Evaluation of Anterior Maxillary Horizontal Ridge Augmentation With Simultanous Implant Placement Using Cerabone® Versus Cerabone® Combined With Platelet Rich Plasma (Randomized Clinical Trial)

Abstract

INTRODUCTION:Rehabilitation of the anterior maxilla using dental implants is frequently problematic because of the deficiency of alveolar ridge width. Under certain conditions ridge augmentation with simultaneous implant placement is recommended. OBJECTIVES: To evaluate horizontal augmentation of narrow anterior maxillary alveolar ridge with simultaneous implant placement using Cerabone® with and without platelet rich plasma (PRP). MATERIALS AND METHODS: In this study, 14 implants were placed in patients with insufficient alveolar ridge width in the maxillary lateral incisor region. Patients were divided into two groups; In Group "1" Cerabone® only was used as an augmentation material while in Group "2" a mixture of Cerabone® and PRP was used. A collagen membrane was used to cover the grafting material. Postoperative pain was assessed using visual analogue scale. Healing and postoperative edema were evaluated. Cone Beam Computed Tomography (CBCT) was obtained before surgery, immediately postoperatively and after 6 months so that the labial bone width and bone density were evaluated. Osstell was used to evaluate implant stability quotient (ISQ) during surgery and after 6 months. RESULTS: All implants in both groups were successfully osseointegrated and functionally stable. No significant difference in postoperative pain, edema or wound healing was detected between the two groups. The mean percentage of change in ISQ was superior in Group "2" when compared to Group "1", but statistically there was no significant difference (P=0.898). The labial bone width in Group "2" was significantly higher than that of Group "1" (P=0.002). The mean percentage of change in labial bone density was 57.95% in Group "1" and 112.52% in Group "2" (P=0.848). CONCLUSION: Cerabone® can be used effectively for guided bone regeneration around dental implant in narrow maxillary anterior alveolar ridges. Moreover, the addition of PRP has a positive effect on bone regeneration around implants.

Evaluation of Mineralized Plasmatic Matrix Versus Platelet Rich Plasma in Deficient Anterior Maxillary Alveolar Ridge: A Randomized Controlled Clinical Trial

“…They found that the alveolar ridge width increase from one week to four months postoperatively was statistically significant. Furthermore, Ibrahim et al 18 in their study found that PRP when mixed with xenograft had a statistically significant impact on buccal bone thickness at the sixth months postoperatively. Additionally, Eskan et al 20 conducted a randomized clinical trial in which they compared horizontal ridge augmentation using PRP mixed with allograft versus allograft alone; in both groups the graft was covered by a membrane.…”

“…In addition, Ibrahim et al 18 reported no statistically significant difference in implant stability measured by Osstell between implants placed simultaneously with horizontal ridge augmentation using xenograft mixed with PRP and those placed simultaneously with xenograft without PRP. However, they stated that there was a statistically significant difference in implant stability between immediate postoperative and six months postoperatively.…”

Esthetic Rehabilitation of Partially Edentulous Ridge With Horizontal Bone Augmentation Using the Sausage Technique: A Report of Two Cases

“…The implant success rate was 100% during the follow-up period [ 8 ]. Ibrahim et al [ 9 ] evaluated the augmentation of the narrow anterior maxillary alveolar ridge in a randomized clinical trial. There was new bone formation six to seven months postoperatively following xenograft placement.…”

The Effectiveness of the Addition of Platelet-Rich Fibrin to Bovine Xenografts in Sinus and Bone Ridge Augmentation: A Systematic Review

“…The particle size of this material is 0.25 to 2 mm [9,10]. BioOss TM has been shown to be effective in sinus floor augmentation [11], socket or alveolar ridge preservation, horizontal and vertical augmentation [12,13], and peri-implant defects [14,15].…”