Evaluation of bioactive chemical composition, phenolic, and antioxidant profiling of different crude extracts of Sargassum coriifolium and Hypnea pannosa seaweeds

Sobuj, Mohammad Khairul Alam; Islam, Md. Ariful; Haque, Md. Amdadul; Islam, Md. Mohidul; Alam, Md. Jahangir; Rafiquzzaman, S. M.

doi:10.1007/s11694-020-00758-w

Cited by 38 publications

(19 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…TPC’s current observation is underpinned by the findings of other scholars 40 – 42 , who also reported that methanolic extract when compared to other extracts; extract has the most incredible volume of TPC. Similar results in red and brown seaweed obtained from the Bangladeshi coast 28 . Some academics reported 69.5 and 25.29 mg GAE/g, respectively in the methanolic extracts of P. tetrastromatica , which is a more petite figure than the one we have now 43 , 44 .…”

Section: Discussionsupporting

confidence: 81%

“…In the case of all antioxidant assays, it was observed that brown seaweed ( P. tetrastromatica ) showed higher activity compared with the red seaweed ( G. tenuistipitata ). An approach similar to ours has been presented earlier 28 , 48 . The antioxidant capacity of the crude extracts ordered in the rank methanol, ethanol and water extract (Fig.…”

Section: Discussionmentioning

confidence: 96%

“…In Bangladesh, however, there is a lack of information on available secondary metabolites and antioxidant properties of seaweed. However, other researchers explored Bangladeshi seaweeds, and a variety of phytochemicals and promising antioxidant properties were discovered 16 , 28 . Hence, in the present study, we used a combination of qualitative and quantitative tests (Phytochemical analysis and FTIR) to screen out for functionally bioactive compounds and determine antioxidant activities using various in vitro spectroscopic assays of different crude extracts of two significant Bangladeshi seaweeds ( P. tetrastromatica and G. tenuistipitata ).…”

Section: Discussionmentioning

confidence: 99%

“…The presence of any phytoconstituents primarily influenced by the dissolvable solvent used for extraction and the seaweed physicochemical properties. The essential bioactive compounds in seaweed can be screened using various methods while keeping different solvents and situations in consideration 28 . In this study, we used methanol, ethanol, and water extracts having a dielectric constant of about 33, 25, and 80, respectively 31 .…”

Section: Discussionmentioning

confidence: 99%

“…Previous researchers typically only investigated the proximate biochemical and nutritional analysis of the seaweed 26 , 27 . There is limited evidence in the literature regarding the bioactivity and antioxidant properties of seaweed obtained off the coast of Bangladesh 16 , 28 . This type of research is a primary step towards validating a seaweed species as an important commercial species.…”

Section: Introductionmentioning

confidence: 99%

See 4 more Smart Citations

Effect of solvents on bioactive compounds and antioxidant activity of Padina tetrastromatica and Gracilaria tenuistipitata seaweeds collected from Bangladesh

Sobuj

Islam

et al. 2021

Sci Rep

Self Cite

View full text Add to dashboard Cite

Seaweeds are now recognized as a treasure of bioactive compounds. However, the bioactivity of seaweed originating in Bangladesh is still unexplored. So, this study was designed to explore the secondary metabolites and antioxidant activities of solvent extracts of Padina tetrastromatica and Gracilaria tenuistipitata. Phytochemical screening and FTIR spectra confirm the diverse type of bioactive compounds. Antioxidant activity of extracts were evaluated by 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2, 2-Azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), reducing power (RP), phosphomolybdenum, hydrogen peroxide and nitric oxide (NO) scavenging assays. Here, methanolic extract of P. tetrastromatica showed highest amount of total phenolic content (85.61 mg of GA/g), total flavonoid content (41.77 mg of quercetin/g), DPPH (77.07%), ABTS (77.65%), RP (53.24 mg AAE/g), phosphomolybdenum (31.58 mg AAE/g), hydrogen peroxide (67.89%) and NO (70.64%) assays compared to its methanolic extracts of G. tenuistipitata. This study concluded that methanol as a solvent extract of brown seaweed (P. tetrastromatica) exhibited bioactivity and antioxidant potentiality which will be useful for pharmacological as well as in functional food application.

show abstract

Section: Discussionsupporting

confidence: 81%

Section: Discussionmentioning

confidence: 96%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Effect of solvents on bioactive compounds and antioxidant activity of Padina tetrastromatica and Gracilaria tenuistipitata seaweeds collected from Bangladesh

Sobuj

Islam

et al. 2021

Sci Rep

Self Cite

View full text Add to dashboard Cite

show abstract

Enhancement of cytotoxic and antioxidant activities of Digenea simplex chloroform extract using the nanosuspension technique

El-Rafie

Hasan

Zahran

2022

Bioprocess Biosyst Eng

View full text Add to dashboard Cite

Digenea simplex (D. simplex), an Egyptian marine red macroalga, contains a diverse group of phytochemicals with unique bioactivities. At the same time, the synthesis of nanosuspension (NS) has received increasing interest to optimize the technological aspects of drugs. Thence, the main objective of this work was to use the chloroform extract (ChlE) of D. simplex to prepare its nanosuspension (ChlE-NS) formulation to increase its aqueous solubility, thereby improving its bioactivity. By using FTIR, GC/MS analysis, and phytochemical screening assays, the chemical profiling of ChlE was assessed. NS was prepared by the antisolvent precipitation technique using 1.5% w/v polyvinyl alcohol (PVA). A light microscope, FTIR, particle size distribution, polydispersity index (PDI), and zeta potential (ZP) measurements was used to characterize the prepared NS. Four cancer cell lines were used in the MTT experiment to investigate the anticancer potential of ChlE and ChlE-NS. An apoptotic mechanism was established using acridine orange/ethidium bromide (AO/EB) dual staining, DNA fragmentation, and increased caspase activity. ChlE and ChlE-NS were also evaluated as antioxidants using DPPH and ABTS free radical assays. The results showed that, when compared to ChlE, ChlE-NS had greater cytotoxic activity against the four cancer cell lines. However, results of antioxidant activity showed that ChlE-NS had an IC50 of 36.86 ± 0.09 and 63.5 ± 0.47%, while ChlE had values of 39.90 ± 0.08 and 86.5 ± 0.8% in DPPH and ABTS assays, respectively. Based on the results of this research, D. simplex ChlE-NS may be an effective strategy for enhancing ChlE's cytotoxic and antioxidant activities. Graphical abstract

show abstract

Influence of roasting degrees on the antioxidant and anti-angiogenic effects of Coffea liberica

2021

View full text Add to dashboard Cite

Evaluation of bioactive chemical composition, phenolic, and antioxidant profiling of different crude extracts of Sargassum coriifolium and Hypnea pannosa seaweeds

Cited by 38 publications

References 46 publications

Effect of solvents on bioactive compounds and antioxidant activity of Padina tetrastromatica and Gracilaria tenuistipitata seaweeds collected from Bangladesh

Effect of solvents on bioactive compounds and antioxidant activity of Padina tetrastromatica and Gracilaria tenuistipitata seaweeds collected from Bangladesh

Enhancement of cytotoxic and antioxidant activities of Digenea simplex chloroform extract using the nanosuspension technique

Influence of roasting degrees on the antioxidant and anti-angiogenic effects of Coffea liberica

Contact Info

Product

Resources

About