Evaluation of amnion in creation of neovagina in women with Mayer-Rokitansky-Kuster-Hauser syndrome

Vatsa, Richa; Bharti, Juhi; Roy, Kallol Kumar; Kumar, Sunesh; Sharma, Jai Bhagwan; Singh, Neeta; Singhal, Seema; Meena, Jyoti

doi:10.1016/j.fertnstert.2017.05.026

Cited by 32 publications

(22 citation statements)

References 27 publications

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“…Akle et al (1981) found no evidence of infections since the amnion has an antibacterial effect. Vatsa et al (2017) performed an analysis in 50 patients with vaginal agenesis that were submitted to neovaginoplasty with amnion. All patients obtained successful results with vaginal length and sexually active life.…”

Section: Discussionmentioning

confidence: 99%

Study and evaluation of neovagina epithelium

Piazza¹

2021

JBRA Assisted Reproduction

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Section: Discussionmentioning

confidence: 99%

Study and evaluation of neovagina epithelium

Piazza¹

2021

JBRA Assisted Reproduction

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“…Small intestine mucosa, absorbable adhesion barrier, buccal mucosa, amnion membrane, peritoneum, tilapia fish skin, in vitro cultured vaginal tissue are the published materials that were used to create a vagina. [4][5][6][7][8][9][10][11] This technique has a short recovery period because of not involving any abdominal process. However, using graft materials increases the cost of the operation.…”

Section: Discussionmentioning

confidence: 99%

“…The first approach is the Mc Indoe method 3 , a vaginal surgery consisting of insertion a created vagina (with numerous materials like an autologous skin graft, invitro cultured vaginal tissue, acellular collagen, amniotic membrane, fish skin, buccal mucosa) into the dissected pouch between rectum and bladder. [4][5][6][7][8][9][10][11] The second approach is the Vechietti operation which requires long-term abdomen-vaginal traction with special instruments. [12][13][14] This method is including both vaginal and abdominal (laparotomy or laparoscopy) surgery.…”

Section: Introductionmentioning

confidence: 99%

Sexual Outcomes and Motherhood Plans of The Mayer Rokitansky Küster Hauser Syndrome Patients Operated with Uncu Modified Remnant-Supported Laparoscopic Double-Layer Peritoneal Pull-Down Vaginoplasty Technique

Aslan¹,

Gurbuz

Orhan

et al. 2021

Preprint

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Objective: To determine the sexual outcomes and motherhood plans of the Mayer Rokitansky Küster Hauser (MRKH) Syndrome patients operated with Uncu Modified Remnant-Supported Laparoscopic Double-Layer Peritoneal Pull-Down Vaginoplasty operation Design: Cohort Study Setting: Tertiary University Hospital Patients: Women with MRKH syndrome Methods: This study involves the patients with MRKH syndrome who underwent Uncu Modified Remnant-Supported Laparoscopic Double-Layer Peritoneal Pull-Down Vaginoplasty Operation between the years 2008-2020. The first step of the study is about our surgical technique outcomes. The second step consists of long-term results for sexual functioning which was assessed by female sexual function index (FSFI) survey and motherhood plans by another survey. Main Outcome Measure: FSFI and Motherhood Survey Results Results Total 42 patients with MRKH syndrome underwent vaginoplasty operation. At least one year after surgery all patients was physically examined. The mean vaginal length was 8.4 + 1.9 cm. The mean FSFI score was 31.5 + 3.9 (min:24-max:36) Thirty-six of the patients answered a survey about motherhood. Thirty-one of the patients (86%) had a desire for motherhood. Most of the patients (21/31 – 68%) choose uterine transplantation as a first option. Three of the patients (9.6%) choose mater option and seven patients (22.5%) wants to be a mother by adoption. Conclusion: Uncu Modified Remnant-Supported Laparoscopic Double-Layer Peritoneal Pull-Down Vaginoplasty Operation is a satisfactory option for patients with MRKH syndrome with high FSFI scores and low complication rates. But creating only a neovagina is not enough for these patients, because of nearly 70% motherhood desire by uterine transplantation.

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“…Puede además cursar concomitantemente con otras alteraciones tales como anormalidades renales en el 40% de las pacientes y anormalidades esqueléticas en el 10-15% de los casos 8 .…”

Section: Introductionunclassified

“…Múltiples procedimientos quirúrgicos y no quirúrgicos han sido descritos, los cuales tienen como objetivo la creación de una neovagina de tamaño y condiciones fisiológicas adecuadas que permitan una función cotial normal, sin embargo, el método y el injerto ideal aun son debatidos 5,8,10,11 .…”

Section: Introductionunclassified

Reporte de serie de casos: neovagina en pacientes con Síndrome Mayer-Rokitansky-Kuster-Hauser

Echavarría-Restrepo

Echavarría-Medina

Londoño³

et al. 2019

Rev. chil. obstet. ginecol.

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RESUMENINTRODUCCIÓN: La ausencia congénita de vagina es una condición poco común, algunas causas son el síndrome de Mayer-Rokitansky-Kuster-Hauser y la insensibilidad periférica a los andrógenos. Múltiples técnicas quirúrgicas y no quirúrgicas se han descrito para el manejo de esta condición, siendo el objetivo principal la creación de un canal vaginal de diámetro y longitud adecuada que permitan restaurar la función coital. El objetivo de este estudio es detallar la experiencia del procedimiento de neovagina con la técnica quirúrgica de McIndoe en pacientes con Mayer-Rokitansky-Kuster-Hauser realizados en la Unidad de Uroginecología de la Clínica Universitaria Bolivariana. METODOLOGÍA: Reporte de 5 casos de pacientes con agenesia de vagina secundarios al síndrome de Mayer-Rokitansky-Kuster-Hauser, a las cuales se les realizó neovagina con la técnica de McIndoe con algunas modificaciones en el molde para el implante de piel. RESULTADOS: Se incluyeron cinco pacientes con diagnóstico de Mayer-Rokitansky-Kuster-Hauser, todas tenían desarrollo de características sexuales secundarias, perfil hormonal normal, y un cariotipo XX. Se utilizó la técnica quirúrgica de McIndoe para la realización de la neovagina sin complicaciones intraoperatorias asociadas y con adecuada evolución posoperatoria, con una longitud vaginal entre 7-9 cm y 3 pacientes con vida sexual activa. El tiempo de estancia hospitalaria fue 7 a 9 días. CONCLUSIÓN: La técnica quirúrgica de McIndoe es una opción para restaurar la función sexual en mujeres con agenesia vaginal con resultados favorables. El tiempo para decidir su realización es electivo, sin embargo, se debe contar con madurez física y emocional para ser llevado a cabo. Las pacientes de nuestro reporte tenían una edad promedio de 18 años.Palabras clave: Neovagina, vaginoplastia, Agenesia vaginal, síndrome de Mayer-Rokitansky-Kuster-Hauser

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Evaluation of amnion in creation of neovagina in women with Mayer-Rokitansky-Kuster-Hauser syndrome

Cited by 32 publications

References 27 publications

Study and evaluation of neovagina epithelium

Study and evaluation of neovagina epithelium

Sexual Outcomes and Motherhood Plans of The Mayer Rokitansky Küster Hauser Syndrome Patients Operated with Uncu Modified Remnant-Supported Laparoscopic Double-Layer Peritoneal Pull-Down Vaginoplasty Technique

Reporte de serie de casos: neovagina en pacientes con Síndrome Mayer-Rokitansky-Kuster-Hauser

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