Evaluation of Bioactive Compounds on Different Extracts of Linum Usitatissimum and Its Antimicrobial Properties against Selected Oral Pathogens

Fadzir, Ummu Afifah; Mokhtar, Khairani Idah; Mustafa, Basma Ezzat; Darnis, Deny Susanti

doi:10.7454/msk.v22i3.10181

Cited by 2 publications

(2 citation statements)

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“…According to Yoo and Jwa (2019), β-caryophyllene may improve periodontal health by reducing inflammation produced by lipopolysaccharide and neutralizing volatile sulfur compounds (VSCs). Other substances included hexadecenoic and linolenic acid, which belong to a class of fatty acids with have antimicrobial, antibacterial, and antioxidant properties (Fadzir et al, 2018;Tyagi & Agarwal, 2017).…”

Section: Gas Chromatography-mass Spectrometry (Gcms) Analysismentioning

confidence: 99%

Phytochemical and Antibacterial Screening of Chromolaena odorata Leaf Extract

Ishak,

Usaizan,

Raffi

2023

JSML

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The discovery of antibacterial drugs from natural sources as a substitute for preventing bacterial resistance has become necessary due to the increase in bacterial drug resistance. Chromolaena odorata has been reported to have antibacterial effects. Therefore, this study investigated the phytochemical components and antibacterial properties of C. odorata leaves. C. odorata leaves were collected, prepared, and extracted using a standard procedure with 95% methanol and 95% ethanol, respectively. Both extracts were subjected to phytochemical screening and Gas Chromatography-Mass Spectrometry to detect phytochemical compounds. Chromolaena odorata methanolic extract at a concentration of 50 mg/mL, 100 mg/mL, 150 mg/mL and 200 mg/mL was carried out for antibacterial screening using the agar well diffusion tested on Staphylococcus aureus (ATCC 43330), Bacillus subtilis (B29), Escherichia coli (ATCC 25922) and Pseudomonas aeruginosa (ATCC 15442). The methanolic extract was present with tannin, terpenoid, alkaloid, and saponin while ethanolic extract was present with tannin and alkaloid. The GC-MS chromatogram identified as many as 27 and 19 compounds for ethanolic and methanolic extract, respectively. The C. odorata ethanolic extract consists mainly of Phenol (0.51%), Sesquiterpenoid (20.69%) and Fatty acid (39.2%). Meanwhile, C. odorata methanolic extract consists of Sesquiterpenoid (62.26%) and Fatty acid (17.11%). Antibacterial activity of S. aureus was the highest inhibition zone diameter with 7.67 mm to 10.33 mm from 50 mg/ml to 200 mg/mL concentration of C. odorata extract. Escherichia coli and B. subtilis inhibition zones diameter was 200 mg/mL concentration of C. odorata extract. No antibacterial activities were obtained for P. aeruginosa. This study suggests that C. odorata consists of a variety of phytochemicals and contains antibacterial properties. Thus, C. odorata represents a promising natural source for antibacterial resistance drugs.

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Section: Gas Chromatography-mass Spectrometry (Gcms) Analysismentioning

confidence: 99%

Phytochemical and Antibacterial Screening of Chromolaena odorata Leaf Extract

Ishak,

Usaizan,

Raffi

2023

JSML

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“…The antimicrobial effect of various plant extracts was studied and documented (Paiva et al 2010). Incorporating essential oils from Thymus vulgaris in milk for cheese production provides an additional defence against several exogenous detrimental pathogens of dairy products (Licon et al 2020) Canada is the world's biggest producer of flax, with 38%, while the annual worldwide is 3.06 million tons (Fadzir et al 2018). The antimicrobial properties of flaxseeds were studied for their therapeutic properties (Adolphe et al 2010).…”

Section: Introductionmentioning

confidence: 99%

Short Communication: Fungicidal effect of flax seed oil against several fungal strains

MIR,

AHMAD

2023

Asian J Nat Prod Biochem

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Abstract. Mir RA, Ahmad MK. 2023. Short Communication: Fungicidal effect of flax seed oil against several fungal strains. Asian J Nat Prod Biochem 21: 1-5. The plant world is provided with innate biologically active secondary metabolites, which regulate its defense mechanism. Chemical fungicides pose a great threat to the plant kingdom regarding disease resistance and phytotoxicity. Furthermore, chemical fungicides provide a short spectrum and poor control of plant pathogens. Seed oils have a great potential to act as a natural fungicide against several plant pathogens. The aim of this study was to evaluate the in vitro antifungal activity against eight fungal strains, Mucor mucedo, Penicillium expansum, Trichoderma viride, Trichoderma harzianum, Phytophthora crocatum, Aspergillus niger, Phytophthora infestans, and Venturia inaequalis by the poisoned food method. Antifungal activity was assessed regarding the inhibition percentage of radial growth on a solid medium (Potatoes Dextrose Agar/PDA). Flaxseed oil showed the highest (100%) antifungal activity against M. mucedo at a concentration of 5 ?L/mL, while moderate (53% and 60%) antifungal activity was recorded for P. expansum, and P. crocatum. However, linseed oil showed negative results against A. niger, T. viride, and T. harzianum. Thus, the results of the present study revealed that flaxseed oil has tremendous fungicidal activity and could become an alternative to synthetic fungicides for controlling certain dreadful plant fungal diseases.

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Evaluation of Bioactive Compounds on Different Extracts of Linum Usitatissimum and Its Antimicrobial Properties against Selected Oral Pathogens

Cited by 2 publications

References 0 publications

Phytochemical and Antibacterial Screening of Chromolaena odorata Leaf Extract

Phytochemical and Antibacterial Screening of Chromolaena odorata Leaf Extract

Short Communication: Fungicidal effect of flax seed oil against several fungal strains

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