Evaluation of cerebral metabolism and quantitative electroencephalography after hypothermic circulatory, arrest and low-flow cardiopulmonary bypass at different temperatures

Mezrow, Craig K.; Midulla, Peter; Sadeghi, Ali; Gandsas, Alejandro; Wang, Weijia; Dapunt, O; Zappulla, Rosario A.; Griepp, Randall B.

doi:10.1016/s0022-5223(94)70375-2

Cited by 109 publications

(39 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Since glucose is also consumed with anaerobic glycolysis at a higher rate for ATP production compared with aerobic, it is unclear whether aerobic or anaerobic glycolysis might increase glucose consumption. It was reported that cerebral vascular resistance remained elevated and did not return to a baseline level until 8 hours after hypothermic circulatory arrest or low flow CPB [18]. Therefore, even after restart of CPB with rapid rewarming, regional or global anaerobic metabolism might remain, resulting from a relative lack of blood flow for the activation of metabolism.…”

Section: Discussionmentioning

confidence: 99%

Optimal brain temperature for retrograde cerebral perfusion in dogs

Satô¹,

Takahashi²,

Ishikawa³

et al. 1998

Int J Angiol

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Optimal brain temperature for retrograde cerebral perfusion in dogs

Satô¹,

Takahashi²,

Ishikawa³

et al. 1998

Int J Angiol

View full text Add to dashboard Cite

“…The temperature management is part of treatment of many patients with acute brain injury (Choi et al, 2012). Even without any brain pathology, hypothermia leads progressively to brain activity slowing and then suppression (Mezrow et al, 1994), (Stecker et al, 2001).…”

Section: Body Temperaturementioning

confidence: 99%

Clinical Use of EEG in the ICU

Alvarez

Rossetti²

2015

Journal of Clinical Neurophysiology

View full text Add to dashboard Cite

Neurophysiology is an essential tool for clinicians dealing with patients in the intensive care unit. Because of consciousness disorders, clinical examination is frequently limited. In this setting, neurophysiological examination provides valuable information about seizure detection, treatment guidance, and neurological outcome. However, to acquire reliable signals, some technical precautions need to be known. EEG is prone to artifacts, and the intensive care unit environment is rich in artifact sources (electrical devices including mechanical ventilation, dialysis, and sedative medications, and frequent noise, etc.). This review will discuss and summarize the current technical guidelines for EEG acquisition and also some practical pitfalls specific for the intensive care unit.

show abstract

“…Therapeutic hypothermia, on the other hand, is induced deliberately to protect vulnerable tissues from ischaemia-reperfusion injury. Lower temperature decreases tissue metabolism and oxygen demands (every 10°C alteration in temperature results in roughly a 50 per cent reduction in global and a 63 per cent reduction in cerebral metabolism) 66,67 , which can be helpful during periods of poor oxygen delivery (shock). As described in other reviews, hypothermia influences numerous biological process in the body 30,68 .…”

Section: Barriers To Translationmentioning

confidence: 99%

Translational barriers and opportunities for emergency preservation and resuscitation in severe injuries

Alam

2011

British Journal of Surgery

View full text Add to dashboard Cite

Background: Hypothermia is commonly used for organ and tissue preservation in multiple clinical settings, but its role in the management of injured patients remains controversial. There is no doubt that temperature modulation is a powerful tool, and hypothermia has been shown to protect cells during ischaemia and reperfusion, decrease organ damage and improve survival. Yet hypothermia is a double-edged sword: unless carefully managed, its induction can be associated with a number of complications.Methods: A literature review was performed to include important papers that address the impact of hypothermia on key biological processes, and explore the potential therapeutic role of hypothermia in trauma/haemorrhage models.

show abstract

Evaluation of cerebral metabolism and quantitative electroencephalography after hypothermic circulatory, arrest and low-flow cardiopulmonary bypass at different temperatures

Cited by 109 publications

References 7 publications

Optimal brain temperature for retrograde cerebral perfusion in dogs

Optimal brain temperature for retrograde cerebral perfusion in dogs

Clinical Use of EEG in the ICU

Translational barriers and opportunities for emergency preservation and resuscitation in severe injuries

Contact Info

Product

Resources

About