2022
DOI: 10.1002/bdd.2332
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Evaluation of bleeding and anticoagulation markers by edoxaban and low‐dose cyclosporine: A case series study

Abstract: It was reported that high‐dose cyclosporine at 500 mg daily increases edoxaban exposure. We investigated whether cyclosporine <500 mg daily leads to edoxaban‐induced bleeding in the clinical setting. This case series study included patients receiving edoxaban and cyclosporine at Mie University Hospital. The outcomes were bleeding and anticoagulant markers, including activated partial thromboplastin time (APTT), prothrombin time (PT), and the international normalized ratio of prothrombin time (PT‐INR). We exami… Show more

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