Evaluation of Cerebral Blood Flow Dynamics in Transient Ischemic Attacks Patients with Fast Cine Phase Contrast Magnetic Resonance Angiography

Wang, Yuzhao; Duo, Gao; Liu, Huaijun

doi:10.1155/2020/4097829

Cited by 3 publications

(6 citation statements)

References 10 publications

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“…The study indicated that intracranial MRA combined with CU have high application value in the diagnosis of CI, and can effectively clarify vascular stenosis and hemodynamic characteristics of patients with CI. Wang et al 16 found that MRA examination can effectively characterize cerebral hemodynamic status in patients with cerebral ischemia. MRA allows to image arteries that are unreachable by a catheter approach, and the acquired images can be used to create specific cross-sectional views in the direction of choice.…”

Section: Discussionmentioning

confidence: 99%

“…This allows to clearly observe changes in the outer wall and lumen of blood vessels, and to present the distribution of atherosclerotic plaques, determine their size, and accurately evaluate the condition of carotid artery stenosis. 16 , 17 98 normal subjects and 106 TIA patients who underwent MRI examination within 72 h after the last symptom onset including the DWI sequence to exclude acute cerebral infarction were enrolled. The blood flow of the cranial total, the area of the internal carotid artery and vertebral artery, the average velocity, and the average blood flow were obtained and compared in normal subjects and TIA group.…”

Section: Discussionmentioning

confidence: 99%

“…The study indicated that intracranial MRA combined with CU have high application value in the diagnosis of CI, and can effectively clarify vascular stenosis and hemodynamic characteristics of patients with CI. Wang et al 16 98 normal subjects and 106 TIA patients who underwent MRI examination within 72 h after the last symptom onset including the DWI sequence to exclude acute cerebral infarction were enrolled. The blood flow of the cranial total, the area of the internal carotid artery and vertebral artery, the average velocity, and the average blood flow were obtained and compared in normal subjects and TIA group.…”

Section: Discussionmentioning

confidence: 99%

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The evaluation value of intracranial magnetic resonance angiography combined with carotid ultrasound in cerebral infarction

Guo,

Sun

2024

Pak J Med Sci

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Objective: To explore the evaluation value of intracranial magnetic resonance angiography (MRA) combined with carotid ultrasound (CU) in patients with cerebral infarction (CI). Methods: A retrospective analysis was conducted on 122 patients with CI who underwent intracranial MRA combined with CU examination in Shengzhou People’s Hospital from January 2021 to October 2022. Vascular stenosis rate and CU parameters of patients with different degrees of nerve damage (ND) and size of CI lesion were analyzed. Results: The rate of vascular stenosis and ultrasound parameters significantly varied between patients with different degrees of ND and different sizes of CI lesion. Spearman test showed a significant positive correlation between vascular stenosis, pulsatile index (PI), and resistance index (RI) with the degree of ND and the size of CI lesions in patients. There was a significant negative correlation between peak systolic velocity (PSV) and end-diastolic velocity (EDV) and the degree of ND and the size of CI lesions (P<0.05). Conclusions: Intracranial MRA combined with CU can clarify the vascular stenosis and hemodynamic characteristics of patients with CI, and the combined approach closely correlates with the characteristics of CI, which can be used for disease assessment. doi: https://doi.org/10.12669/pjms.40.6.9312 How to cite this: Guo X, Sun L. The evaluation value of intracranial magnetic resonance angiography combined with carotid ultrasound in cerebral infarction. Pak J Med Sci. 2024;40(6):1140-1145. doi: https://doi.org/10.12669/pjms.40.6.9312 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…The study indicated that intracranial MRA combined with CU have high application value in the diagnosis of CI, and can effectively clarify vascular stenosis and hemodynamic characteristics of patients with CI. Wang et al 16 98 normal subjects and 106 TIA patients who underwent MRI examination within 72 h after the last symptom onset including the DWI sequence to exclude acute cerebral infarction were enrolled. The blood flow of the cranial total, the area of the internal carotid artery and vertebral artery, the average velocity, and the average blood flow were obtained and compared in normal subjects and TIA group.…”

Section: Discussionmentioning

confidence: 99%

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The evaluation value of intracranial magnetic resonance angiography combined with carotid ultrasound in cerebral infarction

Guo,

Sun

2024

Pak J Med Sci

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“…These findings align with the hemodynamic changes observed prior to TIA infarction ( 6 ) and are consistent with previous reports. Additionally, the majority of TIA patients exhibited varying degrees of vascular stenosis or occlusion ( 22 ). Analysis of the best CTA images obtained through WB-CTP examination in these patients identified 278 responsible vessels.…”

Section: Discussionmentioning

confidence: 99%

Predictive value of whole-brain CT perfusion combined with ABCD3 score for short-term secondary cerebral infarction after TIA

Liu,

Chen,

2023

Front. Neurol.

