The aim of this study was to evaluate the effectiveness of the REPRISE care bundle (CB) model for pressure ulcer (PU) prevention in intensive care patients and to determine the impact of the training provided to nurses on their knowledge base and attitudes. This study has an experimental design. The study was conducted in the anaesthesia and resuscitation intensive care unit on a total of 72 patients. The prevalence of PU was compared between the control group and the REPRISE‐CB group. For the nurses, 50 nurses working in the ICU were included in the study. The nurses' knowledge and attitudes towards PU were compared before and after the training. The data were analysed using a statistical program. The incidence of IW was significantly lower in the intervention group (13.9%) compared to the control group (38.9%) (p < 0.05). The study showed that oedema, low albumin levels, low mean blood pressure and low Braden Scale scores were significant risk factors for the development of PU. In addition, the training provided to nurses was found to significantly improve their knowledge and attitudes (p < 0.05). It was concluded that REPRISE‐CB was effective in the prevention of PU and that nurses' knowledge increased with training.