Evaluation of a mobile phone-based, advanced symptom management system (ASyMS©) in the management of chemotherapy-related toxicity

Abstract

ABSTRACT:Objectives: To evaluate the impact of a mobile phone based, remote monitoring, advanced symptom management system (ASyMS © ) on the incidence, severity and distress of six chemotherapy related symptoms (nausea, vomiting, fatigue, mucositis, hand foot syndrome, diarrhoea) in patients with lung, breast or colorectal cancer. Main outcome measures:Chemotherapy related morbidity of six common chemotherapy related symptoms (nausea, vomiting, fatigue, mucositis, hand foot syndrome and diarhhoea)Results: There were significantly higher reports of fatigue in the control group compared to the intervention group (odds ratio 2.29, 95% CI 1.04 to 5.05, P=0.040) and reports of hand foot syndrome were on average lower in the control group (odds ratio control: intervention, 0.39, 95% CI to 0.92, P=0.031).

Trajectories and predictors of state and trait anxiety in patients receiving chemotherapy for breast and colorectal cancer: Results from a longitudinal study

“…The overall aim of the study was to examine the feasibility and acceptability of the use of the Advanced Symptom Management System (ASyMS), a mobile phone-based, real-time, remote patientmonitoring system to assist with the assessment and management of chemotherapy-related toxicity (Kearney et al, 2009). …”

Mobile Breast Cancer e-Support Program for Chinese Women With Breast Cancer Undergoing Chemotherapy (Part 2): Multicenter Randomized Controlled Trial (Preprint)

“…A sample of 108 participants (54 participants per group) was needed to detect an effect size of at least 0.60, with 80% power, two-sided P<.05, and 20% attrition. A dropout rate of 10-20% were reported in previous studies involving an app-based study [9,24]. Finally, the recruitment numbered 114 participants in total (57 participants per group).…”

“…However, there remains a paucity of randomized controlled trials (RCTs) to evaluate the effectiveness of app-based programs targeting women with breast cancer undergoing chemotherapy [7]. To date, most app-based programs including women with breast cancer have not been chemotherapy specific [8], or breast cancer specific [9]. Furthermore, women's usage of eHealth interventions and their relationship with effectiveness has rarely been reported in trials [10].…”

Rational development of telehealth to support primary care respiratory medicine: patient distribution and organisational factors

“…Current use of telehealth technologies in respiratory medicine is limited; 2 evidence for their effective use is accruing, [8][9][10][11][12][13][14][15][16][17][18][19] but there remain concerns about clinical and cost effectiveness. 7,17 These issues will be affected by the setting in which telehealth is deployed.…”

“…13,14 Remote monitoring of chemotherapy by mobile phone has also proven successful in lung cancer management. 15 In a systematic review of telehealth applications, patient acceptance and satisfaction were generally high, although robust evidence on cost effectiveness and benefits was lacking. 16 For asthma, a more recent systematic review of randomised controlled trials of telehealthcare highlighted the importance of disease severity in determining effectiveness -clinical benefit being more likely in those at greater risk of hospital admission.…”