Evaluation of cardiovascular risk factors and bone mineral density in post menopausal women undergoing coronary angiography

Low bone mineral density is not associated with angiographically determined coronary atherosclerosis in men

“…A similar result was found by Varma et al in a study which included only women with suspected osteoporosis or osteopenia [44]. Tekin and coworkers in contrast found no association between low BMD and angiographically determined CAD in women undergoing coronary angiography [27]. Importantly, even though the majority of angiographied coronary patients are men [33,45], no previous study addressed the association of low BMD with angiographically determined coronary atherosclerosis in men.…”

“…Data on the association of low BMD and angiographically determined CAD in women are sparse and conflicting [26,27]. Of note, even though male gender is an important risk factor for CAD [28], and even though low BMD in men is associated with increased mortality from cardiovascular disease [22], no data at all are available on the association between BMD and angiographically characterized coronary atherosclerosis in men.…”

Calcium Homeostasis and Skeletal Integrity in Individuals with Familial Hypercholesterolemia and Aortic Calcification

“…A few studies reported a direct relation between increased serum triglyceride levels and higher BMD (15,16 ), while an inverse relationship between cholesterol and BMD was shown by others (17 ). A correlation between osteoporosis and cardiovascular disease has been made previously (16, 18 -20 ), while other studies did not identify a relation between conventional cardiovascular risk factors and osteoporosis (21 ). Interestingly, the magnitude of bone loss was related to aortic calcification in some studies (18, 20 -23 ), and aortic calcification was attributed to cardiovascular risk factors in 30 other studies (24 ).…”

“…Mean serum creatinine (SD) was 83 (21) mol/L, and none of the patients had a creatinine concentration Ͼ130 mol/L. Estimated GFR (SD) using the MDRD formula was 84 (21) …”

Carotid intima-media thickness and bone turnover: the role of C-terminal telopeptide of type I collagen

“…Common mechanisms and risk factors, including aging [5], cigarette smoking, estrogen deficiency, renal failure [6], chronic inflammation and oxidative stress [7], have been suggested. Vitamin D deficiency, defined as serum 25(OH)D levels \30 ng/mL, is very common, especially in the elderly, and can worsen osteoporosis and increase cardiovascular risk [8].…”