Evaluation of blood lead levels in opium addicts and healthy control group using novel deep eutectic solvent based dispersive liquid–liquid microextraction followed by GFAAS

Jouybari, Touraj Ahmadi; Jouybari, Hadi Ahmadi; Hosseini, Fatemeh; Nesari, Mohsen; Fattahi, Nazir

doi:10.1007/s11356-022-23942-5

Cited by 14 publications

(6 citation statements)

References 38 publications

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“…Next, the solution was centrifuged for 3 min at a speed of 5000 rpm so that the extractant phase (undecanol) floats. The test tube was placed in the freezer for a few minutes to freeze the undecanol, and we transferred it to a clean vial with a small spoon to re-melt at room temperature [ 35 , 36 ]. Finally, after injecting into the ICP-MS device, the level of the heavy metals under investigation was measured.…”

Section: Methodsmentioning

confidence: 99%

Trace element levels: How Substance Use Disorder (SUD) contributes to the alteration of urinary essential and toxic element levels

Mansouri,

Azadi,

Drebadami

et al. 2024

PLoS ONE

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Increasing illicit drug use is one of the main problems in most countries or societies. Monitoring heavy metals and trace elements in this vulnerable group seems to be necessary. Therefore, we assessed the urinary trace element and toxic metals/metalloids concentrations (Zinc (Zn), Iron (Fe), Copper (Cu), Chromium (Cr), Lead (Pb), Cadmium (Cd), Arsenic (As), Nickel (Ni), and Mercury (Hg)) in opium, tramadol, and cannabis users compared to healthy subjects. In this cross-sectional study, patients with substance use disorder (SUD) (n = 74) were divided into four groups: cannabis, tramadol, opium, and mixed (simultaneous use of more than one of the three studied substances), along with a healthy group (n = 60). Urine samples were prepared by dispersive liquid-liquid microextraction method so that heavy metals/metalloids could be measured by ICP-MS. The mean urinary concentration of Cu (48.15 vs. 25.45; 89.2%, p<0.001), Hg (1.3 vs. 0.10; 1200%, p < 0.001), and Zn (301.95 vs. 210; 43.8%, p < 0.001) was markedly lower among patients with SUD. The mean urinary concentration of other elements including As (1.9 vs. 4.1; 115.8%), Cd (0.1 vs. 1.10; 1000%), Cr (6.80 vs. 11.65; 71.3%), Ni (2.95 vs. 4.95; 67.8%), and Pb (1.5 vs. 7.9; 426.6%) were significantly higher among patients with SUD compared to healthy subjects. When sub-groups were compared, no significant differences were observed between their trace element levels (Kruskal-Wallis test, p > 0.05). This can be an indication that regardless of the type of drug, the levels of trace elements are changed with respect to healthy individuals. Our results showed that illicit drug use causes changes in urinary trace element/heavy metal/metalloid levels and highlights the need for monitoring heavy metals and trace elements in individuals with substance use disorder. Assessment of different elements in biological samples of drug dependents may be useful for implementing new prevention and treatment protocols. In case of changes in their levels, complementary recommendations, attention to diet, and periodic assessment of toxic metal levels within treatment programs will be needed.

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Section: Methodsmentioning

confidence: 99%

Trace element levels: How Substance Use Disorder (SUD) contributes to the alteration of urinary essential and toxic element levels

Mansouri,

Azadi,

Drebadami

et al. 2024

PLoS ONE

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“…The constituent components of DESs and their molar ratio, abbreviations of DESs and relevant references are collected in Table 1. The synthesized DESs are as follows: choline chloride : decanoic acid with a molar ratio of 1 : 1 (DES-I), 16 menthol : p -aminophenol with a molar ratio of 1 : 2 (DES-II), 17 l -menthol : SA, with a molar ratio of 4 : 1 (DES-III), 18 l -menthol : CSA, with a molar ratio of 5 : 1 (DES-IV), 19 TBAC : p -aminophenol with a molar ratio of 1 : 2 (DES-V), 24 and thymol : decanoic acid with a molar ratio of 1 : 2 (DES-VI). 25…”

Section: Methodsmentioning

confidence: 99%

“…16,17 Nowadays, deep eutectic solvents (DESs) have been acknowledged as a new class of green solvents which may replace traditional organic solvents in DLLME. 18,19 While preparing DESs, a mixture of two compounds, which are a hydrogen bond acceptor (HBA) and hydrogen bond donor (HBD), is used. 20,21 Two different compounds with HBA and HBD properties have high melting points in their pure form.…”

Section: Introductionmentioning

confidence: 99%

Extraction and determination of aflatoxin B1 in cereal samples using pH-switchable hydrophobic deep eutectic solvents followed by HPLC-FL analysis

Ameen

Al-Masri

2023

Anal. Methods

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“…Conventional elemental analysis techniques like inductively coupled plasma-optical emission spectrometry (ICP-OES), [8,9] ICPmass spectrometry (ICP-MS), [10][11][12] flame atomic absorption spectrometry (FAAS) [7,13,14] and graphite furnace atomic absorption spectrometry (GFAAS) [15,16] have been widely used for heavy metal determination. Even though FAAS is the most regularly used heavy metal detection system among these methods, the system sensitivity is insufficient to detect trace and ultra-trace levels of heavy metals.…”

Section: Introductionmentioning

confidence: 99%

Synthesis of Nanocube‐Shaped Cobalt Tin Hydroxides for the Preconcentration of Lead in Environmental Seawater Collected from Antarctic Region

Şaylan,

Ayyıldız,

Zaman

et al. 2024

ChemistrySelect

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Here, a simple/efficient analytical strategy based on dispersive solid phase extraction was developed using CoSn(OH)6 nanocubes for lead ions from environmental water samples by FAAS (flame atomic absorption spectrometry). CoSn(OH)6 was synthesized as an adsorbent using the co‐precipitation method and characterized. The characterization studies proved the cube‐shaped morphology and uniform size distribution. The optimal experimental conditions were found by optimization studies and, the limit of quantification (LOQ), limit of detection (LOD), linear dynamic range were recorded as 37.6 μg/L, 11.3 μg/L, and 40–600 μg/L, respectively. The enhancement factor of the presented method was calculated as 158.7‐folds compared to the LOD of the conventional FAAS system. Recovery experiments were performed to check the method's applicability/accuracy and the percent recovery results varied from 89.0 % to 112.9 %. According to these findings, the developed method was successfully applied for the quantitative determination of the target analyte in a seawater sample matrix.

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Evaluation of blood lead levels in opium addicts and healthy control group using novel deep eutectic solvent based dispersive liquid–liquid microextraction followed by GFAAS

Cited by 14 publications

References 38 publications

Trace element levels: How Substance Use Disorder (SUD) contributes to the alteration of urinary essential and toxic element levels

Trace element levels: How Substance Use Disorder (SUD) contributes to the alteration of urinary essential and toxic element levels

Extraction and determination of aflatoxin B1 in cereal samples using pH-switchable hydrophobic deep eutectic solvents followed by HPLC-FL analysis

Synthesis of Nanocube‐Shaped Cobalt Tin Hydroxides for the Preconcentration of Lead in Environmental Seawater Collected from Antarctic Region

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