Evaluation of Brown and red seaweeds-extracts as a novel larvicidal agent against the deadly human diseases-vectors, Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus

Aravinth, Annamalai; Dhanasundaram, Sundaramoorthy; Perumal, Pachiappan; Kamaraj, Chinnaperumal; Khan, Safir Ullah; Ali, Amir; Ragavendran, Chinnasamy; Amutha, Vadivel; Rajaram, Rajendran; Santhanam, Perumal; Luna-Arias, Juan Pedro; Mashwani, Zia-ur-Rehman

doi:10.1016/j.exppara.2023.108651

Experimental Parasitology

2024

DOI: 10.1016/j.exppara.2023.108651

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Evaluation of Brown and red seaweeds-extracts as a novel larvicidal agent against the deadly human diseases-vectors, Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus

Annamalai Aravinth,

Sundaramoorthy Dhanasundaram,

Pachiappan Perumal

et al.

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Cited by 2 publications

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Larvicidal potential of ether extract, and its derivatives fatty acids, and fatty acid methyl esters from Tecoma stans seeds: Bioprospecting for an effective insecticide

Azevedo,

Gonçalves,

Coimbra

et al. 2024

Journal of Natural Pesticide Research

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Larvicidal potential of ether extract, and its derivatives fatty acids, and fatty acid methyl esters from Tecoma stans seeds: Bioprospecting for an effective insecticide

Azevedo,

Gonçalves,

Coimbra

et al. 2024

Journal of Natural Pesticide Research

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Hypoglycemic Properties of Leccinum scabrum Extracts—An In Vitro Study on α-Glucosidase and α-Amylase Inhibition and Metabolic Profile Determination

Ferraro,

Spagnoletta,

Rotondo

et al. 2024

JoF

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Type-2 diabetes affects an increasing percentage of the world’s population and its control through dietary management, involving the consumption of health-promoting foods or their derived supplements, is a common strategy. Several mushroom species have been demonstrated to be endowed with antidiabetic properties, resulting from their ability in improving insulin sensitivity and production, or inhibiting the carbohydrate-hydrolyzing enzymes α-amylase and α-glucosidase. This study aimed to investigate for the first time the hypoglycemic properties of the edible mushroom Leccinum scabrum (Bull.) Gray. Mushroom extracts were prepared through the microwave-assisted extraction (MAE) technique using green solvents with different polarity degrees. The inhibition activity of all the obtained extracts on both α-glucosidase and α-amylase was evaluated and the highest activity was observed for the EtOAc extract which showed an IC50 value about 60-fold lower than the reference compound 1-deoxynojirimycin (DNJ) on α-glucosidase (0.42 ± 0.02 and 25.4 ± 0.6 µg/mL, respectively). As expected on the basis of the literature data concerning both α-glucosidase and α-amylase inhibition, a milder inhibition activity on pancreatic α-amylase was observed. Preliminary in vivo tests on Drosophila melanogaster carried out on the most active obtained extract (EtOAc) confirmed the in vitro observed hypoglycemic activity. Finally, the EtOAc extract metabolic profile was determined through GC-MS and HRMS analyses.

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Evaluation of Brown and red seaweeds-extracts as a novel larvicidal agent against the deadly human diseases-vectors, Anopheles stephensi, Aedes aegypti and Culex quinquefasciatus

Cited by 2 publications

References 36 publications

Larvicidal potential of ether extract, and its derivatives fatty acids, and fatty acid methyl esters from Tecoma stans seeds: Bioprospecting for an effective insecticide

Larvicidal potential of ether extract, and its derivatives fatty acids, and fatty acid methyl esters from Tecoma stans seeds: Bioprospecting for an effective insecticide

Hypoglycemic Properties of Leccinum scabrum Extracts—An In Vitro Study on α-Glucosidase and α-Amylase Inhibition and Metabolic Profile Determination

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