2023
DOI: 10.3390/jfb14060300
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Evaluation of Biomedical Applications for Linseed Extract: Antimicrobial, Antioxidant, Anti-Diabetic, and Anti-Inflammatory Activities In Vitro

Abstract: Background: In the last few decades, the development of multidrug-resistant (MDR) microbes has accelerated alarmingly and resulted in significant health issues. Morbidity and mortality have increased along with the prevalence of infections caused by MDR bacteria, making the need to solve these problems an urgent and unmet challenge. Therefore, the current investigation aimed to evaluate the activity of linseed extract against Methicillin-resistant Staphylococcus aureus (MRSA) as an isolate from diabetic foot i… Show more

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Cited by 9 publications
(8 citation statements)
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“…aureus 4G6D protein and chlorogenic acid, the primary chemical found in the flaxseed extract, inhibited the 4HI0 protein. A low energy score (−6.26841 kcal/mol) was obtained with particular residues (PRO 38, LEU 3, LYS 195, and LYS 2) from the molecular docking interaction …”
Section: Resultsmentioning
confidence: 99%
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“…aureus 4G6D protein and chlorogenic acid, the primary chemical found in the flaxseed extract, inhibited the 4HI0 protein. A low energy score (−6.26841 kcal/mol) was obtained with particular residues (PRO 38, LEU 3, LYS 195, and LYS 2) from the molecular docking interaction …”
Section: Resultsmentioning
confidence: 99%
“…A low energy score (−6.26841 kcal/mol) was obtained with particular residues (PRO 38, LEU 3, LYS 195, and LYS 2) from the molecular docking interaction. 35 …”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…The RCSB protein data repository included urate oxidase and H. pylori urease crystalline structures for virtual screening ( Alawlaqi et al, 2023 ; Jabeen et al, 2023 ) (1R4U and 4HI0). Molecules were docked using MGLTools, AutoDock4, and Autogrid4 binary files ( Morris et al., 2009 ).…”
Section: Developed Methods and Materialsmentioning
confidence: 99%
“…By implementing the 2,2-diphenyl-1-picrylhydrazyl (DPPH) method, the ability of nanoparticles to scavenge radicals was determined according to Alawlaqi et al (2023) with some modification. A 0.1 mM DPPH suspension was created with 95% ethanol as the solvent, which was added to various ZnO-NPs concentrations (from 7.81 to1000 μg mL -1 ) to begin a reaction.…”
Section: Antioxidant Activity Of Zno-npsmentioning
confidence: 99%