Evaluation of antibacterial activity of "Mangabarana" Austroplenckia populnea Reissek (Celastraceae)

Abstract

RESUMO: "Avaliação da atividade antibacteriana de "Mangabarana" Austroplenckia populnea Reissek (Celastraceae)". Austroplenckia populnea (Mangabarana) é popularmente utilizada em Minas Gerais, Brasil, para o tratamento de disenterias. A ela também são atribuídas propriedades antitumoral e antiúlcera. Extratos de partes desta planta obtidos com solventes de diferentes polaridades e triterpenos pentacíclicos (TTPCs) isolados destes, por métodos fitoquímicos foram submetidos a testes de atividade antibacteriana. Os resultados mostraram a existência desta atividade e abriram perspectivas para a continuidade dos estudos com outros compostos orgânicos isolados desta planta.Unitermos: Austroplenckia populnea, Celastraceae, atividade antibacteriana, triterpenos pentacíclicos.ABSTRACT: Austroplenckia populnea (Mangabarana) is popularly used by people from Minas Gerais, Brazil for dysenteries diseases treatment. Antitumor and antiulcer activities were also attributed to this plant. Extracts obtained using solvents of different polarities and pentacyclic triterpenes (PCTTs) isolated from these extracts through phytochemical methods were submitted to antibacterial assays. The results showed the existence of this activity and open perspectives for news studies with other organic compounds isolated from this plant.

Effect of constituents from samaras of Austroplenckia populnea (Celastraceae) on human cancer cells

“…(1984) [ 19 ] and Matos (1997) [ 20 ] were identified in the extracts isolated from samaras of A. populnea the presence of long chain hydrocarbons (the most part in SAPEH), triterpenes, flavonoids and catechins. This result is in agreement with previous works in which were isolated mainly pentacyclic triterpenes [ 9 , 12 ].…”

“…During continued phytochemical investigation of extracts from leaves, stems and roots of A. populnea an extensive number of constituents have been isolated, finding the main compounds as different series of pentacyclic triterpenes, such as friedelanes, agarofurans and others [ 8 , 9 ]. When subjected to in vitro assays, some constituents of A. populnea presented properties such as antibacterial [ 9 , 12 ], antitrypanosomal [ 13 ], anti-inflammatory, antinociceptive [ 14 ], antiulcerogenic, analgesic [ 15 ] and male contraceptive effect [ 16 , 17 ]. In accordance to Monache et al .…”

Ecological phytochemistry of Cerrado (Brazilian savanna) plants

“…A total of 12 triterpenes were isolated from Austroplenckia populnea extracts and, of these, pristimerin (33) showed significant activity against Escherichia coli and abruslactone A (34) against S. aureus (Miranda et al, 2009b). A mixture of the phenylpropanoid glycosides verbascoside (35) and isoverbascodide (36) was isolated from Arrabidaea harleyi (Lima et al, 2003) (Fig.…”

“…The African grasses produce large quantities of biomass that dehydrate during the dry seasons and act as a 'fuel' to very fierce fires, that are more frequent, stronger and longer than Cerrado plants can resist (Klink and Machado 2005;Carmo et al 2011). Fierce fires increase the mortality of plants, especially young individuals and seeds, and result in more open physiognomies, with different patterns of water use and carbon flux efficiencies (Medeiros and Miranda 2005;Miranda et al 2009a).…”

Celastraceae Family: Source of Pentacyclic Triterpenes with Potential Biological Activity

“…2 Somente o cerrado, abriga mais de 10.000 espécies de plantas, 3 sendo que muitas são utilizadas na medicina popular pelas comunidades nativas. Neste cenário, espécies da família Celastraceae merecem destaque, como por exemplo, Austroplenckia populnea utilizada para tratamento de disenterias, 4 Salacia elliptica para tratamento da febre, ferimentos e diabetes, 5 Maytenus rigida para tratamento de infecções e inflamações, 6 entre outras.…”