Evaluation of a MPB70-ELISA to differentiate Mycobacterium bovis from M. avium-sensitized swine

Evaluación de anticuerpos frente a tres bacterias zoonóticas y factores de riesgo asociados en explotaciones porcinas de Colombia

“…Despite the small number of epidemiological studies of M. bovis in pig farming, intradermal tests have been used as a diagnostic method, although they lack objective patterns of interpretation that are independent of the antigen used (27). With regard to serological tests, while suppliers claim good sensitivity and specificity, some studies report low sensitivity, especially in young pigs (12), which could explain why this study detected positivity only in adult pigs (females and males).…”

“…Although microbiological culture is the reference method for determining the presence of these pathogenic bacteria, antibody titre determination by serology can be used as a screening tool, which makes it possible to determine the exposure of pigs to the pathogen and to implement epidemiological surveillance programmes, as well as being quick and economical (12,25,26). While it may be somewhat lacking in specificity, if performed in conjunction with microbiological methods it supports the final diagnosis (27). It also makes it possible to determine the degree of increase and/or reduction in prevalence, data that can be used to establish prevention and control measures within production establishments, applying the herd health concept (28).…”