Evaluation of Administration of Activated Charcoal in the Home

Spiller, Henry A.; Rodgers, George C.

doi:10.1542/peds.108.6.e100

Cited by 26 publications

(14 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Home administration of activated charcoal to children by caregivers is interesting conceptually but has been met with contradictory results in practice. 11,12 In one study, none of 15 subjects were able to complete a therapeutic dose. In another, a case series based at the Kentucky Regional Poison Center found that home administration of charcoal could be achieved within 1 hour of ingestion in 95% of cases but in only 33% of those waiting for treatment in an emergency department.…”

Section: Timing Of Charcoal Administrationmentioning

confidence: 99%

Activated Charcoal Administration in a Pediatric Emergency Department

Osterhoudt¹,

Alpern²,

Durbin³

et al. 2004

Pediatric Emergency Care

View full text Add to dashboard Cite

Despite published guidelines, children treated in an emergency department rarely received charcoal within 1 hour of ingestion. Gastric tube administration of charcoal varies by age and is partly subjective in its application. We found no evidence that excipient flavoring of charcoal improved success of administration. Pulmonary aspiration of charcoal, although uncommon, should be considered when assessing the risk of therapy. We offer a report of symptomatic constipation from single-dose charcoal.

show abstract

Section: Timing Of Charcoal Administrationmentioning

confidence: 99%

Activated Charcoal Administration in a Pediatric Emergency Department

Osterhoudt¹,

Alpern²,

Durbin³

et al. 2004

Pediatric Emergency Care

View full text Add to dashboard Cite

show abstract

“…No evidence was found to suggest that activated charcoal is efficacious as a component of first aid for acute poisoning, although 2 small LOE 5 studies 14,15 suggest that it may be safe to administer. One LOE 3 study 16 demonstrated that the majority of children will not take the recommended dose of activated charcoal.…”

Section: Consensus On Sciencementioning

confidence: 99%

Part 13: First Aid

Markenson¹,

Ferguson²,

Chameides³

et al. 2010

Circulation

View full text Add to dashboard Cite

The International First Aid Science Advisory Board identified 38 questions in first aid practice that had not been subjected to an evidence review process or that needed to be updated since the 2005 process. Two or more members of the International First Aid Science Advisory Board volunteered to independently review the scientific literature and complete an evidence-based review worksheet summarizing the literature (see Part 2 of this supplement for additional information). After the evidence was presented to the full board, a draft consensus summary of the scientific evidence and a draft consensus treatment recommendation were developed and represented at a subsequent meeting. Thus, each question, evidence-based review, draft summary of science, and draft treatment recommendation was presented and discussed on 2 separate occasions, and a Consensus on Science and Treatment Recommendation was reached by the Board. This document is a report of the group's consensus.As in 2005, the worksheets revealed the continuing paucity of scientific evidence to support specific first aid interventions. Very little research is being conducted in first aid, and most of the recommendations are extrapolations from research and experience in other medical venues, animal studies, and case series. It is hoped that this document will be a stimulus to future research in first aid. First Aid for Medical Emergencies SummaryThe medical questions addressed include poisoning, anaphylaxis, oxygen administration, and aspirin administration for a suspected coronary event.No changes were recommended for first aid management of acute poisoning.In reviewing epinephrine administration for anaphylaxis, evidence was found that laypeople and some medical and prehospital professionals are unable to recognize the signs and symptoms of anaphylaxis and therefore cannot, without training, make an independent decision to administer epinephrine with an auto-injector or to administer a second dose if the first is not effective. This issue takes on added importance in view of legislation in some jurisdictions that permits these actions.No evidence was found, except in decompression injuries, to support the routine administration of oxygen by first aid providers.The administration of aspirin to a victim experiencing chest discomfort is problematic. The literature is clear on the benefit of early administration of aspirin in an acute coronary event, except when there is a clear contraindication, such as aspirin allergy or a bleeding disorder. Less clear, however, is whether first aid providers can recognize the signs and symptoms of an acute Consensus on ScienceThere are no human studies on the effect of treating oral caustic exposure with dilution therapy. One in vitro LOE 5 chemistry study 2 demonstrated no benefit from the addition of large volumes of diluent to either a strong base or a strong acid. Five LOE 5 animal studies 3-7 demonstrated histological benefit to the esophagus when a diluent was administered following exposure to an alkali or acid. Treat...

show abstract

“…Two studies found a high acceptance rate (83-90%) in children offered AC [69, 70]. In contrast, Kornberg reported that only 21/70 (30%) of children in the ED with an ingestion voluntarily took oral charcoal; the rest received it by nasogastric tube [71].…”

Section: What Are the Risks Of Giving Activated Charcoal?mentioning

confidence: 99%

Activated Charcoal for Acute Poisoning: One Toxicologist’s Journey

Olson

2010

J. Med. Toxicol.

View full text Add to dashboard Cite

Evaluation of Administration of Activated Charcoal in the Home

Cited by 26 publications

References 27 publications

Activated Charcoal Administration in a Pediatric Emergency Department

Activated Charcoal Administration in a Pediatric Emergency Department

Part 13: First Aid

Activated Charcoal for Acute Poisoning: One Toxicologist’s Journey

Contact Info

Product

Resources

About