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ObjectiveTo investigate the predictive value of Whole Brain CT Perfusion (WB-CTP) combined with the ABCD3 score in patients with transient ischemic attack (TIA).MethodsA total of 336 TIA patients with TIA underwent WB-CTP and ABCD3 score assessment within 48 h of admission. Spearman correlation test was performed to analyze the relationship between the degree of vascular stenosis, relative perfusion values, and ABCD3 score. Logistic regression analysis was used to identify independent risk factors for secondary cerebral infarction. Receiver operating characteristic (ROC) curves were generated to evaluate the predictive value of relative cerebral blood flow (rCBF), degree of vascular stenosis, ABCD3 score, and the WB-CTP-ABCD3 combined model for secondary cerebral infarction after TIA. Calibration curves and H-L tests were used to evaluate the predictive efficacy of the model.ResultsAmong the 336 TIA patients, 143 showed abnormal perfusion areas and 146 had responsible vessel stenosis. The degree of vascular stenosis, relative time-to-maximum (rTmax), and relative mean transit time (rMTT) were positively correlated with the ABCD3 score, while rCBF and relative cerebral blood volume (rCBV) were negatively correlated with the ABCD3 score. ROC curve analysis identified a cutoff value of 0.8205 for rCBF, with a sensitivity of 84.10% and specificity of 58.10% for distinguishing the cerebral infarction group from the non-cerebral infarction group. Furthermore, rCBF ≤ 0.8205, degree of vascular stenosis, and ABCD3 score > 6 were identified as independent risk factors for secondary cerebral infarction in TIA patients within 90 days in TIA patients. The AUC of the WB-CTP-ABCD3 combined model for predicting secondary cerebral infarction within 90 days was 0.836. The model risk was assessed by plotting calibration curves. The value of p for the H-L goodness of fit test was 0.366 (p > 0.05), which indicated that the difference between the obtained model and the perfect model were statistically insignificant.ConclusionThe combined model of WB-CTP-ABCD3 shows promise as a valuable method for predicting secondary cerebral infarction within 90 days following TIA.

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“…Quantitative MRA has been shown to be useful in the assessment of a variety of flow-limiting cerebrovascular conditions [14][15][16][17][18][19][20][21][22] and has been validated as a primary tool to assess stroke risk in vertebrobasilar insufficiency. 23 To the best of our knowledge, our study is the first to report the use of QMRA in cerebral vasospasm after SAH.…”

Section: Discussionmentioning

confidence: 99%

Quantitative magnetic resonance angiography as an alternative imaging technique in the assessment of cerebral vasospasm after subarachnoid hemorrhage

et al. 2022

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Introduction The major mechanism of morbidity of delayed cerebral ischemia after subarachnoid hemorrhage (SAH) is considered to be severe vasospasm. Quantitative MRA (QMRA) provides direct measurements of vessel-specific volumetric blood flow and may permit a clinically relevant assessment of the risk of ischemia secondary to cerebral vasospasm. Purpose To evaluate the utility of QMRA as an alternative imaging technique for the assessment of cerebral vasospasm after SAH. Methods QMRA volumetric flow rates of the anterior cerebral artery (ACA), middle cerebral artery (MCA), and posterior cerebral artery (PCA) were compared with vessel diameters on catheter-based angiography. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of QMRA for detecting cerebral vasospasm was determined by receiver-operating characteristic curves. Spearman correlation coefficients were calculated for QMRA flow versus angiographic vessel diameter. Results Sixty-six vessels (10 patients) were evaluated with QMRA and catheter-based angiography. The median percent QMRA flow of all vessels with angiographic vasospasm (55.0%, IQR 34.3–71.6%) was significantly lower than the median percent QMRA flow of vessels without vasospasm (91.4%, IQR 81.4–100.4%) (p < 0.001). Angiographic vasospasm reduced QMRA-assessed flow by 23 ± 5 (p = 0.018), 95 ± 12 (p = 0.042), and 16 ± 4 mL/min (p = 0.153) in the ACA, MCA, and PCA, respectively, compared to vessels without angiographic vasospasm. The sensitivity, specificity, PPV, and NPV of QMRA for the discrimination of cerebral vasospasm was 84%, 72%, 84%, and 72%, respectively, for angiographic vasospasm >25% and 91%, 60%, 87%, and 69%, respectively, for angiographic vasospasm >50%. The Spearman correlation indicated a significant association between QMRA flows and vessel diameters ( rs = 0.71, p < 0.001). Conclusion Reduction in QMRA flow correlates with angiographic vessel narrowing and may be useful as a non-invasive imaging modality for the detection of cerebral vasospasm after SAH.

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Evaluation of Cerebral Blood Flow Dynamics in Transient Ischemic Attacks Patients with Fast Cine Phase Contrast Magnetic Resonance Angiography

Cited by 3 publications

References 10 publications

The evaluation value of intracranial magnetic resonance angiography combined with carotid ultrasound in cerebral infarction

The evaluation value of intracranial magnetic resonance angiography combined with carotid ultrasound in cerebral infarction

Predictive value of whole-brain CT perfusion combined with ABCD3 score for short-term secondary cerebral infarction after TIA

Quantitative magnetic resonance angiography as an alternative imaging technique in the assessment of cerebral vasospasm after subarachnoid hemorrhage

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