Evaluation of antimicrobial property of modified acrylic resin–containing cetylpyridinium chloride

Verma, Tanvi; Sharma, Payal; Kumar, Piush; Tyagi, Kirti; Bhatnagar, Shalaj; Raza, Monis

doi:10.4103/jos.jos_6_19

Cited by 3 publications

(3 citation statements)

References 12 publications

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“…In acrylic resins modified with CPC, Tanvi Verma et al [ 38 ] observed that antibacterial activity was found in all CPC-containing acrylic resin specimens, but its effectiveness decreased with time. Al-Musallam et al [ 35 ] confirmed the maintenance of antimicrobial activity in CPC-modified orthodontic adhesive resin against Streptococcus mutans discs after being stored in distilled water for a 196-day testing period, with a small decline in the zones of bacterial inhibition as the aging time increased, which is in agreement with our findings.…”

Section: Discussionmentioning

confidence: 99%

“…CPC has been used as a powerful antimicrobial agent and has been frequently employed in various over-the-counter products, including buccal tablets [ 26 ], sanitizer [ 27 ], disinfecting liquids [ 28 ], cleaning agents for eatables [ 29 ], nasal sprays [ 30 ], mouthwashes [ 31 ], and toothpastes [ 32 ]. Even though there are not much data present in the literature regarding the incorporation of CPC into RBDCs, many other studies have confirmed its antimicrobial effect in different dental materials, for instance varnishes [ 33 ], adhesives [ 34 , 35 ], orthodontic primers [ 36 ], root canal sealers [ 37 ], acrylic resin [ 38 ], and cements [ 39 ]. In 2019, Kenya Matsuo et al [ 34 ] demonstrated, with the help of optical density and SEM, that CPC montmorillonite adhesives significantly inhibited the growth of Streptococcus mutans biofilms.…”

Section: Introductionmentioning

confidence: 99%

“…In 2019, Kenya Matsuo et al [ 34 ] demonstrated, with the help of optical density and SEM, that CPC montmorillonite adhesives significantly inhibited the growth of Streptococcus mutans biofilms. Tanvi Verma et al [ 38 ], in their study, analyzed the length of CPC release from modified acrylic and its antibacterial function. The authors observed that an increase in CPC concentration in the acrylic increased its antimicrobial activity.…”

Section: Introductionmentioning

confidence: 99%

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Exploring the Effect of Cetylpyridinium Chloride Addition on the Antibacterial Activity and Surface Hardness of Resin-Based Dental Composites

Khan,

Amin,

Amin

et al. 2024

Polymers

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The aim of this study was to evaluate the effect of cetylpyridinium chloride (CPC) addition on the antibacterial and surface hardness characteristics of two commercial resin-based dental composites (RBDCs). A total of two hundred and seventy (n = 270) specimens from Filtek Z250 Universal and Filtek Z350 XT flowable RBDCs were fabricated with the addition of CPC at 2 %wt and 4 %wt concentrations to assess their antibacterial activity using the agar diffusion test and direct contact inhibition test, and their surface hardness using the Vickers microhardness test after 1 day, 30 days, and 90 days of aging. A surface morphology analysis of the specimens was performed using a scanning electron microscope (SEM). The RBDCs that contained 2 %wt and 4 %wt CPC demonstrated significant antibacterial activity against Streptococcus mutans up to 90 days, with the highest activity observed for the 4 %wt concentration. Nevertheless, there was a reduction in antibacterial effectiveness over time. Moreover, compared to the control (0 %wt) and 2 %wt CPC groups, the universal RBDCs containing 4 %wt CPC exhibited a notable decrease in surface hardness, while all groups showed a decline in hardness over time. In conclusion, the satisfactory combination of the antibacterial effect and surface hardness property of RBDCs was revealed with the addition of a 2 %wt CPC concentration.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Exploring the Effect of Cetylpyridinium Chloride Addition on the Antibacterial Activity and Surface Hardness of Resin-Based Dental Composites

Khan,

Amin,

Amin

et al. 2024

Polymers

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Effect of attachment flash on clear aligner force delivery: an in vitro study

