Evaluation of a numerical simulation for cryoablation – comparison with bench data, clinical kidney and lung cases

Rieder, Christian; Schwenke, Michael; Pätz, Torben; Georgii, Joachim; Ballhausen, Hanne; Schwen, Lars Ole; Haase, Sabrina; Preußer, Tobias

doi:10.1080/02656736.2020.1845402

Cited by 10 publications

(6 citation statements)

References 32 publications

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“…Performance metrics at the aggregated data level (Fig. 3 ) compares very well with reported values from validation studies in literature 11 , 13 , 15 using RFA or cryoablation: Dice coefficient close to and absolute Hausdorff distance ranging between and mm.…”

Section: Discussionsupporting

confidence: 77%

First validation of a model-based hepatic percutaneous microwave ablation planning on a clinical dataset

Frackowiak,

Van den Bosch,

Tokoutsi

et al. 2023

Sci Rep

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A model-based planning tool, integrated in an imaging system, is envisioned for CT-guided percutaneous microwave ablation. This study aims to evaluate the biophysical model performance, by comparing its prediction retrospectively with the actual ablation ground truth from a clinical dataset in liver. The biophysical model uses a simplified formulation of heat deposition on the applicator and a heat sink related to vasculature to solve the bioheat equation. A performance metric is defined to assess how the planned ablation overlaps the actual ground truth. Results demonstrate superiority of this model prediction compared to manufacturer tabulated data and a significant influence of the vasculature cooling effect. Nevertheless, vasculature shortage due to branches occlusion and applicator misalignment due to registration error between scans affects the thermal prediction. With a more accurate vasculature segmentation, occlusion risk can be estimated, whereas branches can be used as liver landmarks to improve the registration accuracy. Overall, this study emphasizes the benefit of a model-based thermal ablation solution in better planning the ablation procedures. Contrast and registration protocols must be adapted to facilitate its integration into the clinical workflow.

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Section: Discussionsupporting

confidence: 77%

First validation of a model-based hepatic percutaneous microwave ablation planning on a clinical dataset

Frackowiak,

Van den Bosch,

Tokoutsi

et al. 2023

Sci Rep

View full text Add to dashboard Cite

show abstract

“…This study includes perfusion cooling effect prescribed in liver tissue and on segmented vessels in a similar way as in our biophysical model. Performance metrics at the aggregated data level (Figure 3) compares very well with reported values from validation studies in literature 11,13,15 using RFA or cryoablation: Dice coefficient close to 0.7 and Hausdorff distance ranging between 2.3 and 3 mm.…”

Section: Discussionsupporting

confidence: 75%

“…Model-based thermal ablation planning is a promising approach to assist the radiologist with the procedure, providing essential information on treatment settings. This has been shown in several studies for cryoablation, radiofrequency (RF), microwave (MW) and laser ablation in (pre-)clinical scenarios [11][12][13][14][15][16][17][18] . In this study, a biophysical model of thermal ablation is integrated in a prototype software which processes magnetic resonance imaging (MRI), or computed tomography (CT) imaging acquired during the regular clinical workflow.…”

Section: Introductionmentioning

confidence: 78%

Model-based hepatic percutaneous microwaveablation planning. First validation on a clinical dataset

Frackowiak

Bosch

Tokoutsi

et al. 2023

Preprint

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A model-based planning tool, integrated in an imaging system, is envisioned for CT-guided percutaneous microwave ablation. This study aims to evaluate the biophysical model performance, by comparing its prediction retrospectively with the actualablation ground truth from a clinical data set in liver. The biophysical model uses a simplified formulation of heat depositionon the applicator and a heat sink related to vasculature to solve the bioheat equation. A performance metric is defined toassess how the planned ablation overlaps the actual ground truth. Results demonstrate superiority of this model predictioncompared to manufacturer tabulated data and a significant influence of the vasculature cooling effect. Nevertheless, vasculatureshortage due to branches occlusion and applicator misalignment due to registration error between scans affects the thermalprediction. With a more accurate vasculature segmentation, occlusion risk can be estimated, whereas branches can be usedas liver landmarks to improve the registration accuracy. Overall, this study emphasizes the benefit of a model-based thermalablation solution in better planning the ablation procedures. Contrast and registration protocols must be adapted to facilitate itsintegration into the clinical workflow.

show abstract

“…The high cost associated with PNCL animal laboratory models is mostly related to the development of new techniques [ 30 , 31 ]. While digital courses have been organized for educating individuals in bronchoscopy and chest tube insertion procedures, no such courses have been developed for PNCL training [ 32 ]. Virtual reality has been used in surgical skill training with robotic simulators [ 33 ].…”

Section: Discussionmentioning

confidence: 99%

Simulation education utilizing phantom and angle reference guide in pulmonary nodule CT localization

Tsai,

Hsieh

et al. 2023

Heliyon

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Evaluation of a numerical simulation for cryoablation – comparison with bench data, clinical kidney and lung cases

Cited by 10 publications

References 32 publications

First validation of a model-based hepatic percutaneous microwave ablation planning on a clinical dataset

First validation of a model-based hepatic percutaneous microwave ablation planning on a clinical dataset

Model-based hepatic percutaneous microwaveablation planning. First validation on a clinical dataset

Simulation education utilizing phantom and angle reference guide in pulmonary nodule CT localization

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