Evaluation of anti-depressant and anxiolytic activity of Rasayana Ghana Tablet (A compound Ayurvedic formulation) in albino mice

Deole, Yogesh S; Chavan, Sulakshan S; Ashok, B K; Ravishankar, B; Thakar, Anup B; Chandola, HM

doi:10.4103/0974-8520.93918

Cited by 31 publications

(19 citation statements)

References 20 publications

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“…This is further explained by Isela E. Juarez-Rojopa et al, 2014 that steroids hamper the glucose absorption by inhibiting the hydrolyzing enzymes and that helped in hypoglycaemic activity 53 . Saponins of bitter melon also showed hypoglycemic activity in alloxan-induced hyperglycemic mice which increased the mass of β cells in the pancreas and insulin production studied by scientists 54 .…”

Section: Resultsmentioning

confidence: 96%

Untitled

2017

IJPSR

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ABSTRACT:Tribulus terristris is a well known medicinal plant as antiinflammatory, antimicrobial and nephroprotective etc. It is a very good drug for urinogenital problems, hepatic problems, oxidative stress etc. The aim of the study is to compare the depression induced by PCPA and STZ treated diabetic depression in mice and which could be restored by the ethanolic exact of fruits of Tribulus terristris in 21 days.

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Section: Resultsmentioning

confidence: 96%

Untitled

2017

IJPSR

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“…This plant is demonstrated to have diuretic activity [161], aphrodisiac activity [162], antiurolithic activity [163], immunomodulatory activity [164], antidiabetic activity [165], hypolipidemic [166], central nervous system (CNS) activity [167], anticancer activity [168], and larvicidal activity [169].…”

Section: Scientific Evidencesmentioning

confidence: 99%

Medicinal Plants of West Godavari

Pola¹,

Kadali²

2018

Drug Discovery - Concepts to Market

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Medicinal plants are one of the nature's greatest gifts to the mankind. Each plant will have an exquisite deal of character, which can act as an antidote to various of diseases. Traditional medicine has become a vital alternative source of medicine all over the world today with some approximation of about 80% of the primary health care system in some developing countries. Medicinal plants are known to comprise of hundreds of active constituents that may be potentially useful for the development of therapeutic agents. The development of therapeutic agents involves the isolation and identification of bioactive compounds from plant materials which is crucial for drug discovery. Researchers from all around the globe have focused on drug discovery from the natures' wonder medicinal plants, forming an important group of complementary and alternative medicine (CAM) therapy. West Godavari is a part of Andhra Pradesh, India, which hosts several plants that have high therapeutic significance. Each of the plants has a unique feature which can be employed for healing of various lethal diseases. The present examination intends to review the therapeutic plant assets of West Godavari area Andhra Pradesh. This evaluation also offers the critical elements which include medicinal properties of various medicinal plants found in West Godavari district of Andhra Pradesh, India. Drug Discovery -Concepts to Market 102 Drug Discovery -Concepts to Market 104 Drug Discovery -Concepts to Market 106 Drug Discovery -Concepts to Market 110 2.18.1. Scientific evidences This plant is verified to have anticarcinogenic and anti-lipid peroxidative [181], anti-inflammatory and analgesic [182], in vitro antioxidant [183], anticancer activity [184], and in vitro anthelmintic activity [185]. Tectona grandisT. grandis Linn. belongs to family Verbenaceae is one of the most well-known timbers in the world and is famous for its dimensional stability, extreme durability, and hardness which also resists decay even when unprotected by paints and preservatives. This plant is commonly called as teak. It is one of the most famous heartwood of the world. Timber value of teak has been well-known for decades [186,187]. Scientific evidencesThis plant is verified to have hair growth activity [188], cytotoxic activity [189], anti-hemolytic anemia activity [190], hypoglycemic activity [191], anti-inflammatory activity [192], diuretic activity [193], and gastroprotective activity [194]. Tamarindus indica L.Tamarindus indica or tamarind regarded as a tropical fruit tree native to the African savannahs and it is found in numerous tropical nations. It is arranged as a monospecific class in the group of Leguminosae. The sweet and harsh taste of its natural product mash is utilized to add flavor to neighborhood cooking styles. Other than culinary, tamarind is likewise utilized as a part of the conventional drug as purgative, diuretic, antibacterial operators and also in the treatment of fever and malarial contaminations [195,196]. Scientific evidencesThis plant is verified ...

