Evaluation of appropriate usage of fresh frozen plasma: Results of a regional audit in Iran

Epidemiology of blood component recipients in hospitals of Yazd, Iran

“…Other diagnosis categories with prominent plasma usage were neoplasm, neonatal and internal diseases. In the study of Mirzamani et al () in Gorgan, northern part of Iran, the largest proportion of plasma was used for patients with GI bleeding, neoplasm, patients who had undergone surgery or neonatal diseases.…”

“…The therapeutic dose of plasma is 10–20 mL kg −1 of body weight. Therefore, the plasma usage in most adult patients seems to be inadequate (Mirzamani et al , ).…”

Utilization of frozen plasma, cryoprecipitate, and recombinant factor VIIa for children with hemostatic impairments: An audit of transfusion appropriateness

“…Regular auditing of transfusion practice is an essential tool to assess practice patterns and evaluate appropriateness. Although numerous audits have evaluated transfusion practice in adults and pediatrics, most were performed retrospectively and therefore suffer limitations regarding bias and completeness of data capture . To better capture the circumstances of blood product ordering for pediatric patients, and thereby determine optimal educational interventions to improve practice, a prospective observational study was conducted with adjudication of each event.…”

Long-term audit of the use of fresh frozen plasma in a university hospital

“…Numerous publications have highlighted the need for and proven benefit of auditing the use of blood products as a reliable tool to uncover not only their inappropriate use but also to monitor the extent of the compliance with the set guidelines for the use of these products 5, 6, 7, 8, 10, 11, 12. The guidelines that are frequently followed are mostly from regulatory bodies such as the British Committee for Standards in Haematology (BCSH) Guidelines in the United Kingdom, 16 the American College of Pathologists (CAP) and the American Association of Blood Banks (AABB) in the USA 18 .…”

“…A survey of the literature uncovered numerous studies from developing countries on the trend of the use of FFP, showing a continuous reduction in its use. This reduction was generally attributed to the application of guidelines on the transfusion of blood products, the physicians that were educated on the proper use of FFP, and also the emphasis on the fact that no transfusion is completely free from the infectious and non-infectious risks of blood transfusion 1, 5, 6, 7, 8. Nonetheless, the inappropriate use of FFP is still widespread 8, 9, 10, 11, 12.…”