Evaluation of Anti-Ulcer and Anti-Diarrhoeal Activities of the Ayurvedic Formulation Udumbara Ghanasatwa

Abstract

Muduli et al.: Anti-Ulcer and Anti-Diarrhoeal Activities of Udumbara GhanasatwaUdumbara Ghanasatwa is a classical Ayurvedic formulation prescribed for the treatment of gastritis, indigestion and diarrhoea without any scientific validation of its pharmacological action. The present study investigated the antiulcer activity of Udumbara Ghanasatwa at two graded doses by pylorus ligation model in rats. The anti-diarrhoeal activity was also evaluated in terms of the defecation amount/frequency as well as intestinal fluid enteropooling in castor oil induced diarrhoea. The Ghanasatwa exerted significant protective effects in both pylorus ligation-induced gastric ulcer and castor oil induced diarrhoeal models in a dose-dependent manner. Findings obtained in the study justified the clinical applications of Udumbara Ghanasatwa in the treatment of gastric ulcers and diarrhoea. These pharmacological effects exerted by Ghanasatwa may be attributed to the antioxidant phytoconstituents like flavonoids and tannins present in it.

Investigating the Antimicrobial Effect of Loranthus europeaus Leaf Hydroalcoholic Extract Against Methicillin-Resistant Staphylococcus aureus

“…Medicinal plants have useful properties, such as antibacterial, antiparasitic, antifungal, antiulcer,antiinflammatoryand antioxidant properties (Baidya et a., 2020;Das et al, 2018;Muduli et al, 2022;Bose et al, 2019). The essential oils of medicinal plants with antimicrobial effects on a wide range of organisms, as well as their ability to be used as food in some cases, and their side effects being less than common antibiotics, can eventually replace antibiotics (Anand et al, 2019).…”