Evaluation of antibacterial, teratogenicity and antibiofilm effect of sulfated chitosans extracted from marine waste against microorganism

Gomathy, Velu; Venkatesan, Manigandan; Narasimman, Vignesh; Aavula, Thabitha; Saravanan, R

doi:10.1177/08839115211014225

Cited by 11 publications

(2 citation statements)

References 31 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The higher toxicity level resulted in deformities such as yolk sac diffusion, delayed hatching, poor development, and death rate. The lowest concentrations, 0.125 μ g/ml and 0.25 μ g/ml, showed low pigmentation, tail bending, and body curvature, similarly to the control under constant observation in (Figures 5(a) and 5(b) ), and when compared to FA2, the teratogenic activity of the sulphated chitosan, FA1, showed less toxicity in zebrafish larvae [ 27 ].…”

Section: Resultsmentioning

confidence: 87%

Antioxidant and Teratogenic Activities of Formulated Agar Extracted from Brown Seaweed Turbinaria conoides against Zebrafish Larvae

Aavula

Narasimman

Ramachandran

et al. 2022

Evidence-Based Complementary and Alternative Medicine

Self Cite

View full text Add to dashboard Cite

This study examines the antioxidant and teratogenic effects of two different type’s methods of formulating agar from Turbinaria conoides (T. conoides) using a zebrafish model. The agar was extracted using the aqueous extraction method and developed in two different formulations using separate procedures. Formulated agar1 (FA1) used a higher concentration of the ingredients while formulated agar 2 (FA2) had a lesser concentration. The two unique formulated agars (FAs) were studied using biochemical composition, Fourier infrared (FT-IR) spectroscopy, gas chromatography-mass spectroscopy (GC-MS), and scanning electron microscopy (SEM). The antioxidant activities of both FAs in vitro were shown to be significantly different ( P < 0.05 ) at various concentrations (60–180 μl/ml) in the study. The toxicity of the FAs was dose-dependent, with FA1 having the least teratogenic activity when compared to FA2. In comparison to FA2, FA1 was found to have higher antioxidant activity. At various concentrations (0.5, 0.25, and 0.125 μg/ml), the teratogenic activity of two FAs was examined in zebrafish embryos (ZFE) at 24, 48, 72, and 96 hours post fertilization (hpf). Both FAs exhibit dose-dependent toxicity and increased antioxidant activity, and this can be utilized as an alternative for standard antioxidants, according to this study.

show abstract

Section: Resultsmentioning

confidence: 87%

Antioxidant and Teratogenic Activities of Formulated Agar Extracted from Brown Seaweed Turbinaria conoides against Zebrafish Larvae

Aavula

Narasimman

Ramachandran

et al. 2022

Evidence-Based Complementary and Alternative Medicine

Self Cite

View full text Add to dashboard Cite

show abstract

“…Therefore, this process is considered an important step. Different types of chemicals were used and applied to test the efficacy of deproteinization 12 .…”

Section: Chemical Extractionmentioning

confidence: 99%

Extraction of Chitin and Chitosan from Marine Waste and its Applications on Food and Agriculture Products

Rajagopal,

Murugan,

Aavula

et al. 2022

Asian J. Biol. Sci

View full text Add to dashboard Cite

Chitin and chitosan are linear polysaccharides, structurally similar to cellulose, and have a set of unique characteristics such as biocompatibility, biodegradability to harmless products, non-toxicity, physiological inertness, antibacterial properties, heavy metal ion chelation, gel-forming properties, and, hydrophilicity and remarkable affinity to proteins. The motive of this review was to provide a literature review about chitin and chitosan. And also gives scientific research information about the context. This review reveals the chemistry of chitin and chitosan, various marine sources, different extraction methods and the different applications of chitin and chitosan in the food and agriculture industry.

show abstract

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

Harvey

2024

Mass Spectrometry Reviews

View full text Add to dashboard Cite

The use of matrix‐assisted laser desorption/ionization (MALDI) mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this review is the 12th update of the original article published in 1999 and brings coverage of the literature to the end of 2022. As with previous review, this review also includes a few papers that describe methods appropriate to analysis by MALDI, such as sample preparation, even though the ionization method is not MALDI. The review follows the same format as previous reviews. It is divided into three sections: (1) general aspects such as theory of the MALDI process, matrices, derivatization, MALDI imaging, fragmentation, quantification and the use of computer software for structural identification. (2) Applications to various structural types such as oligo‐ and polysaccharides, glycoproteins, glycolipids, glycosides and biopharmaceuticals, and (3) other general areas such as medicine, industrial processes, natural products and glycan synthesis where MALDI is extensively used. Much of the material relating to applications is presented in tabular form. MALDI is still an ideal technique for carbohydrate analysis, particularly in its ability to produce single ions from each analyte and advancements in the technique and range of applications show little sign of diminishing.

show abstract

Evaluation of antibacterial, teratogenicity and antibiofilm effect of sulfated chitosans extracted from marine waste against microorganism

Cited by 11 publications

References 31 publications

Antioxidant and Teratogenic Activities of Formulated Agar Extracted from Brown Seaweed Turbinaria conoides against Zebrafish Larvae

Antioxidant and Teratogenic Activities of Formulated Agar Extracted from Brown Seaweed Turbinaria conoides against Zebrafish Larvae

Extraction of Chitin and Chitosan from Marine Waste and its Applications on Food and Agriculture Products

Analysis of carbohydrates and glycoconjugates by matrix‐assisted laser desorption/ionization mass spectrometry: An update for 2021–2022

Contact Info

Product

Resources

About