Evaluation of cardiac autonomic functions in Children with Thalassemia Trait, Iron Deficiency Anemia and Iron Deficiency

Çetin, Mecnun; Moumin, Nichal; Karaboğa, Bertan; Coşkun, Şenol; Gülen, Hüseyin

doi:10.5505/ejm.2018.17363

Cited by 1 publication

(1 citation statement)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Increased QT dispersion in hemophilia children increases the risk of their exposure to dysrhythmia and sudden death, the normal range of QT dispersion value is 10-70 ms with mean 29 ± 26 ms in early age [15]. [23].…”

Section: Resultsmentioning

confidence: 99%

Untitled

2023

J. Med. Chem. Sci.

View full text Add to dashboard Cite

Background: Hemophilia-A is a sex-related hereditary bleeding disorder, like the general populations, mortality from cardiovascular diseases is currently responsible for one-third of deaths in hemophilia patients. Method: A case controlled study was carried out on fifty children; twenty five male with hemophilia-A compared to twenty five healthy male children.12 lead surface ECG, 24 hour holter monitoring and basic echocardiography assessment were done for all participating children. Results: ECG recording revealed that increased heart rate (b/min), QTc/msec, the maximum and QT dispersion in the hemophilia children vs. the control, increased QT dispersion by 24 hour holter in hemophilia children. Reduced time domain parameters for HRV (ms) in hemophilia children were compared to the healthy controls. A significant difference was observed between the diseased and healthy group in the number and frequency of the subject with increased QTc dispersion more than 70 ms detected by ECG, but not by holter. Conclusion:There was an increase in QT dispersion in children with hemophilia that put them at risk for developing dysrhythmia, sympathyvagal imbalance detected by the presence of depressed HRV, and also exposed them to cardiac morbidities and sudden cardiac death.

show abstract

Section: Resultsmentioning

confidence: 99%

Untitled

2023

J. Med. Chem. Sci.

View full text Add to dashboard Cite

show abstract

Evaluation of cardiac autonomic functions in Children with Thalassemia Trait, Iron Deficiency Anemia and Iron Deficiency

Cited by 1 publication

References 26 publications

Untitled

Untitled

Contact Info

Product

Resources

About