Evaluation of choroidal thickness using enhanced depth imaging by spectral-domain optical coherence tomography in patients with pseudoexfoliation syndrome

Eroglu, Fatma Corak; Asena, Leyla; Şimşek, Cem; Kal, Alı; Yılmaz, Gökçe

doi:10.1038/eye.2015.34

Cited by 18 publications

(14 citation statements)

References 26 publications

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“…Choroidal thickness has been investigated in healthy individuals, patients with high myopia, polypoidal choroidal vasculopathy, age-related macular degeneration, central serous chorioretinopathy, glaucoma, pseudoexfoliation syndrome, sarcoid, tuberculosis-related granulomatous uveitis, and Behcet diseaserelated posterior uveitis. [8][9][10][11][12][13][14][15] Investigation of choroidal morphology in patients with scleroderma may help better understanding of choroidal involvement in patients with scleroderma. The aim of the present study was to investigate the choroidal thickness in patients with scleroderma and to compare them with healthy control subjects.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of choroidal thickness in patients with scleroderma

Coşkun

Zengin

Kenan

et al. 2016

Eye

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Purpose To investigate the choroidal thickness in patients with scleroderma and to compare them with healthy control subjects. Methods Forty-six patients with scleroderma (3 male and 43 female) and 31 healthy controls (6 male and 25 female) were included in the study. Twenty-five patients had limited-type and 21 patients had diffuse-type scleroderma. Only left eyes of the patients and control subjects were used in the analysis. Demographic features of all the patients and control subjects were recorded. Each subject underwent ophthalmological examinations including refraction, visual acuity, intraocular pressure, axial length (AXL) measurement, slit-lamp biomicroscopy, and fundus examination. Body mass index (BMI) was estimated for all participants. Results There were no significant differences between the patients with scleroderma and the control subjects in terms of age, gender, BMI, mean AXL, and mean spherical equivalent refractive error (SE) (P = 0.1, P = 0.086, P = 0.37, P = 0.55, and P = 0.072 respectively). The patients with scleroderma had significantly thinner nasal, temporal, and subfoveal choroid than the healthy control subjects (P 1 = 0.012, P 2 = 0.046, and P 3 o0.001, respectively). There were no significant differences between the patients with limited-type and diffuse-type scleroderma in terms of age, gender, BMI, mean AXL, mean SE, nasal, temporal, and subfoveal choroidal thicknesses (all P40.05). Conclusions Choroidal thickness in patients with scleroderma was significantly less than healthy control subjects. Vasculopathy in scleroderma is characterized by obliteration of arterioles and reduced capillary density may cause atrophy of choroid in patients with scleroderma.

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Section: Introductionmentioning

confidence: 99%

Evaluation of choroidal thickness in patients with scleroderma

Coşkun

Zengin

Kenan

et al. 2016

Eye

View full text Add to dashboard Cite

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“…Literatürde koroid kalınlık öl-çümünün farklı cihazlar ile yapıldığı birçok ça-lışma mevcuttur. 9,[16][17][18][20][21][22] Branchini ve ark., koroid kalınlık ölçümünün farklı cihazlar ile tekrarlanabilir olduğunu göstermişlerdir. 26 Göktaş ve ark., PEX sendromlu hastalarda kontrol grubuna göre koroid kalınlığında incelme saptamış, bunun azalmış oküler kan akımına ve artmış vasküler rezistansa bağlı olabileceğini savunmuşlardır.…”

Section: Gereç Ve Yöntemlerunclassified

“…ise PEX materyali saptanan ve klinik olarak etkilenmiş gözlerde, etkilenmemiş göz ve kontrol grubuna göre koroidde anlamlı incelme bulmuşlardır. 18 PEX materyalinin klinik olarak gözü etkilemesini takiben, koroid kan akımının etkilediğini savunmuşlardır. 18 Zengin ve ark.…”

Section: Gereç Ve Yöntemlerunclassified

“…18 PEX materyalinin klinik olarak gözü etkilemesini takiben, koroid kan akımının etkilediğini savunmuşlardır. 18 Zengin ve ark. ise PEX sendromlu hastalar ile kontrol grubu arasında koroid kalınlığı açısından fark saptamamışlardır.…”

Section: Gereç Ve Yöntemlerunclassified

“…[10][11][12] Literatürde çalışmalar olmakla birlikte, psödoeksfo-liatif materyalin koroid kan akımı ve koroid kalınlığına etkisi tartışmalıdır. 5,6,[13][14][15][16][17][18][19][20][21][22] Bu çalışmada, PEX sendromlu hastalarda ve sağlıklı bireylerde makuler koroid kalınlığının değerlendirilip sağlıklı gözlerle karşılaştırılması amaçlanmıştır.…”

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