Evaluation of antioxidant and mutagenic activities of honey-sweetened cashew apple nectar

Silva, Robson Alves da; Dihl, Rafael Rodrigues; Santos, Débora Nascimento e; Abreu, Bianca Regina Ribas de; Lima, Alessandro de; Andrade, Heloı́sa Helena Rodrigues de; Lehmann, Maurı́cio

doi:10.1016/j.fct.2013.08.026

Cited by 16 publications

(12 citation statements)

References 42 publications

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“…The positive control (urethane 20 mM) induced significant increases in the frequencies of all spot categories, when values for the HB cross were significantly higher when compared with the values observed for the ST cross. The frequencies of mutant clones from both the ST and HB crosses after exposure to the positive control were similar to previous results [26]. …”

Section: Resultssupporting

confidence: 90%

Surface Water Impacted by Rural Activities Induces Genetic Toxicity Related to Recombinagenic Events in Vivo

Neto

Carli

Kotzal

et al. 2016

IJERPH

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This investigation assessed the interaction of surface water samples with DNA to quantitatively and qualitatively characterize their mutagenic and/or recombinagenic activity. Samples were obtained at three different sites along the Tocantins River (Tocantins State, Brazil). The area has withstood the impact mainly of rural activities, which release different chemical compounds in the environment. The Drosophila melanogaster Somatic Mutation and Recombination Test (SMART) was performed in standard (ST) and high bioactivation (HB) crosses. SMART is useful for the detection of mutational and recombinational events induced by genotoxins of direct and indirect action. Results demonstrated that samples collected in both seasons were able to induce increments on the mutant spot frequencies in the larvae of the HB cross. Genotoxicity was related to a massive recombinagenic activity. The positive responses ascribed to only the HB cross means that it is linked to pro-genotoxins requiring metabolic activation. The SMART wing test in Drosophila melanogaster was shown to be highly sensitive to detect genotoxic agents present in the aquatic environment impacted by agriculture.

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Section: Resultssupporting

confidence: 90%

Surface Water Impacted by Rural Activities Induces Genetic Toxicity Related to Recombinagenic Events in Vivo

Neto

Carli

Kotzal

et al. 2016

IJERPH

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“…The amount of vitamin C (ascorbic acid) present in cashew juices was also measured [12,25], since cashew presents considerable amounts of this substance [26], which is associated with beneficial effects on human health and is considered a dietary supplement with antioxidant effects [27]. In this study, a mean value of 19.41 g / 100 ml was found, with no difference among groups.…”

Section: Discussionmentioning

confidence: 69%

Cariogenic and Erosive Potential of Industrialized Cashew Juice

Costa¹,

Carvalho²,

Peixoto³

et al. 2016

Pesqui. bras. odontopediatria clín. integr.

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Objective: To evaluate the cariogenic and erosive potential of industrialized cashew juice. Methods: Twenty-seven cashew juice samples of three different brands (n = 9) were analyzed for the following physicochemical parameters: pH, titratable acidity (TA), ascorbic acid, total soluble solids (TSS), TSS/TA ratio and reducing, non-reducing and total sugars. Assays were performed in triplicate and data were processed using ANOVA and Tukey test, considering α = 5%.

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“…Previous chemical analysis of this honey sample by our research group, showed a total phenolic content of 31.91 mg of gallic acid equivalents (GAE) per 100 g, and a weak antioxidant capacity, when evaluated using the DPPH model system (da Silva et al , 2013). Studies of the antimutagenic activity of honey are very scarce.…”

Section: Discussionmentioning

confidence: 82%

“…In that study, DPPH and/or β-carotene/linoleate systems demonstrated a weak antioxidant capacity of honey, HSCAN and cashew apple pulp. The absence of mutagenic activity for HSCAN was observed using both standard and high-bioactivation cross of the SMART (da Silva et al , 2013). …”

Section: Discussionmentioning

confidence: 99%

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DNA damage protective effect of honey-sweetened cashew apple nectar in Drosophila melanogaster

et al. 2016

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Fruits and derivatives, such as juices, are complex mixtures of chemicals, some of which may have mutagenic and/or carcinogenic potential, while others may have antimutagenic and/or anticancer activities. The modulating effects of honey-sweetened cashew apple nectar (HSCAN), on somatic mutation and recombination induced by ethyl methanesulfonate (EMS) and mitomycin C (MMC) were evaluated with the wing spot test in Drosophila melanogaster using co- and post-treatment protocols. Additionally, the antimutagenic activity of two HSCAN components, cashew apple pulp and honey, in MMC-induced DNA damage was also investigated. HSCAN reduced the mutagenic activity of both EMS and MMC in the co-treatment protocol, but had a co-mutagenic effect when post-administered. Similar results were also observed with honey on MMC mutagenic activity. Cashew apple pulp was effective in exerting protective or enhancing effects on the MMC mutagenicity, depending on the administration protocol and concentration used. Overall, these results indicate that HSCAN, cashew apple and honey seem capable of modulating not only the events that precede the induced DNA damages, but also the Drosophila DNA repair processes involved in the correction of EMS and MMC-induced damages.

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Evaluation of antioxidant and mutagenic activities of honey-sweetened cashew apple nectar

Cited by 16 publications

References 42 publications

Surface Water Impacted by Rural Activities Induces Genetic Toxicity Related to Recombinagenic Events in Vivo

Surface Water Impacted by Rural Activities Induces Genetic Toxicity Related to Recombinagenic Events in Vivo

Cariogenic and Erosive Potential of Industrialized Cashew Juice

DNA damage protective effect of honey-sweetened cashew apple nectar in Drosophila melanogaster

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