Evaluation of capsule endoscopy in active, mild-to-moderate, overt, obscure GI bleeding

Apostolopoulos, Periklis; Liatsos, Christos; Gralnek, Ian M.; Kalantzis, C.; Giannakoulopoulou, Eleftheria; Alexandrakis, Georgios; Tsibouris, Panagiotis; E, Kalafatis; Kalantzis, Nikolaos

doi:10.1016/j.gie.2007.06.058

Cited by 84 publications

(62 citation statements)

References 27 publications

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“…Thus, implementation of an aggressive management to detect and treat the underlying bleeding lesion is encouraged. This finding was also supported by other studies (19,34,48,49). In the Ribeiro et al study (27), more than half of patients with positive VCE received specific treatment, thus decreasing the rebleeding risk.…”

Section: Impact On Subsequent Therapeutic Strategies and Clinical Outsupporting

confidence: 68%

Long-term effects of video capsule endoscopy in the management of obscure gastrointestinal bleeding

et al. 2017

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Obscure gastrointestinal bleeding (OGIB) accounts for approximately 5% of all gastrointestinal (GI) hemorrhages. It usually arises from a small bowel lesion beyond the reach of conventional endoscopy including esophagogastroduodenoscopy and colonoscopy. Video capsule endoscopy (VCE) revolutionized the evaluation of OGIB patients since it allows reliable and noninvasive visualization of the small bowel mucosal surface. Since 2001, VCE has evolved into an efficient technology integrated in clinical practice. It is the cornerstone in the algorithm of OGIB investigation given its high diagnostic yield, which compares favorably to that of double-balloon enteroscopy (DBE). In terms of outcomes, a positive index VCE examination usually correlates to a high re-bleeding rate, while a negative one provides adequate evidence of low re-bleeding risk, suggesting a wait and watch approach in this subset of patients. Additionally, a variety of factors has been acknowledged as significant predictors of re-bleeding episodes. While research data regarding immediate endoscopic findings have matured, data concerning the clinical utility of VCE in patients with OGIB on the long-term remain sparse. This manuscript reviews the current literature, aiming to highlight the role of VCE in the long-term management of OGIB.

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Section: Impact On Subsequent Therapeutic Strategies and Clinical Outsupporting

confidence: 68%

Long-term effects of video capsule endoscopy in the management of obscure gastrointestinal bleeding

et al. 2017

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“…CE enables direct visualisation of the small bowel mucosa and has a high sensitivity for detecting flat lesions, such as angiodysplasias, ulcers and arteriovenous malformations which are not easily detectable on radiological modalities [15] . The reported diagnostic yield in literature ranges from 58.4% to 86.8% [9,14,[16][17][18][19][20][21] . The wide range is attributable to different definitions of a positive finding on CE.…”

Section: Capsule Endoscopymentioning

confidence: 99%

Evaluation and outcomes of patients with obscure gastrointestinal bleeding

Santhakumar

Liu

2014

WJGP

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Core tip: This article examines the role of current diagnostic modalities for the investigation of obscure gastrointestinal bleeding (OGIB) and outcomes in patients undergoing these investigations. Capsule endoscopy and double balloon enteroscopy remain the cornerstone of diagnostic and therapeutic management. The diagnostic and therapeutic capabilities of certain modalities are influenced by the nature of bleeding in OGIB. Longterm outcome data in patients with OGIB is limited but is most promising for capsule endoscopy.Santhakumar C, Liu K. Evaluation and outcomes of patients with obscure gastrointestinal bleeding. World J Gastrointest Pathophysiol 2014; 5(4

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“…In these studies, CECR are variable and lower than what we note in our study. In a prospective European study of only mild to moderate obscure overt GI bleeders, incomplete IP CEs were 21.6%, but in 75% of the incomplete exams there was some localization of the bleed site [9] . However, this study excluded all severe bleeders and inpatients with other indications.…”

Section: Discussionmentioning

confidence: 92%

Inpatient Capsule Endoscopy Leads to Frequent Incomplete Small Bowel Examinations

Oosterveen¹,

Rahimi²,

Losurdo³

et al. 2006

Gastrointestinal Endoscopy

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Evaluation of capsule endoscopy in active, mild-to-moderate, overt, obscure GI bleeding

Cited by 84 publications

References 27 publications

Long-term effects of video capsule endoscopy in the management of obscure gastrointestinal bleeding

Long-term effects of video capsule endoscopy in the management of obscure gastrointestinal bleeding

Evaluation and outcomes of patients with obscure gastrointestinal bleeding

Inpatient Capsule Endoscopy Leads to Frequent Incomplete Small Bowel Examinations

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