Evaluation of Antimycotic Activity of Extracts of Marine Algae Collected from Red Sea Coast, Jeddah, Saudi Arabia

Sheikh, Huda M.; El-Naggar, Amal H.; Al-Sobahi, Danyah

doi:10.4236/jbm.2018.64004

Cited by 7 publications

(4 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…(Komari et al, 2017). Additionally, the current findings were consistent with those of (Sheikh et. al., 2018), who discovered that Chlorophyta had the strongest antifungal impact against Candida albican, Aspergillus flavus, and Aspergillus niger, followed by Rhodophyta.Additionally, our findings were consistent with those of (Saleh and Al-Mariri, 2017), who discovered that marine seaweeds Jania rubens (Rhodophyta) and Ulva lactuca (Chlorophyta) prevent two fungus strains (Candidaalbicans and Aspergillus niger utilizing algal extracts.…”

Section: Discussionsupporting

confidence: 92%

Antifungal Activities of the Marine Green and Red Macro Algae Extracts Against Some Phytopathogenic Fungi

Azzam,

El-Howeity,

Galal

et al. 2023

International Journal of Environmental Studies and Researches

View full text Add to dashboard Cite

Plant pathogenic fungi, in particular are the source of several plant diseases,often regarded as one of the primary causes of decreased food supply around the world. The spread of such pathogenic fungi results in considerable crop losses degrades fruits and vegetables, reduces food availability, and costs billions of dollars annually. Although fungicides made of synthetic chemicals are commonly used for managing fungal diseases, they are harmful for the environment. Marine algae present an environmentally friendly option in the search for various kinds of compounds with industrial uses. They are one of the richest marine sources with a variety of bioactive compounds. Two green algae (Ulva flexusoa and Enteromorpha intestinalis) and one red algae (Griffithsia teges) are explored in the current work. The three seaweeds' methanolic extracts were evaluated in vitro for their biological activity against Penicillium expansum and Fusarium oxysporum mycelial growth. The antifungal activity of each of the extracts employed in this study was evident. The resulting inhibition zone in mycelial growth of Fusarium oxysporum as affected by Enteromorpha intestinalis methanolic extractwas 37 mm, whereas that for Penicillium expansum was 32.6 mm. Gallic acid in the Enteromorpha intestinalis extract was 0.22 mg/ml, Chlorogenic acid was 0.41 mg/ml, Daizein was 0.16 mg/ml, Querectin was 0.64 mg/ml, Cinnamic acid was 0.05 mg/ml, and Hesperetin was 0.14 mg/ml, according to the results of the phenolic analysis carried out by HPLC-LC1620A.Also Ulva flexusoacontain high amount of Querectin 0.26 mg/mland Griffithsia teges contain high amount of Gallic acid 0.81 mg/ml .These results suggest that the seaweeds employed in the study are a preferred and natural source of bioactive chemicals. Such natural products may have applications in the management of fungal diseases in organic farming and other sustainable agricultural practices.

show abstract

Section: Discussionsupporting

confidence: 92%

Antifungal Activities of the Marine Green and Red Macro Algae Extracts Against Some Phytopathogenic Fungi

Azzam,

El-Howeity,

Galal

et al. 2023

International Journal of Environmental Studies and Researches

View full text Add to dashboard Cite

show abstract

“…Antimicrobial activity of the Red Sea seaweeds against both bacteria and fungi has been established by several workers (Shanab, 2007;Salem et al, 2011;Selim, 2012 andSheikh et al, 2018). But there was variation in the antibacterial activities which may be due to the method and solvent used in the extraction and season at which samples were collected (Kandhasamy and Arunachalam, 2008).…”

Section: Antimicrobial Activity Of the Investigated Seaweedsmentioning

confidence: 99%

Evaluation of proximate composition, antioxidant and antimicrobial activities of some seaweeds from the Red Sea coast, Egypt.

El-Manawy¹,

Nassar²,

Fahmy³

et al. 2019

Egypt. J. of Aquatic Biolo. and Fish.

