Evaluation of a novel gel-based ureteral stent with biofilm-resistant characteristics

Rosman, Brian M.; Barbosa, João Arthur Brunhara Alves; Passerotti, Carlo P.; Cendron, Marc; Nguyen, Hiep T.

doi:10.1007/s11255-013-0636-3

Cited by 17 publications

(9 citation statements)

References 27 publications

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“…Although a reduction of biofilm formation has been reported for other different stent coatings in vitro 48,49,50 and in vivo, 51 our literature search revealed no clinical studies investigating the potential of such coatings to reduce SRS.…”

Section: Stent Coatingsmentioning

confidence: 84%

Prevention and treatment of symptoms associated with indwelling ureteral stents: A systematic review

et al. 2017

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Temporary drainage of the upper urinary tract by internal ureteral stents is a routine procedure in endourology. However, it is associated with a clear side-effect profile. Our aim was to evaluate prevention and treatment options of stent-related symptoms. We carried out a systematic review according to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines using MEDLINE and SCOPUS, and identified 107 appropriate records. A high number of these studies showed clear methodological limitations. Available data clearly support the use of a 1 -blockers in patients suffering from stent-related symptoms. It seems that antimuscarinic monotherapy or combination with a 1 -blockers might also play an important role, whereas the use of classical analgesics in the treatment of stent-related symptoms has not been assessed systematically within clinical trials so far. Improvements in stent design and material seem to have the potential to reduce stent-related symptoms. However, so far there is no type of stent with outstanding characteristics and clear evidence suggesting fundamental advantages compared with a standard double pigtail stent. Although stent diameter does not seem to influence patients' comfort, it seems to be beneficial to choose a proper stent-length. Coated and drug-eluting stents, as well as intravesical drug application, seem to be promising concepts to prevent stent-related symptoms, but still have to be considered as experimental approaches. Furthermore, thorough patient education has the potential to reduce the morbidity associated with ureteral stenting. Further research in the field seems to be mandatory.

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Section: Stent Coatingsmentioning

confidence: 84%

Prevention and treatment of symptoms associated with indwelling ureteral stents: A systematic review

et al. 2017

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“…These EPS and cell debris can also cover the antimicrobial surfaces, increasing bacterial attachment and shielding the bacteria. In some studies, small percentages of serum are added to the medium, which is a step in the right direction [13].…”

Section: How Close To Reality Can a Biofilm Model Be?mentioning

confidence: 99%

In Vitro Biofilm Models for Device-Related Infections

Buhmann

Stiefel

Maniura‐Weber

et al. 2016

Trends in Biotechnology

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“…Metallic stents represent a good alternative. Different types of metallic stents exist: non-expandable coiled metallic Resonance stent (Cook Medical, Bloomington, IN, USA), thermo-expandable metal alloy Memokath 051 stent (PNN Medical, Glostrup, Denmark), and self-expandable covered metallic UVENTA stent (Taewoong Medical, Gojeong-ro, Wolgot-myeon, Gimposi, Gyeonggi-do, South Korea) [28].…”

Section: Gel-based Stentmentioning

confidence: 99%

Ureteral JJ Stent � Which One is Better?

Spînu¹,

Marcu²,

Socea³

et al. 2018

Rev. Chim.

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Ureteral stents represent a minimally invasive alternative to preserve urinary drainage whenever the ureter is damaged or is under a significant risk to be occluded due to extrinsic or intrinsic etiology, even due to iatrogenic cause. Ureteral obstruction caused by extrinsic compression is often associated with intra-abdominal neoplasms. The first-line therapy to relieve such obstructions is usually internal drainage with ureteral stents. Ureteral stents made of different materials have been designed to achieve the best drainage possible. In this study, we tried to compare different JJ stent materials � which are better and their pros and cons. The ideal stent that would combine perfect long-term efficacy with no stent-related morbidity is still lacking and stent usage is associated with several adverse effects that limit its value as a tool for long-term urinary drainage. Several new ideas on stent design, composition material and stent coating are currently under evaluation, and are trying to eliminate the drawbacks of ureteral stent usage. Almost every clinician is familiar with the drawbacks that are associated with stents, including infection, encrustation, pain and discomfort.

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Evaluation of a novel gel-based ureteral stent with biofilm-resistant characteristics

Abstract: In this study, the gel-based stent shows a demonstrable reduction in bacterial counts and biofilm formation. The use of the pAMS may reduce the risk of infection associated with stent usage.

Cited by 17 publications

References 27 publications

Prevention and treatment of symptoms associated with indwelling ureteral stents: A systematic review

Prevention and treatment of symptoms associated with indwelling ureteral stents: A systematic review

In Vitro Biofilm Models for Device-Related Infections

Ureteral JJ Stent � Which One is Better?

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