Kiong,

Ashari,

Zamani

et al. 2024

BMC Oral Health

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Background The introduction of auxiliaries such as composite attachment has improved the force delivery of clear aligner (CA) therapy. However, the placement of the attachment may give rise to a flash, defined as excess resin around the attachment which may affect CA force delivery. This in vitro study aims to determine the differences in the force generated by the attachment in the presence or absence of flash in CA. Materials and methods Tristar Trubalance aligner sheets were used to fabricate the CAs. Thirty-four resin models were 3D printed and 17 each, were bonded with ellipsoidal or rectangular attachments on maxillary right central incisors. Fuji Prescale pressure film was used to measure the force generated by the attachment of CA. The images of colour density produced on the films were processed using a calibrated pressure mapping system utilising image processing techniques and topographical force mapping to quantify the force. The force measurement process was repeated after the flash was removed from the attachment using tungsten-carbide bur on a slow-speed handpiece. Results The intraclass correlation coefficient showed excellent reliability (ICC = 0.96, 95% CI = 0.92–0.98). The average mean force exerted by ellipsoidal attachments with flash was 8.05 ± 0.16 N, while 8.11 ± 0.18 N was without flash. As for rectangular attachments, the average mean force with flash was 8.48 ± 0.27 N, while 8.53 ± 0.13 N was without flash. Paired t-test revealed no statistically significant difference in the mean force exerted by CA in the presence or absence of flash for both ellipsoidal (p = 0.07) and rectangular attachments (p = 0.41). Rectangular attachments generated statistically significantly (p < 0.001) higher mean force than ellipsoidal attachments for flash and without flash. Conclusion Although rectangular attachment generated a significantly higher force than ellipsoidal attachment, the force generated by both attachments in the presence or absence of flash is similar (p > 0.05).

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Effect of antimicrobial agents on the oral microflora in patients undergoing fixed orthodontic therapy–An ex vivo comparative analysis

Shahi¹,

Kumar²,

Shetty³

et al. 2021

Journal of Orthodontic Science

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Aim: To evaluate and compare the efficacy of Ozonated Olive Oil Gel, Chlorhexidine gel, and Amflor (Fluoridated) mouthwash on reducing the count of Streptococcus mutans and Lactobacillus in patients undergoing fixed orthodontic therapy evaluated at different time intervals.Methods: Sixty patients undergoing orthodontic treatment were randomly divided into three groups (n = 20) based on antimicrobial agents used (Group 1: Ozonated olive oil gel; Group 2: Chlorhexidine gel; Group 3: Fluoridated mouthwash). Elastomeric modules from brackets were collected at T 0 (Fresh samples) and T 1 (2 nd week) and T 2 (4 th week) for assessment of the microbial growth. These collected modules were cultured and evaluated for the presence of Streptococcus Mutans and Lactobacilli and numbers of colonies were counted at each interval. Data obtained was subjected to statistical analysis using SPSS software (Version 20.0). Level of significance was kept at 5%. Intra-group and inter-group comparison between pretreatment, 2 nd week and 4 th week was done for each group using Wilcoxon signed rank test and Mann-Whitney U test.Results: There was presence of Streptococcus Mutans and Lactobacilli during orthodontic treatment which progressively increased from T o to T 1 and then declined from T 1 to T 2. The colony counts were maximum for Fluoridated mouthwash and least for Chlorhexidine and the results were statistically significant (P < 0.05). Conclusion:All three antimicrobial agents used were effective against Streptococcus mutans and Lactobacillus. Chlorhexidine proved to be more efficacious whereas Fluoridated mouthwash proved to be least effective against both Streptococcus mutans and Lactobacillus bacteria.

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Evaluation of antimicrobial property of modified acrylic resin–containing cetylpyridinium chloride

Cited by 3 publications

References 12 publications

Exploring the Effect of Cetylpyridinium Chloride Addition on the Antibacterial Activity and Surface Hardness of Resin-Based Dental Composites

Exploring the Effect of Cetylpyridinium Chloride Addition on the Antibacterial Activity and Surface Hardness of Resin-Based Dental Composites

Effect of attachment flash on clear aligner force delivery: an in vitro study

Effect of antimicrobial agents on the oral microflora in patients undergoing fixed orthodontic therapy–An ex vivo comparative analysis

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