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“…Modern medical science is always curious for better treatment approaches with minimum side-effects and simultaneously maximum efficacy. Ayurveda also bears the responsibility to provide an effective psycho-active drug to combat with various diseases [4] . Based on the importance of herbs and essential minerals on stress-related disorders authors newly designed a proprietary herbomineral based formulation consisting of nine ingredients viz.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Stress Biomarkers after Oral Administration of the Consciousness Energy Healing Treated Novel Herbomineral Formulation in Male Sprague Dawley Rats

Trivedi¹,

Branton²,

Trivedi³

et al. 2019

IJNBD

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The study aim was to investigate the anti-stress effect of Consciousness Energy Healing Treated test formulation using behavioral tests, hormonal levels and antioxidants in male Sprague Dawley rats. The test formulation was divided into two parts, one was represented as control, while the other was treated with Biofield Energy by Mr. Mahendra Kumar Trivedi (The Trivedi Effect® - Consciousness Energy Healing) and defined as the Biofield Energy Treated sample. OFT data showed the frequency of total square-cross was significantly (p ≤ 0.05) increased by 49.11% in the animals per se received Biofield Energy Treatment (-15 days) (G6) compared to stress control (G2). Freezing time was significantly (p ≤ 0.01) reduced by 21.48%, 43.79%, 42.79%, 44.79%, and 58.21% in the Biofield Energy Treated test formulation (G5), G6, Biofield Energy Treated test formulation (-15 days) (G7), Biofield Energy Treated animals with Biofield Energy Treated test formulation (-15 days) (G8) and Biofield Energy Treatment per se to animals plus untreated test formulation (G9), respectively compared to G2. Defecation was significantly (p ≤ 0.05) decreased by 92.01% in the G8 compared to G2. Urination was significantly reduced by 53.19% and 46.81% in the G8 and G9, respectively compared to G2. FST showed the number of climbing was significantly (p ≤ 0.05) increased by 37.5%, 70.83%, 50%, 102.17%, and 68.83% in the G5, G6, G7, G8, and G9, respectively compared to G2. Swimming time was significantly (p ≤ 0.05) increased by 30.09%, 70%, 17.66%, 83%, and 100% in the G5, G6, G7, G8, and G9, respectively compared to G2. The resting time was significantly (p ≤ 0.05) decreased by 21.54%, 50%, 55%, and 63% in the G5, G6, G8, and G9, respectively compared to G2. Corticosterone was significantly decreased by 29%, 26%, 31%, and 36% in the G5, G6, G8, and G9, respectively compared to G2. Testosterone was significantly increased by 275% (p ≤ 0.05), 83%, 70%, 181%, and 164% in the G5, G6, G7, G8, and G9, respectively compared to G2. SOD was significantly (p ≤ 0.001) increased by 15%, 53%, 57%, 61%, and 58% in the G5, G6, G7, G8, and G9, respectively compared to G2. Further, CAT was significantly increased by 19% and 14% in the G5 and G6, respectively compared to G2. Overall, data suggest that Biofield Energy Treatment per se and Biofield Energy Treated test formulation have significant anti-stress activity and could be utilized in various stress related disorders like asthma, obesity, diabetes, headaches, depression and anxiety, gastrointestinal problems, Alzheimer's disease, accelerated aging, and premature death.

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Evaluation of anti-depressant and anxiolytic activity of Rasayana Ghana Tablet (A compound Ayurvedic formulation) in albino mice

Cited by 31 publications

References 20 publications

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Medicinal Plants of West Godavari

Evaluation of Stress Biomarkers after Oral Administration of the Consciousness Energy Healing Treated Novel Herbomineral Formulation in Male Sprague Dawley Rats

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