urine samples collected from patients attending an STD clinic, they found IDEIA I11 significantly less sensitive in asymptomatic men than in men with clinical evidence of urethritis (59Y0 vs 80%).…”
Section: Discussionsupporting
confidence: 88%
“…Although these methods are reasonable sensitive (75% to 95%), they require additional specific diagnostic procedures in order to establish a definitive etiological diagnosis. Other investigators have tried to isolate C. trachomatis directly from first-void urine sediments, though without much success (2,7). More recently, detection of Chlamydia antigens in urine by EIA had been shown to be useful for the diagnosis of urethral chlamydial infections in males (2, 6, 7, 14).…”
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confidence: 99%
“…Detection of chlamydial antigen in sediments of first-void urine (FVU) from men is a feasible and accurate test for chlamydial urethritis (5,13,20). The use of FVU, especially for asymptomatic carriers, is more acceptable to males than urethral swabbing (4).…”
mentioning
confidence: 99%
“…Because urethral swabs are painful and 10 to 30% of swabs are inadequately obtained, a noninvasive collection procedure, such as urine testing, would be particularly valuable for screening men for infection (3,9,26). In previous studies, urine testing using enzyme immunoassay or direct fluorescent antibody to detect C. trachomatis antigen have shown various degrees of sensitivity, sometimes as low as 45% (3,4,8,11,15,26,27). Since the amplification component of the polymerase chain reaction (PCR) assay (17) should increase the sensitivity of urine testing, we compared a PCR method that detects C. trachomatis DNA in urine with standard urethral cultures as a means for diagnosing C. trachomatis urethritis.…”
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confidence: 99%