Evaluation of choroidal thickness in non-alcoholic fatty liver disease

Abstract

We aimed to evaluate choroidal thickness with optical coherence tomography (OCT) in patients with non-alcoholic fatty liver disease (NAFLD). Twenty-five patients diagnosed with grade 2 NAFLD between the ages of 20 and 40 along with 20 age and sex-matched healthy controls were recruited. After full ophthalmological examination, choroidal thickness (CT) at fovea, nasal 500, nasal 1000, temporal 500 and temporal 1000-micron distances was obtained for both eyes using enhanced depth imaging (EDI)-OCT. Mean ages of NAFLD patients and healthy controls were 34.25±2.00 and 33.41±2.00 respectively. Statistical analysis showed that in the measurements taken from 1000-micron nasal to the left fovea, CT was 320.25±36.16 μm in NAFLD group and 298.05±36.90 μm in healthy group which showed a significant difference between two groups (p=0.046). No other measurements were statistically significant between groups (p > 0.05 for all measurements). In concussion, Choroidal thickness was not affected in grade 2 NAFLD.