2015
DOI: 10.1002/elps.201500294
|View full text |Cite
|
Sign up to set email alerts
|

Evaluation of biological activity of quantum dots in a microsystem

Abstract: The presented work aimed at systematic investigation of biological activity of CdSex S1- x /ZnS and CdSe/ZnS quantum dots (QDs), whose surface was modified with different ligands. For these studies, we used a microfluidic system combined with fluorescence microscopy techniques, which enabled analysis of cells' morphology, viability, and QDs uptake. PDMS and glass-based microfluidic system enabled the precise control of the cell environment, allowed to examine five replications of each tested QDs concentrations… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
4
0

Year Published

2016
2016
2022
2022

Publication Types

Select...
4
4

Relationship

0
8

Authors

Journals

citations
Cited by 11 publications
(4 citation statements)
references
References 31 publications
0
4
0
Order By: Relevance
“…Researchers have used QDs based microfluidic systems in combination with biological imaging techniques for cytotoxicity studies [114]. A group used QD-IgG conjugates in combination with microfluidic protein chip for cancer detection and found that microfluidic systems improve the detection limit and sensitivity improves up to four orders in magnitude as compared to organic dyes [115].…”
Section: Quantum Dots As a Microsystems: Implication To Poctmentioning
confidence: 99%
“…Researchers have used QDs based microfluidic systems in combination with biological imaging techniques for cytotoxicity studies [114]. A group used QD-IgG conjugates in combination with microfluidic protein chip for cancer detection and found that microfluidic systems improve the detection limit and sensitivity improves up to four orders in magnitude as compared to organic dyes [115].…”
Section: Quantum Dots As a Microsystems: Implication To Poctmentioning
confidence: 99%
“…It was shown that, 3-mercaptobenzoic acid (3MBA) molecules form stable bonds with metal nanoparticles [17,18]. Long-chain 6-mercaptohexanoic acid (6MHA) molecule may bind to nanocrystals (including Cdbased alloyed QDs), showing not only the improvement of optical quality and stability, but also a decrease in toxicity of QDs in biological environment [19]. 6MHA and 11-mercaptoundecanoic acid (11MUA) molecules were both successfully used in complex formation of QDs and TiO 2 nanoparticles [20].…”
Section: Synthesis Of Qd and Gold Nanoparticlesmentioning
confidence: 99%
“…All solutions of QDs were solubilized in water with the use of biphasic phase transfer protocol, based on the previously described procedures for thiolated ligands (Grabowska-Jadach et al 2016b;Liu et al 2007;Tamang et al 2011). CdSe x S 1−x /ZnS coreshell QDs solution in toluene was centrifuged with the fourfold aliquot of anhydrous ethanol (RCF 18,187×g, 15 min) and the pellet was resuspended in chloroform prior to ligand exchange.…”
Section: Ligand Exchangementioning
confidence: 99%