Evaluation of Cardiac Cone–Beam Single Photon Emission Computed Tomography Using Observer Performance Experiments and Receiver Operating Characteristic Analysis

Tsui, B.M.W.; Terry, James A.; Gullberg, Grant T.

doi:10.1097/00004424-199312000-00004

Cited by 117 publications

(34 citation statements)

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“…The 4D Dynamic MCAT phantom [5][6][7][8] was developed to permit study of the effects of anatomical variations on cardiac SPECT images [9] and study of gated SPECT [7,10]. Unfortunately, it is limited in its ability to realistically model anatomical variations and patient motion.…”

Section: Introductionmentioning

confidence: 99%

Modeling respiratory mechanics in the MCAT and spline-based MCAT phantoms

Segars

Lalush

Tsui³

2001

IEEE Trans. Nucl. Sci.

211

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Respiratory motion can cause artifacts in myocardial SPECT. We incorporate respiratory mechanics into the current 4D MCAT and into the next generation spline-based MCAT phantoms. In order to simulate respiratory motion in the current MCAT phantom, the geometric solids for the diaphragm, heart, ribs, and lungs were altered through manipulation of parameters defining them. Affine transformations were applied to the control points defining the same respiratory structures in the spline-based MCAT phantom to simulate respiratory motion. The NURBS surfaces for the lungs and body outline were constructed in such a way as to be linked to the surrounding ribs. Expansion and contraction of the thoracic cage then coincided with expansion and contraction of the lungs and body. The changes both phantoms underwent were splined over time to create time continuous 4D respiratory models. We conclude that both respiratory models are effective tools for researching effects of respiratory motion.

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Section: Introductionmentioning

confidence: 99%

Modeling respiratory mechanics in the MCAT and spline-based MCAT phantoms

Segars

Lalush

Tsui³

2001

IEEE Trans. Nucl. Sci.

211

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“…The Mathematical Cardiac Torso (MCAT) phantom is an anthropomorphic phantom, developed at the University of North Carolina that models size, shape and configurations of the major thoracic structures and organs by using of mathematical formulae (Tsui, 1993). A set of experiments was performed with two-dimensional images obtained from manipulations -adding and mirroring -of MCAT images.…”

Section: Methodsmentioning

confidence: 99%

Identification of Structures in Medical Images

Rebelo¹,

Furuie²,

Moura³

et al. 2011

Medical Imaging

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“…Existing models fall into two groups: geometrybased and voxel-based. Geometry-based phantoms [3][4][5] are derived from simple equations. The main advantage of this type is that different anatomical variations and images can be generated at multiple resolutions.…”

Section: Introductionmentioning

confidence: 99%

Dynamic model of the left ventricle for use in simulation of myocardial perfusion SPECT and gated SPECT

et al. 2003

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Simulation is a useful tool in cardiac SPECT to assess quantification algorithms. However, simple equation-based models are limited in their ability to simulate realistic heart motion and perfusion. We present a numerical dynamic model of the left ventricle, which allows us to simulate normal and anomalous cardiac cycles, as well as perfusion defects. Bicubic splines were fitted to a number of control points to represent endocardial and epicardial surfaces of the left ventricle. A transformation from each point on the surface to a template of activity was made to represent the myocardial perfusion. Geometry-based and patient-based simulations were performed to illustrate this model. Geometry-based simulations modeled ͑1͒ a normal patient, ͑2͒ a well-perfused patient with abnormal regional function, ͑3͒ an ischaemic patient with abnormal regional function, and ͑4͒ a patient study including tracer kinetics. Patient-based simulation consisted of a left ventricle including a realistic shape and motion obtained from a magnetic resonance study. We conclude that this model has the potential to study the influence of several physical parameters and the left ventricle contraction in myocardial perfusion SPECT and gated-SPECT studies.

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Evaluation of Cardiac Cone–Beam Single Photon Emission Computed Tomography Using Observer Performance Experiments and Receiver Operating Characteristic Analysis

Cited by 117 publications

References 0 publications

Modeling respiratory mechanics in the MCAT and spline-based MCAT phantoms

Modeling respiratory mechanics in the MCAT and spline-based MCAT phantoms

Identification of Structures in Medical Images

Dynamic model of the left ventricle for use in simulation of myocardial perfusion SPECT and gated SPECT

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