Evaluation of biological activity and in silico molecular docking studies of Acanthus ilicifolius leaf extract against four multidrug-resistant bacteria

Naher, Kamrun; Moniruzzaman, Md.; Islam, Saidul; Hasan, Abdullah Al; Paul, Gobindo Kumar; Jabin, Tabassum; Biswas, Suvro; Zaman, Shahriar; Saleh, Abu; Uddin, Md. Salah

doi:10.1016/j.imu.2022.101092

Cited by 2 publications

(1 citation statement)

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“…2 The utilization of in silico methodologies has demonstrated that the constituents present in A. ilicifolius possess the ability to operate as antibacterial agents against multidrug-resistant bacteria. 3 © 2023 the authors. This work is licensed under the Creative Commons Attribution 4.0 International License compositions including binary, ternary, and multi-component combinations.…”

Section: Introductionmentioning

confidence: 99%

D-Optimal Mixture Design in Sonication-Maceration Solvent Extraction of Total Phenolic and Antibacterial Activity from Acanthus ilicifolius Leaves

2023

TJNPR

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The antimicrobial capabilities of methanol and chloroform extracts were demonstrated through in vitro investigations, indicating its potential as antibacterial agents. 4,5 There are several additional pharmacological features associated with the substance, including its hepatoprotective, anticancer, and antidiabetic effects, which are believed to be mediated through its mechanism as a glucosidase inhibitor. [6][7][8][9] Significant amounts of bioactive chemicals can be extracted from A. ilicifolius. 6,10 It is composed of phenolic compounds like coumaric acids, for example. 11 Phenolic compounds are widely recognized in the food sector for their bio preservation properties, which encompass both antibacterial and antioxidant activities. 12 Moreover, they are increasingly being explored as a viable substitute for synthetic additives. 13,14 The extraction of these chemicals from food is an essential process in the isolation and purification of bioactive constituents. Nonetheless, the process is subject to various factors such as the choice of extraction solvents, the ratio of sample to solvent, the duration and method of extraction, as well as the physical and chemical characteristics of the sample matrix. [15][16][17] The existing research does not present a consensus regarding a singular, effective standard extraction procedure or the optimal extraction solvent. Multiple studies have found that solid-liquid extraction employing various solvents is the most efficient method, with solvents of higher polarity often exhibiting enhanced solubility of polyphenols in the extraction process. 18 In a variety of extraction techniques, isolated solvents are employed, which have been found to have suboptimal extraction outcomes. In instances of this nature, the utilization of solvent mixes is advantageous, including a range of

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Section: Introductionmentioning

confidence: 99%

D-Optimal Mixture Design in Sonication-Maceration Solvent Extraction of Total Phenolic and Antibacterial Activity from Acanthus ilicifolius Leaves

2023

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Biological activity of Mesua ferrea (Nageswar) seed extracts: An in vitro and in silico study

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Evaluation of biological activity and in silico molecular docking studies of Acanthus ilicifolius leaf extract against four multidrug-resistant bacteria

Cited by 2 publications

References 45 publications

D-Optimal Mixture Design in Sonication-Maceration Solvent Extraction of Total Phenolic and Antibacterial Activity from Acanthus ilicifolius Leaves

D-Optimal Mixture Design in Sonication-Maceration Solvent Extraction of Total Phenolic and Antibacterial Activity from Acanthus ilicifolius Leaves

Biological activity of Mesua ferrea (Nageswar) seed extracts: An in vitro and in silico study

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