Evaluation of Antibacterial Activity of a Bioactive Restorative Material Versus a Glass-Ionomer Cement on Streptococcus Mutans: In-Vitro Study

Abstract

Background: Dental caries management consists of both preventive and restorative approaches. Pediatric dentists can rely on many techniques and materials to restore decayed teeth, but a high failure rate is still observed, mainly due to secondary caries. New restorative bioactive materials combine the mechanical and aesthetic characteristics of resinous materials with the capability to remineralize and the antimicrobial properties of glass ionomers, thus counteracting the occurrence of secondary caries. The aim of this study was to assess the antimicrobial activity against Streptococcus mutans of a bioactive restorative material (ACTIVA™ BioActive-Restorative™-Pulpdent©) and a glass ionomer cement with silver particles added (Ketac™ Silver—3M©), using agar diffusion assay. Methods: Each material was formed into disks of 4 mm in diameter, and four discs of each material were placed on nine agar plates. The analysis was repeated seven times. Results: Both materials showed statistically significant growth inhibition properties against S. mutans (p < 0.05). The difference in the effectiveness of the two materials was not statistically significant. Conclusion: Both ACTIVA™ and Ketac™ Silver can be recommended since both are similarly effective against S. mutans. However ACTIVA™, given its bioactivity and better aesthetics and mechanical properties compared to GICs, may provide better clinical performance.

Antimicrobial effect of biosynthesis of selenium nanoparticles by Pseudomonas aeruginosa on bacteria isolated from wounds and burns

“…and Kolmogorov-Smirnov test of distribution of variables. Usually, the numerical variables distributed between the treated groups were compared using a two-way ANOVA test (univariate and multivariate analysis so that the variance was obtained for the least significant difference (LSD) , and all data were expressed as a standard deviation (mean ± SD) and the significance of the differences was discovered when... p < 0.05 This experiment was conducted according to [13] .…”

Ozone Treatment for the Management of Caries in Primary Dentition: A Systematic Review of Clinical Studies

“…In recent years, non-invasive or minimally-invasive approaches have spread widely in many medical and dental fields, especially in pediatric dentistry, with the implementation of more biologic atraumatic techniques [ 10 , 11 ] Modern minimally invasive approaches include selective or stepwise carious removal, also using atraumatic manual techniques along with chemo-mechanical procedures, non-restorative treatments, such as fluoride varnish or silver diamine fluoride applications, and new suitable restorative solutions and materials with bioactive properties [ 12 , 13 , 14 , 15 , 16 , 17 ]. Overall, these approaches allow more conservative and less time-consuming procedures, requiring less need for anesthetics and causing reduced post-operative discomfort [ 6 , 18 , 19 ].…”