Evaluation of Carotid Intima‐Media Thickness and Aortic Elasticity in Patients with Nondipper Hypertension

Abstract

In our study, we showed that impairment of aortic elasticity parameters and increase in CIMT as a predictor of end organ damage were more often in the nondipper hypertensive patients.

Nondipping pattern and carotid atherosclerosis

“…Publication bias was assessed by using the funnel plot method. Table 1 [ [16][17][18][19][20][21][22][23][24][25][26][27][28] shows the main characteristics of analyzed studies, including clinical setting, sample size, mean age, sex distribution, mean BMI, office SBP and DBP, mean 24 h, daytime and night-time BP values in nondipping individuals.…”

“…Five studies had a score of 4 [20,22,23,27,28], six studies had a score of 5 points [16,18,19,21,24,25] and two studies had a score of 6 points [17,26]. Interobserver reproducibility in evaluating the quality of studies was 91%.…”

“…After the initial screening of titles and abstracts, 190 studies were excluded as they did not address the relation of nondipping with carotid damage and 70 were reviewed; of these, 13 studies fulfilled the inclusion and exclusion criteria and contained sufficient clinical and carotid ultrasonographic data to be included in the final review [16][17][18][19][20][21][22][23][24][25][26][27][28] (Fig. 1).…”

“…Of note, the vast majority of the population (82.3%) was examined in Europe. Ten out of 13 studies included untreated [16][17][18]21,23,24,26,28] and treated [22,27] essential hypertensive individuals. Three studies were conducted in population-based samples [19,20,25].…”

“…Individuals were defined as nondipping when nighttime SBP and DBP (seven studies), SBP [19,20,25,28] and/or mean BP [23,27] decreased less than 10% compared with daytime values.…”