“…In previous transmission analysis studies, the ion-chamber energy response was roughly approximated by one of the following three methods: (1) assuming that the material of the chamber wall and buildup cap are air-equivalent, thus the aircavity dose, D cav , equals the collision air-kerma, K air col , and consequently, R(d, E) is proportional to ðl en =qÞ air , the mass energy absorption coefficient for air; 16,17,23,24,26,31,32 (2) measuring the response at a few known low energies (e.g., 137 Cs and 60 Co) then interpolating or extrapolating to other energies; [4][5][6][11][12][13] or, (3) developing approximate expressions to take into account the deviation from air equivalence caused by the wall and/or cap materials. 8,14,27 To the authors' knowledge, no previous study on transmission analysis used Monte Carlo for detailed detector modeling.…”