Evaluation of acellular dermal matrix allograft [Alloderm<sup>®</sup>] with coronally positioned flap in the treatment of Miller's Class I or Class II gingival recession

Kanth, K Lakshmi; Swarna, Chakrapani; Swamy, D Narasimha; Kumar, Santosh

doi:10.4103/jdrntruhs.jdrntruhs_74_17

J NTR Univ Health Sci

2018

DOI: 10.4103/jdrntruhs.jdrntruhs_74_17

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Evaluation of acellular dermal matrix allograft [Alloderm^®] with coronally positioned flap in the treatment of Miller's Class I or Class II gingival recession

K Lakshmi Kanth

Chakrapani Swarna

D Narasimha Swamy

et al.

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Micro‐needling versus acellular dermal matrix in RT1 gingival recession coverage: A randomized clinical trial

Zaaya,

Elbattawy,

Yusri

et al. 2024

J of Periodontal Research

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AimsThis randomized trial assessed for the first time the efficacy of coronally advanced flap (CAF) followed by micro‐needling (MN) in contrast to CAF with acellular dermal matrix (ADM) on gingival thickness (GT, primary outcome), keratinized tissue width (KTW), clinical attachment level (CAL), probing depth (PD), recession depth (RD), recession width (RW), recession reduction (Rec‐Red), complete root coverage (CRC) and percentage of root coverage (all secondary outcomes) in management of RT1 gingival recession in patients with thin gingival phenotype.MethodsA total of 24 patients (n = 24) with a thin gingival phenotype and single RT1 gingival recession in the aesthetic zone were randomly allocated to test‐ (CAF + MN; n = 12) or control group (CAF + ADM; n = 12). All clinical parameters were evaluated at baseline, 3 and 6 months.ResultsBoth groups independently demonstrated significant gain in GT, RW, RD, CAL, PD, Rec‐Red, CRC and percentage of root coverage, with reduced PI and BOP (p < .05) at 3 and 6 months, without intergroup differences (p > .05). At 6 months, KTW gain was significantly higher in CAF + MN (5.08 ± 0.9 mm) than in CAF + ADM‐group (4.25 ± 1.06 mm; p < .05). Stepwise linear regression model with GT as dependent variable showed that base‐line GT was the only statistically significant predictor for GT with a direct correlation between base‐line GT and GT after 6 months.ConclusionCAF followed by MN could represent a promising graft‐less approach for increasing gingival thickness, comparable to CAF with ADM, with superior keratinized tissue width improvement, in the treatment of RT1 recession defects in patients with thin gingival phenotype.

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Micro‐needling versus acellular dermal matrix in RT1 gingival recession coverage: A randomized clinical trial

Zaaya,

Elbattawy,

Yusri

et al. 2024

J of Periodontal Research

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Efficacy of Acellular Dermal Matrix in Soft Tissue Augmentation Around Dental Implants: A Systematic Review and Meta-Analysis

Yaghini

Mogharehabed

Feizi

et al. 2022

Journal of Oral Implantology

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This study was done to perform a systematic review and meta-analysis of the studies on the efficacy of acellular dermal matrix in increasing the Soft Tissue Thickness (STT) and Keratinized Mucosal Width (KMW) around dental implants. The PubMed, Scopus, Cochrane, Web of Science, and ProQuest databases were searched by July 2020 to retrieve relevant studies. Depending upon the heterogeneity of included studies, the Weighted Mean Difference (WMD) with 95% confidence interval was calculated using either fixed or random-effects model. Based on the meta-analysis of 6 studies, the effect of acellular dermal matrix on STT and KMW was significant (WMD: 1.07 (95%CI: 0.34, 1.79) P=0.004, and WMD: 1.99 (95%CI: 0.88, 3.09), P<0.001, respectively). Further, a comparison between the efficacy of the acellular dermal matrix and the control group, which included the autogenous soft tissue augmentation techniques, showed no statistically significant differences between groups (STT: WMD: 0.24 (95%CI: -0.26, 0.74) P=0.161 and KMW: WMD: -0.23 (95%CI: -0.68, 0.22), P=0.324). The subgroup analysis showed that simultaneous augmentation and implant placement were increased by 0.23 mm in the KMW, and the placement of acellular dermal matrix around loaded implants caused 0.5 mm decrease in the KMW, which was not statistically significant. Accordingly, it is possible to substitute acellular dermal matrix for soft tissue augmentation around dental implants..

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Evaluation of acellular dermal matrix allograft [Alloderm^®] with coronally positioned flap in the treatment of Miller's Class I or Class II gingival recession

Cited by 2 publications

References 5 publications

Micro‐needling versus acellular dermal matrix in RT1 gingival recession coverage: A randomized clinical trial

Micro‐needling versus acellular dermal matrix in RT1 gingival recession coverage: A randomized clinical trial

Efficacy of Acellular Dermal Matrix in Soft Tissue Augmentation Around Dental Implants: A Systematic Review and Meta-Analysis

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Evaluation of acellular dermal matrix allograft [Alloderm®] with coronally positioned flap in the treatment of Miller's Class I or Class II gingival recession

Cited by 2 publications

References 5 publications

Micro‐needling versus acellular dermal matrix in RT1 gingival recession coverage: A randomized clinical trial

Micro‐needling versus acellular dermal matrix in RT1 gingival recession coverage: A randomized clinical trial

Efficacy of Acellular Dermal Matrix in Soft Tissue Augmentation Around Dental Implants: A Systematic Review and Meta-Analysis

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Product

Resources

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Evaluation of acellular dermal matrix allograft [Alloderm^®] with coronally positioned flap in the treatment of Miller's Class I or Class II gingival recession