Evaluation of a Powered Intraosseous Device for Bone Marrow Sampling.

Cohen, Stephen C.; Soroka, J.M.

doi:10.1182/blood.v110.11.5150.5150

Cited by 7 publications

(11 citation statements)

References 1 publication

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In this study we investigated the facility of obtaining BM core biopsies from small dogs using a 15ga needle from the EZ‐IO Intraosseous Infusion System. We chose this system because (1) a biopsy obtained using a 15ga needle would likely be the smallest core BM biopsy that might yield a diagnostic specimen; (2) the trochar tip of the stylet might facilitate penetration of the cortex better than the bevel tip of a Jamshidi needle; (3) a power driver might facilitate needle advancement; and (4) use of a similar system (OnControl) resulted in improved success of BM aspiration in people . The EZ‐IO system was chosen over the OnControl system because only the former was available; its needles are designed for intraosseous fluid administration and not BM core biopsy and, therefore, have no capture mechanism, such as the tapered end of a Jamshidi needle or split stylet of a Conrad‐Crosby needle.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Comparison of canine core bone marrow biopsies from multiple sites using different techniques and needles

Abrams‐Ogg

Defarges

Foster

et al. 2012

Veterinary Clinical Pathol

View full text Add to dashboard Cite

Background Commonly used 11 or 13ga needles are relatively large for collection of bone marrow (BM) biopsies from small dogs. Objectives The aims of this study were to assess ease of BM collection and quality of specimens obtained from small dogs using 13 and 15ga needles and to determine if specimen encasement would improve quality. Methods Humeral and iliac biopsies obtained from 17 Beagle dogs with a 15ga needle and a power driver were compared with humeral biopsies obtained with a 13ga Jamshidi needle. Ease of collection (scored as 1 [very difficult] to 5 [very easy] for 3 components of collection with scores summed), section quality (scored as 1 [poor] to 5 [good]), and lesions at collection sites were scored. Quality of additional humeral biopsies obtained with a 15ga needle and wrapped in tissue paper prior to fixation was assessed. Results Use of a 15ga needle to obtain a humeral BM biopsy was significantly easier (mean score ± SD = 13.6 ± 1.7) than obtaining humeral BM using a 13ga needle (11.4 ± 1.6; P < .001) or obtaining iliac BM using a 15ga needle (10.9 ± 2.0, P < .001). Quality of humeral biopsies obtained with a 13ga needle (3.9 ± 1.2) was better than for biopsies of the humerus (1.9 ± 1.3, P < .001) or ilium (1.4 ± 0.6, P < .001) using a 15ga needle. Only sites sampled with a 13ga needle were identifiable grossly after the procedure. In most biopsies, cell density and cellularity were lower when a 15ga needle was used. Paper‐wrapping of biopsies did not improve quality. Conclusions In small dogs, collection of humeral BM biopsies using a 15g needle is feasible and more easily accomplished than collection using a 13ga needle. Hematopoiesis may be underestimated in specimens collected using the smaller needle.

show abstract

Section: Discussionmentioning

confidence: 99%

“…The system also includes 15ga × 25–90 mm needles for BM aspiration. This system has been reported to be easy and rapid compared with conventional techniques and to result in less pain for patients . Other power drivers are available for rapid placement of needles for intraosseous fluid therapy.…”

Section: Introductionmentioning

confidence: 99%

Comparison of canine core bone marrow biopsies from multiple sites using different techniques and needles

Abrams‐Ogg

Defarges

Foster

et al. 2012

Veterinary Clinical Pathol

View full text Add to dashboard Cite

show abstract

“…It is also an essential component of the staging process for patients newly diagnosed with lymphoproliferative diseases and certain non-hematopoietic malignancies. Bone marrow examination is instrumental in determining the extent of marrow damage among patients exposed to radiation, drugs, chemicals, and other myelotoxic agents [ 3 ].…”

Section: Introductionmentioning

confidence: 99%

“…The device utilizes a battery-powered drill to insert the bone marrow needle into the iliac bone of adult patients with minimal operator exertion. An evaluation of the first generation device by Cohen and Gore indicated that the device was safe, as well as faster and easier to use than the traditional manual procedure [ 3 ]. The current generation of the device was also assessed in a non-controlled evaluation with similar results [ 7 ].…”

Section: Introductionmentioning

confidence: 99%

Using a Powered Bone Marrow Biopsy System Results in Shorter Procedures, Causes Less Residual Pain to Adult Patients, and Yields Larger Specimens

