Evaluation of Change in Microhardness by Application of MI Varnish on Primary Tooth Enamel, Affected by Use of Frequently Prescribed Paediatric Syrups: An In Vitro Study

Maurya, Ankita; Shashikiran, N D; Gaonkar, Namrata; Gugawad, Sachin; Taur, Swapnil; Hadakar, Savita; Chaudhari, Pradnya

doi:10.7759/cureus.6533

Cited by 6 publications

(6 citation statements)

References 13 publications

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“…(16) MI varnish containing CPP-ACP is a more stable and durable varnish and was found to be more effective in the reduction of Candida albicans count when compared with other fluoride varnishes Clinpro XT varnish, Fluor protector varnish, which was seen in compliance with the study conducted by Vinola Duraisamy et al (2015) (17) and Shweta Chandak et al (2016). (18) According to Salman et al (2019) (19) and Ankita Maurya et al (2020) (20) fluoride varnish containing CPP-ACP were found to have an increased acid resistance thus preventing the incidence of dental caries. This was in agreement with the current study.…”

Section: Discussionmentioning

confidence: 99%

Comparative Evaluation of Effect of Different Varnishes (MI Varnish, Clinpro Varnish and Fluor Protector Varnish) on Candida albicans Count and Salivary pH in Children aged 6-12 years – A Randomized Control Trial

JR¹,

Gupta²,

Gambhir³

et al. 2022

Journal of Pharmaceutical Negative Results

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PURPOSE: Candida albicans one of the commensal organisms in the oral cavity, causes fermentation of the dietary carbohydrates leading to the formation of organic acids, which contributes to the development of dental caries. The aim of the study was to evaluate and compare the efficacy of 3 different fluoride varnishes against Candida albicans in the prevention of dental caries before and immediately after fluoride varnish application and also over a period of 1 week, 1 month and 3 months. METHODOLOGY: A sample size of 60 children’s aged between 6-12 years were randomly selected by block randomization and divided into 3 groups: Group 1 MI Varnish, Group 2 Clinpro XT varnish and Group 3 Flour Protector varnish. Unstimulated saliva samples were collected before and after the application of fluoride varnishes (collected immediately after application, after 1 week, 1 month and 3 months) and were sent for microbiological analysis. The pH of the samples were evaluated by Indikrom paper strips. The results obtained were statistically analysed by mean, standard deviation and One way ANOVA. RESULTS: MI varnish showed a significant drop in Candida albicans followed by Clinpro XT varnish and Fluor Protector Varnish whereas no significant difference were seen in pH. CONCLUSION: The results of the study shows that MI Varnish, Clinpro XT Varnish and Fluor Protector Varnish have antifungal effect on Candida albicans. MI Varnish showed its more profound effect.

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Section: Discussionmentioning

confidence: 99%

Comparative Evaluation of Effect of Different Varnishes (MI Varnish, Clinpro Varnish and Fluor Protector Varnish) on Candida albicans Count and Salivary pH in Children aged 6-12 years – A Randomized Control Trial

JR¹,

Gupta²,

Gambhir³

et al. 2022

Journal of Pharmaceutical Negative Results

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“…Other factors like recurrent intakes (i.e., two or more times daily), sleep times, and after meals. Also, the reduced salivary flow may also promote increasing the risk of dental erosion (3,4) .…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the Erosive Effect of Pediatric Liquid Medicinal Syrups on Primary and Permanent Enamel

Mahmoud

ELmalt²,

Mohamed³

2022

ADJ-for Girls

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Purpose: To evaluate the erosive effect of pediatric liquid medicinal syrups on primary and permanent enamel. Materials and methods: Eighty primary and permanent teeth were equally divided into eight subgroups (n=10), according to the immersion solutions: Depakine, Ventolin, Sansovit, and Artificial saliva. The immersion cycles of the drugs were conducted under a 1-min agitation three times daily for 28 days. Enamel microhardness measurements were taken place at 0,7,14,21, and 28 days. The pH, titratable acidity, buffering capacity, and viscosity of the solutions were evaluated. A Scanning electron microscopy and statistical analysis of enamel microhardness measurements were assessed. Results: All the tested groups of the drugs had proven to produce significant demineralization of enamel after 28 days of exposure. At baseline, the permanent enamel showed higher mean enamel microhardness values than primary teeth. Generally with all the tested drugs, the primary teeth showed more decrease in enamel microhardness than permanent but without significance. The primary group (0-28days), the highest decrease of enamel microhardness was recorded in Sansovit group, then Ventolin, followed by Depakine group without significant change between the tested drugs, while in the permanent group, the highest decrease of enamel microhardness was recorded in Sansovit, then Depakine, followed by Ventolin group without significant change between the tested drugs. Kruskall Wallis test revealed a significant difference between tested drugs and control groups in both substrates. Conclusion: This study revealed that medicines used in the study could erode teeth even though the pH was above critical pH if it had high sugar content and viscosity. Sugar-free formulations have the ability to produce an erosive effect if they have low pH, high titratable acidity, high buffering capacity, and viscosity. This study showed that permanent teeth had higher mean enamel microhardness values than primary teeth, however no significant difference in the erosive potential of both types of teeth.

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“…[ 4 12 , 13 ] The severity of erosion was directly related to medicine exposure time. [ 13 14 ] Claritin™ syrup was considered in this study since it had the most erosive pattern among antihistamine-containing syrups. [ 12 ]…”

Section: Introductionmentioning

confidence: 99%

Effect of Zamzam Water on Microhardness of Primary Tooth Enamel After Erosion Induced by Claritin Syrup

Kufiyah

Bagasi

Nawlalili

et al. 2021

Journal of International Society of Preventive and Community Dentistry

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Evaluation of Change in Microhardness by Application of MI Varnish on Primary Tooth Enamel, Affected by Use of Frequently Prescribed Paediatric Syrups: An In Vitro Study

Abstract: Open Access Original Article

Cited by 6 publications

References 13 publications

Comparative Evaluation of Effect of Different Varnishes (MI Varnish, Clinpro Varnish and Fluor Protector Varnish) on Candida albicans Count and Salivary pH in Children aged 6-12 years – A Randomized Control Trial

Comparative Evaluation of Effect of Different Varnishes (MI Varnish, Clinpro Varnish and Fluor Protector Varnish) on Candida albicans Count and Salivary pH in Children aged 6-12 years – A Randomized Control Trial

Evaluation of the Erosive Effect of Pediatric Liquid Medicinal Syrups on Primary and Permanent Enamel

Effect of Zamzam Water on Microhardness of Primary Tooth Enamel After Erosion Induced by Claritin Syrup

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