Evaluation of a Rotating Disc Type Reservoir-Oxygenator.

Rm, Berne; Fs, Cross; Hirose, Yuya; Rd, Jones; Eb, Kay

doi:10.3181/00379727-93-22710

Cited by 53 publications

(10 citation statements)

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“…Ten dogs were put on complete cardiopulmonary bypass using an occlusive, precalibrated Sigmamotor pump and a rotating disc oxygenator. 5 The heart was isolated from the preparation and total systemic flow was maintained constant at 100 cc./Kg./min. of body weight with the aid of an electromagnetic flowmeter.…”

Section: Methods and Resultsmentioning

confidence: 99%

Effects Of Low Molecular Weight Dextran On Peripheral Blood Flow With Controlled Cardiac Output

Kilman¹,

Waldhausen²,

Schumacker³

1967

Annals of Surgery

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IT HAS BEEN shown by other investigators that low molecular weight dextran increases cardiac output and limb blood flow. The present experiment was designed to compare the effect of intravenously administered low molecular weight dextran on hind limb blood flow and vascular resistance and on total peripheral resistance in a control series of dogs and in a group in which the cardiac output was kept constant. Methods and ResultsTwenty mongrel dogs weighing from 12.2 to 17.0 Kg. were anesthetized with 30 mg./Kg. sodium pentobarbital intravenously. Three mg./Kg. of body weight of Heparin were given intravenously. In 10 dogs, direct measurement of limb blood flow was determined by a method which involved cannulating the femoral vein, allowing the blood to drain into a calibrated burette, and returning the blood to a jugu-

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Section: Methods and Resultsmentioning

confidence: 99%

Effects Of Low Molecular Weight Dextran On Peripheral Blood Flow With Controlled Cardiac Output

Kilman¹,

Waldhausen²,

Schumacker³

1967

Annals of Surgery

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“…By the mid-1960s, two other direct-contact oxygenators had been standardized for clinical usage. The 1956 Kay-Cross disc oxygenator, developed by Kay and Cross et al [25,26] was based off of Bjork's [17] 1948 design. By using partially-immersed rotating disks, onto filmed venous blood, the design sought to increase oxygenation rates over stationaryscreen methods.…”

Section: Direct-contact Oxygenators For Clinical Usagementioning

confidence: 99%

Bioengineering Progress in Lung Assist Devices

2021

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Artificial lung technology is advancing at a startling rate raising hopes that it would better serve the needs of those requiring respiratory support. Whether to assist the healing of an injured lung, support patients to lung transplantation, or to entirely replace native lung function, safe and effective artificial lungs are sought. After 200 years of bioengineering progress, artificial lungs are closer than ever before to meet this demand which has risen exponentially due to the COVID-19 crisis. In this review, the critical advances in the historical development of artificial lungs are detailed. The current state of affairs regarding extracorporeal membrane oxygenation, intravascular lung assists, pump-less extracorporeal lung assists, total artificial lungs, and microfluidic oxygenators are outlined.

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“…16 Bjørk, in Stockholm, used vertical rotating discs dipping into a compartmentalized blood pool to perfuse brain; 17 the essential difference between this and the more commonly used Cleveland Kay/Cross oxygenator being the presence of these baffles in Bjørk's blood pool. 18 John Gibbon, at the Thomas Jefferson University in Philadelphia in 1939, in whole animal perfusion, made use of a vertical rotating cylinder on the inside of which blood was sprayed, 18 with turbulence to turn over the blood surface exposed to oxygen produced by a fly-screen mesh lining. 19 Later, he turned to a bank of stationary vertical stainless steel mesh screens, the crucial part of the circuitry being the recirculating pump, which maintained constant the blood flow down them.…”

Section: Types Of Oxygenatormentioning

confidence: 99%

Perfusion in Britain: the early days

Braimbridge

2004

Perfusion

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Experimental perfusion was largely the province of Germany in the nineteenth century but in the mid-twentieth century the focus of perfusion switched to the USA with the explosive clinical advances of Lillehei, Kirklin and Cooley. British clinical perfusion started with Melrose in 1953 at the Postgraduate Medical School in London but, as in other centres at that time, stopped due to the high mortality. The arrival of hands-on experience of American expertise via returning research fellows and other visitors to the USA enabled the first successful on-going series to begin at the Hammersmith Hospital with Cleland in 1957 and then to spread around the country. The various problems of those early 1950s days are described in the units starting then.

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Evaluation of a Rotating Disc Type Reservoir-Oxygenator.

Cited by 53 publications

References 0 publications

Effects Of Low Molecular Weight Dextran On Peripheral Blood Flow With Controlled Cardiac Output

Effects Of Low Molecular Weight Dextran On Peripheral Blood Flow With Controlled Cardiac Output

Bioengineering Progress in Lung Assist Devices

Perfusion in Britain: the early days

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