Evaluation of biological activity of Diplotaenia cachrydifolia Boiss. that medicinal plant

Abstract

In a modern context, at least 25% of the active ingredients of pharmacologically produced medicines are derived from plants. In addition, the active ingredients of many synthetically produced medicines are similar to chemicals that were first isolated from medicinal plants (Berber et al. 2013). The active ingredients in medicinal plants have been shown to exhibit high biological capability (Bhouri et al. 2010; Kilani-Jaziri et al. 2011) and these plants seem to be the best resources for the discovery of novel bioactive chemicals in the design of new drugs. Recently, there has been considerable interest in the antimicrobial (Rates 2001), antioxidative (Kilani-Jaziri et al. 2011) and antigenotoxic activities (Amkiss et al. 2013) of medicinal plants. At present, alternative antimicrobial medicines are needed, in particular, for the treatment of infectious diseases. Mounting resistance of microorganisms to many antibiotics has led to increasing difficulties in the treatment of infectious diseases. In this context, local medicinal plants are known to be rich in antimicrobial properties and thus, a source of novel antimicrobials (Rates 2001; Kilani-Jaziri et al. 2011). Furthermore, some medicinal plants are reported to exhibit high antioxidant activity (Kilani-Jaziri et al. 2011), and plant phenolics are generally the source of these natural antioxidant properties (Atoui et al. 2005; Cavlak and Yagmur 2016). Antioxidants prevent the formation of free radicals produced routinely in all cells as part of their normal function; however, free radical accumulation in cells may play a role in many diseases (Young and Woodside 2001). Recently, there has been a growing interest in natural antioxidants of plant origin. Natural antioxidants obtained from medicinal plants can prevent the formation of free radicals, thus indicating their potential as novel therapeutic agents (Nogochi and Nikki 2000; Chaabane et al. 2012). Of late, considerable research has been focused on the antigenotoxic activity of medicinal

Antioxidant, Antimicrobial and Phenolic Component Analysis of Some Edge Medicinal Plants

“…The antioxidant activity was evaluated as percent inhibition. 24 Antioxidant activity by ABTS assay ABTS radical scavenging activity assay was performed using ABTS (2,2-Azino-bis (3ethylbenzothiazoline-6-sulfonic acid)) free radical according to the method reported by Miller et al (1993) 25 and developed by Re et al 26. Methanol was used as the control solvent and Trolox (500-2500 µg mL -1 , Aldrich) was used as a standard compound. 27 Trolox is a water-soluble analog of vitamin E. Studies were repeated twice.…”

“…The antioxidant activity was evaluated as percent inhibition. 24,27 Evaluation of total phenolic component The total phenolic content of the plants extracts was determined with the Folin-Ciocalteu reagent. The amounts of phenolic compounds corresponding to the gallic acid standard of the extracts were determined in the study.…”