2011
DOI: 10.1111/j.1468-1293.2011.00915.x
|View full text |Cite
|
Sign up to set email alerts
|

Evaluation of antiretroviral-related errors and interventions by the clinical pharmacist in hospitalized HIV-infected patients

Abstract: ObjectivesThe aim of the study was to identify antiretroviral-related errors in the prescribing of medication to HIV-infected inpatients and to ascertain the degree of acceptance of the pharmacist's interventions. MethodsAn observational, prospective, 1-year study was conducted in a 750-bed tertiary-care teaching hospital by a pharmacist trained in HIV pharmacotherapy. Interactions with antiretrovirals were checked for contraindicated combinations. Inpatient antiretroviral prescriptions were compared with outp… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

2
61
0
2

Year Published

2012
2012
2018
2018

Publication Types

Select...
9

Relationship

0
9

Authors

Journals

citations
Cited by 50 publications
(65 citation statements)
references
References 10 publications
2
61
0
2
Order By: Relevance
“…145 Furthermore, when clinical pharmacists were actively involved in or leading the medication evaluation of HIV-positive patients being admitted to hospital, medication errors were prevented, error rates were further reduced, and the duration of uncorrected errors was significantly shorter. 8,149,157,158 Pharmacists can also be useful resources for residents and physicians, especially those with limited experience in HIV, who may be more prone to antiretroviral prescribing errors. 159,160 Pharmacists can provide advice regarding dosage adjustments to address drug interactions or organ insufficiencies, can suggest alternatives if current therapies or formulations are unsuitable or contraindicated, and can ensure that complete regimens are prescribed, including comedications, problems that a computerized physician order entry system is unlikely to be able to identify or help resolve.…”
Section: Medication Reconciliationmentioning
confidence: 99%
“…145 Furthermore, when clinical pharmacists were actively involved in or leading the medication evaluation of HIV-positive patients being admitted to hospital, medication errors were prevented, error rates were further reduced, and the duration of uncorrected errors was significantly shorter. 8,149,157,158 Pharmacists can also be useful resources for residents and physicians, especially those with limited experience in HIV, who may be more prone to antiretroviral prescribing errors. 159,160 Pharmacists can provide advice regarding dosage adjustments to address drug interactions or organ insufficiencies, can suggest alternatives if current therapies or formulations are unsuitable or contraindicated, and can ensure that complete regimens are prescribed, including comedications, problems that a computerized physician order entry system is unlikely to be able to identify or help resolve.…”
Section: Medication Reconciliationmentioning
confidence: 99%
“…substantially lower than in research done for HAART [29,[35][36][37]. It should be noted that the studies that were done for HAART comprised both adult and child participants.…”
Section: Resultsmentioning
confidence: 90%
“…18,25 These differences may be justified by factors such as ARV classes (NRTI, NNRTI and PI), adherence, toxicity, adverse reactions, incorrect drug combinations in coinfections, and pharmacogenetics of patients. 4,6,10,15,26 In our study, EFZ was the drug most often switched in the initial regimens. This is possibly due to the significant prevalence of CNS-related adverse events associated with this drug.…”
Section: Resultsmentioning
confidence: 99%
“…Due to the increasing number of PLWHA using HAART, treatment monitoring for the rational adherence of patients to therapy has become a priority, with improved clinical parameters and less risk of failure, hospitalization, costs, morbidity and mortality, longer survival and positive prevention with the adoption of healthy lifestyle habits. [8][9][10] In this context, we aimed to describe the profile of HIV+ patients seen at a reference center in Fortaleza/Ceará, who had their initial antiretroviral regimen modified in the first year of treatment, and the factors involved in the modifications of HAART during this period.…”
Section: Introductionmentioning
confidence: 99%