Berenson

Yellin

Blumenstein³

et al. 2011

Diagn Pathol

View full text Add to dashboard Cite

BackgroundIn recent years, a battery-powered bone marrow biopsy system was developed and cleared by the U.S. Food and Drug Administration to allow health care providers to access the bone marrow space quickly and efficiently. A multicenter randomized clinical trial was designed for adult patients to determine if the powered device had advantages over traditional manually-inserted needles in regard to length of procedure, patient pain, complications, user satisfaction, and pathological analysis of the specimens.MethodsAdult patients requiring marrow sampling procedures were randomized for a Manual or Powered device. Visual Analog Scale (VAS) pain scores were captured immediately following the procedure and 1 and 7 days later. Procedure time was measured and core specimens were submitted to pathology for grading.ResultsTen sites enrolled 102 patients into the study (Powered, n = 52; Manual, n = 50). Mean VAS scores for overall procedural pain were not significantly different between the arms (3.8 ± 2.8 for Powered, 3.5 ± 2.3 for Manual [p = 0.623]). A day later, more patients who underwent the Powered procedure were pain-free (67%) than those patients in the Manual group (33%; p = 0.003). One week later, there was no difference (83% for Powered patients; 76% for Manual patients.) Mean procedure time was 102.1 ± 86.4 seconds for the Powered group and 203.1 ± 149.5 seconds for the Manual group (p < 0.001). Pathology assessment was similar in specimen quality, but there was a significant difference in the specimen volume between the devices (Powered: 36.8 ± 21.2 mm3; Manual: 20.4 ± 9.0 mm3; p = 0.039). Two non-serious complications were experienced during Powered procedures (4%); but none during Manual procedures (p = 0.495).ConclusionsThe results of this first trial provide evidence that the Powered device delivers larger-volume bone marrow specimens for pathology evaluation. In addition, bone marrow specimens were secured more rapidly and subjects experienced less intermediate term pain when the Powered device was employed. Further study is needed to determine if clinicians more experienced with the Powered device will be able to use it in a manner that significantly reduces needle insertion pain; and to compare a larger sample of pathology specimens obtained using the Powered device to those obtained using traditional manual biopsy needles.

show abstract

“…These findings were not consistent with past research with regard to significantly larger sample sizes. [ 6 8 13 14 ] In addition, some past studies found the manual technique to produce on an average more evaluable marrow specimens;[ 14 ] however, this study found the two techniques to be very comparable. Comparable samples are in line with one other researcher's findings, which also identified crush artifact in the motorized device specimens.…”

Section: Discussionmentioning

confidence: 70%

Comparison of Bone Marrow Biopsy Specimens Obtained Using a Motorized Device and Manual Biopsy Systems

Glennon

Woodroof

Kambhampati

et al. 2018

Asia-Pacific Journal of Oncology Nursing

View full text Add to dashboard Cite

Objective:Bone marrow biopsy is an essential component in the diagnosis of hematopoietic disorders. Researchers evaluated the quality of bone marrow biopsy tissue acquired with a motorized bone marrow biopsy device versus a standard manual device based on the following criteria: biopsy length, percentage of aspiration artifact/intrastromal hemorrhage, length of nonhematopoietic bone, and overall quality of the sample.Methods:Bone marrow biopsies (motorized, n = 30; manual, n = 120) from two academic medical centers were evaluated by two board-certified hematopathologists. For each specimen, the following parameters were recorded: biopsy length (cm), aspiration artifact (assessed in intervals of ≤10%, 11%–25%, 26%–50%, 51%–75%, and >75%), length (cm) of nonhematopoietic biopsy (e.g., cortical bone and skin), and overall quality of sample (inadequate, suboptimal, adequate, and excellent).Results:Operators from two centers included physicians and nurse practitioners. The manual system was superior to the powered drill with respect to the amount of crush artifact (0.15 cm ± 0.01 vs. 0.24 cm ± 0.04, P = 0.01 [t-test]). There was a trend toward less aspiration artifact/intrastromal hemorrhage with the use of the manual biopsy; however, the difference was not statistically significant (P = 0.06). There was no statistically significant difference in the overall biopsy size, biopsy length, amount of nonhematopoietic elements, and overall adequacy of the sample.Conclusions:There was no significant difference in the biopsy length, amount of nonhematopoietic elements, and overall adequacy of the sample. Results suggest that the manual bone marrow biopsy device has significantly less crush artifact of the specimen and has a trend toward less aspiration artifact/intrastromal hemorrhage as well.

show abstract

Evaluation of a Powered Intraosseous Device for Bone Marrow Sampling.

Cited by 7 publications

References 1 publication

Comparison of canine core bone marrow biopsies from multiple sites using different techniques and needles

Comparison of canine core bone marrow biopsies from multiple sites using different techniques and needles

Using a Powered Bone Marrow Biopsy System Results in Shorter Procedures, Causes Less Residual Pain to Adult Patients, and Yields Larger Specimens

Comparison of Bone Marrow Biopsy Specimens Obtained Using a Motorized Device and Manual Biopsy Systems

Contact Info

Product

Resources

About