Evaluation of cervical cancer by computed tomography: Current status

Pannu, Harpreet K.; Fishman, Elliot K.

doi:10.1002/cncr.11684

Cited by 13 publications

(5 citation statements)

References 23 publications

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“…Using a modified technique called multidetector CT (MDCT), which consists of reducing slice thickness, improved spatial resolution, and creation of multiplanar and three-dimensional reconstructed images with improved anatomical details, 31 Tsili et al 32 retrospectively evaluated 22 patients with early-stage cervical cancer. In this study, patients were evaluated using MDCT scan and images were compared with pathology as the reference standard.…”

Section: Reviewmentioning

confidence: 99%

Measurement of tumor size in early cervical cancer: an ever-evolving paradigm

Salvo

Odetto

Perrotta

et al. 2020

Int J Gynecol Cancer

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The major tenets in accurately assessing tumor size in patients with early stage cervical cancer currently include physical examination, imaging studies, and pathologic evaluation. It is estimated that when comparing clinical stage based on physical examination and final pathology, the concordance diminishes as stage increases: 85.4%, 77.4%, 35.3%, and 20.5% for stage IB1, IB2, IIA, and IIB, respectively. Vaginal involvement and larger tumor diameter are considered the main causes of stage inaccuracy. When considering imaging studies, magnetic resonance imaging (MRI) provides the highest level of accuracy in the assessment of cervical tumor size. Its accuracy in determining tumor location within the cervix is approximately 91% and in predicting tumor size 93%. MRI imaging is also significantly more accurate in measuring tumor size, delineating cervical tumor boundaries, and local tumor extension when compared with computed tomography (CT) scan. When comparing with pelvic ultrasound, the accuracy of both imaging techniques (MRI and pelvic ultrasound) in the assessment of tumor size in small versus large tumors is comparable. Pertaining to pathology, the depth of invasion should be measured by convention from the nearest surface epithelium, which equates to tumor thickness. In the setting where tumor is found both in the conization and hysterectomy specimen, the horizontal extent should be measured by summing the maximum horizontal measurement in the different specimens and the depth of invasion measured as the maximum depth in either specimen. A new pattern-based classification for endocervical adenocarcinomas recommends the description of patterns of invasion for human papillomavirus (HPV)-related adenocarcinomas as this is associated with differing risks of lymph node involvement.

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Section: Reviewmentioning

confidence: 99%

Measurement of tumor size in early cervical cancer: an ever-evolving paradigm

Salvo

Odetto

Perrotta

et al. 2020

Int J Gynecol Cancer

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“…In certain instances, parametrial tumor extension may be seen on CT as soft tissue infiltration of the parametrial fat ( Fig. 5 ) ( Pannu and Fishman, 2003 ). However, parametrial extension is suboptimally visualized by CT.…”

Section: Us and Ct For Evaluation Of Extent Of Diseasementioning

confidence: 99%

Imaging and cancer of the cervix in low- and middle-income countries

Olpin

Chuang

Berek

et al. 2018

Gynecologic Oncology Reports

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Cervix cancer is the fourth most common cancer globally but the second most cancer in women in resource-limited countries. It has remained a clinically-staged neoplasm as per the International Federation of Gynecology and Obstetrics staging classification. As the imaging machines are becoming more available worldwide, the resource-stratified guidelines recommended the inclusion of imaging whenever possible to guide treatment planning. In this report, the utility of imaging in low- and middle-income countries for diagnosis and treatment of cancer of the cervix will be reviewed.

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“…When cervical cancer metastasis is suspected, CT is the radiographic study of choice [ 2 ]. Cervical cancer results in lung metastasis in 32-35% of autopsy findings [ 3 ].…”

Section: Discussionmentioning

confidence: 99%

Solitary Apical Lung Mass in a Patient With Cervical Cancer

2012

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We present the case of a 40 years old female presenting with a solitary apical lung mass, associated Horneŕ syndrome and evidence of medullary compression. Although she had a history of cervical cancer, a primary lung tumor was suspected. Tissue biopsy confirmed cervical cancer metastasis, highlighting the fact that although metastasis usually presents as multiple lung nodules, solitary lesions can be the presenting sign.

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Evaluation of cervical cancer by computed tomography: Current status

Cited by 13 publications

References 23 publications

Measurement of tumor size in early cervical cancer: an ever-evolving paradigm

Measurement of tumor size in early cervical cancer: an ever-evolving paradigm

Imaging and cancer of the cervix in low- and middle-income countries

Solitary Apical Lung Mass in a Patient With Cervical Cancer

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