Evaluation of Acetaminophen and Aspirin in the Relief of Preoperative Dental Pain

Korberly, Barbara H.; Schreiber, Glenn F.; Kilkuts, Arthur; Orkand, Richard K.; Segal, Herman

doi:10.14219/jada.archive.1980.0038

Cited by 6 publications

(3 citation statements)

References 9 publications

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“…Our finding that age had no effect on the analgesic function of Panadol ®and Panadol-Extra® support the various reports in the literature that paracetamol equally relieved mild to moderate pain in children as well as in adults [7][8][9][10] . Panadol® was found to have produced significant differences in tooth sensitivity at baseline compared with measurements taken at 30, 60, 90 and 120 minutes.…”

Section: Resultssupporting

confidence: 87%

Comparative study of the therapeutic effects of brands of paracetamol (acetaminophen) on experimentally induced dental pain

Fagade

2004

Afr. J. Oral. Health

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SummaryObjectives: To compare the therapeutic effects of two brands of Paracetamol: Panadol® (paracetamol 1000mg) and Panadol-Extra®( paracetamol 1000mg and 60mg caffeine) on the perception of dental pain. Method: The setting for the study was the Oral Diagnosis Unit of the Dental Hospital, Obafemi Awolowo University Teaching Hospitals' Complex, Ile-Ife, Osun State, Nigeria. The Experimental design was a single blind quasiexperimental repeated measure. Twenty volunteers with healthy permanent upper right central incisors were the subjects of the study. Using the Digitest Pulp Vitality Tester as a stimulator, the pain thresholds of the right maxillary central incisors were detected. Subjects were then given 1000mg of paracetamol (Panadol®) or 1000mg of paracetamol and 60 mg caffeine (Panadol -Extra®) orally and the pain thresholds were again detected and recorded at 30. 60, 90 and 120 minutes after drug ingestion. At one-week interval, subjects' baseline pain thresholds were recorded and they were given the other brand of the drug. Pain thresholds were recorded at 30,60, 90 and 120 minutes intervals. The data were analysed using the SPSS for windows (Release 9.0 version), p-value ≤ 0.05 was considered significant. Results: Age and gender did not have any significant effect on the baseline or mean scores for both drugs. Overall, Panadol® and Panadol -Extra® individually demonstrated significant differences in tooth sensitivity when compared with the baseline. A comparison of the effects of both drugs however showed no significant difference in their effects on dental pain perception. Conclusion: Although both drugs had significant therapeutic effects on baseline dental pain perception, a comparison of their effects showed no significant difference in their effects on the pain.

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Section: Resultssupporting

confidence: 87%

Comparative study of the therapeutic effects of brands of paracetamol (acetaminophen) on experimentally induced dental pain

Fagade

2004

Afr. J. Oral. Health

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“…Acetaminophen decreases acute dental pain[4–5] and is frequently used by patients who have toothaches. [6] While acetaminophen is safe when used as directed, unintentional overdose of acetaminophen has serious consequences including hepatic injury and hepatic failure.…”

Section: Introductionmentioning

confidence: 99%

Dental pain as a risk factor for accidental acetaminophen overdose: a case-control study

Vogel

Heard

Carlson

et al. 2011

The American Journal of Emergency Medicine

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“…Korberly studied patients presenting to a dental clinic for acute pain and found that both acetaminophen (1 g) and aspirin (1 g) decreased pain relative to placebo. [ 5 ] These studies all suggest that non-prescription analgesics are an effective therapy for dental pain.…”

Section: Introductionmentioning

confidence: 99%

Overuse of non-prescription analgesics by dental clinic patients

et al. 2008

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Evaluation of Acetaminophen and Aspirin in the Relief of Preoperative Dental Pain

Cited by 6 publications

References 9 publications

Comparative study of the therapeutic effects of brands of paracetamol (acetaminophen) on experimentally induced dental pain

Comparative study of the therapeutic effects of brands of paracetamol (acetaminophen) on experimentally induced dental pain

Dental pain as a risk factor for accidental acetaminophen overdose: a case-control study

Overuse of non-prescription analgesics by dental clinic patients

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