“…Tertiary prevention for chronic disease management was supported primarily by care access expansion [20,58,103,178,181,189], app-driven [35,64,140,149,176,249], and patient-centered [38,97,241,245] approaches. Overall, DHIs decreased disease severity and associated comorbidities; lowered the numbers of emergency department visits, hospitalizations, and 30-day readmissions; increased the receipt of follow-up care; improved medication adherence in the identified studies [20,35,58,64,97,103,149,176,199,245,249]; and improved the quality or effectiveness of health services by technology implementation [24,38,103,140,171,178,186,189,249]. Disease areas targeted by DHIs included diabetes [38,97,171,176], hypertension [97,140,149], asthma [103,181,…”