View full text Add to dashboard Cite

Nutritional composition, total Phenolic content, antioxidant and antimicrobial activities were assessed in the crude extracts of six seaweed species selected from the Red Sea coast, Hurghada, Egypt. These species are Caulerpa racemosa var. gracilis from Chlorophyta; Padina boergesenii, Polycladia myrica, Hormophysa cuneiformis and Sargassum aquifolium from Phaeophyta and Digenea simplex from Rhodophyta. The results of nutritional content revealed that, the tested seaweeds have high values of fibers (27.6-36.2% dry wt.), ash (24.7-35.8% dry wt.), and carbohydrates (23.4-35.7% dry wt.), medium values of moisture (2.4-10.8% dry wt.) and protein (4.8-7.1% dry wt.), while low values of total lipids (0.8-5.2% dry wt.) were detected. The highest total phenolic content (129.9 ± 1.8 mg GAE/g dry wt.) was detected in the brown seaweed, H. cuneiformis, and the lowest (31.3 ± 0.6 mg GAE/g dry wt.) was observed in the green seaweed C. racemosa. The antioxidant activity was detected using DPPH (2, 2-Diphenyl-2-picrylhydrazyl) radical scavenging activity and the highest activity was recorded in the brown seaweed H. cuneiformis, while the lowest activity was observed in the green seaweed C. racemosa. All the algal extracts were effective against Pseudomonas aeruginosa and Candida albicans, while the extract of H. cuneiformis is the only one that effective against Enterococcus faecalis and Staphylococcus aureus. None of the tested extracts was effective against Aspergillus niger. Overall, the results of this study indicated that the Red Sea seaweeds could be introduced as raw materials or some of their contents for nutrient supplementation in various food products.

show abstract

“…According to Aruna et al (2010) stated that among the marine algae tested, the brown alga, Sargassum wightii, exhibited the highest rate of antifungal activity, followed by the red alga, K. alvarezii. Oppositely, Sheikh et al (2018) reported that acetone was the most effective solvent for extracting bioactive chemicals from seaweeds with the highest antifungal activity. Our results showed that C. albicans and A. alternata were more resistant to the seaweed extracts (MIC= 15-70µg/mL).…”

Section: Discussionmentioning

confidence: 99%

Screening of Antifungal Activity of Bioactive Chemical Constituents in Some Brown Marine Macroalgae from the Red Sea, Egypt

et al. 2022

View full text Add to dashboard Cite

Marine habitats are a puddle of bioactive natural compounds that are not present in terrestrial natural products. Marine organisms such as macroalgae are sources of various natural antimicrobial compounds with biological and pharmacological activities (Ismail et al., 2016) as fungal infections are responsible for an extremely high degree of mortality in humans and aquaculture organisms (Rajkumar et al., 2018).A variety of solvents with different polarities S OME mycological strains have been reported to be resistant to commonly used drugs.As a result, the development of new and important antifungal drugs has become a global endeavor. This study investigated the antifungal activity of three brown marine macroalgae, Sargassum cinereum, Padina boergesenii, and Cystoseira myrica against three fungal dermatophytes, namely Candida albicans, Candida glabrata, and Candida tropicalis and two nondermatophytic, Fusarium oxysporum and Alternaria alternata using the disc diffusion assay. Algal extraction was performed using three organic solvents (acetone, ethanol, and methanol). The results showed that the seaweed extracts exhibited different patterns of antifungal activities. The ethanolic extract of Sargassum cinereum was the most active as compared to other organic extracts. The maximum antifungal activity of the S. cinereum ethanolic extract was 21.3 ± 0.32 and 18.8 ± 0.16mm against F. oxysporum and C. glabrata, respectively, followed by the methanolic extract of C. myrica (16.5 ± 0.21mm) against F. oxysporum, and ethanolic extract of P. boergesenii (16.3 ± 0.16mm) against C. glabrata. The minimal inhibitory concentrations (MICs) of the algal extracts for inhibiting the tested fungi were in a range of 8.5-70µg/mL. The ethanolic extract of S. cinereum had the lowest MIC value (8.5 ± 0.12µg/mL) against F. oxysporum. The gas chromatography-mass spectrometry of the ethanolic extracts revealed the presence of chemical constituents that could have significant antifungal effects in the brown marine macroalgae. The main constituents were the hexadecanoic acid methyl ester (palmitic acid); 3,7-dimethylocta-2,6-dienal; and octadecanoic acid methyl ester.

show abstract

Evaluation of Antimycotic Activity of Extracts of Marine Algae Collected from Red Sea Coast, Jeddah, Saudi Arabia

Cited by 7 publications

References 40 publications

Antifungal Activities of the Marine Green and Red Macro Algae Extracts Against Some Phytopathogenic Fungi

Antifungal Activities of the Marine Green and Red Macro Algae Extracts Against Some Phytopathogenic Fungi

Evaluation of proximate composition, antioxidant and antimicrobial activities of some seaweeds from the Red Sea coast, Egypt.

Screening of Antifungal Activity of Bioactive Chemical Constituents in Some Brown Marine Macroalgae from the Red Sea, Egypt

Contact Info

Product

Resources

About