Evaluation of chronic cough in chemical chronic bronchitis patients

Ghanei, Mostafa; Hosseini, Alireza; Arabbaferani, Zohre; Shahkarami, Efat

doi:10.1016/j.etap.2004.09.006

Cited by 18 publications

(16 citation statements)

References 17 publications

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“…6,20 These symptoms persist and even get worse over the years in severe cases despite continuous medical care as indicated in recent reports. 12,19,21 The main objective clinical findings of the lower respiratory tract in our patients including generalized wheezing (the most common sign), rhonchi and crackles are in agreement with the previous reports. 12,19,21 Pulmonary function testing has revealed more obstructive patterns than restriction.…”

Section: Lower Respiratory Complicationssupporting

confidence: 93%

“…12,19,21 The main objective clinical findings of the lower respiratory tract in our patients including generalized wheezing (the most common sign), rhonchi and crackles are in agreement with the previous reports. 12,19,21 Pulmonary function testing has revealed more obstructive patterns than restriction. It was initially believed that due to lung fibrosis, obstructive pattern will change over the years to restrictive pattern, 6,16 but further investigations revealed that lung fibrosis is not a common complication of sulfur mustard poisoning.…”

Section: Lower Respiratory Complicationssupporting

confidence: 93%

“…6,16,17 However, hypoxemia and hypercapnea are commonly observed in moderateto-severe cases, leading from asthmatic bronchitis to COPD, core pulmonale and respiratory failure in the final stages of the disease. 18,19,21 COPD was found the most common lower respiratory complication in our patients, which was much higher than the previous study on these patients. 21 Infection of the respiratory tract results in bronchopneumonia at the early stage but later in the course induces bronchiectasis as was diagnosed in this study and reported earlier.…”

Section: Lower Respiratory Complicationscontrasting

confidence: 75%

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Delayed toxic effects of sulfur mustard on respiratory tract of Iranian veterans

et al. 2010

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To investigate late toxic effects of sulfur mustard (SM) on the upper and lower respiratory tracts of Iranian veterans, 43 male veterans with more than 25% disability due to SM poisoning in 20−25 years after exposure, were studied. Direct laryngoscopy, pulmonary function tests, arterial blood gasses and pH, computed tomography of sinuses and lungs were investigated. The patients were aged 50.6 (8.9 SD) years with body mass index (BMI) of 26.6 (4.0) and disability of 53.2 (17.0%). The common findings of the upper respiratory tract were dysphonia (79.1%), post-nasal discharge (PND; 41.9%), lower larynx position (30.2%), limitation of vocal cords (25.6%) and mucosal inflammation of larynx (14.8%). The common lower respiratory diseases were diagnosed as chronic obstructive respiratory disease (84%), bronchiectasis (44.1%) and lung fibrosis (7.7%). Severity of disability was negatively correlated with BMI ( p = 0.032), spirometric parameters ( p < 0.001) and oxygen saturation ( p < 0.001), but positively correlated with low-density lipoproteins (LDL <0.010), blood pressure ( p = 0.008), diabetes mellitus ( p < 0.001), wheezing ( p = 0.0043) and bronchiectasis ( p < 0.001). Delayed toxic effects of SM in upper and lower respiratory tracts were mostly inflammatory and infectious complications, SM-induced disabilities were significantly correlated with risk factors such as diabetes mellitus, hypertension, LDL and lower-respiratory complications.

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Section: Lower Respiratory Complicationssupporting

confidence: 93%

Section: Lower Respiratory Complicationssupporting

confidence: 93%

Section: Lower Respiratory Complicationscontrasting

confidence: 75%

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Delayed toxic effects of sulfur mustard on respiratory tract of Iranian veterans

et al. 2010

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“…Virtually all patients presented with acid-reXux related laryngopharyngitis. There had been no clear precedent in other reported inhalation injury case series until the recent reports by Ghanei et al (2005Ghanei et al ( , 2006. GERD and airway and pulmonary disease (Ruigómez et al 2005;Kempainen et al 2007) have an unclear, probably bidirectional association, and it is notable that GERD and LAD were similarly associated with early arrival at the WTC site.…”

Section: Discussionmentioning

confidence: 89%

Occupational toxicant inhalation injury: the World Trade Center (WTC) experience

Hoz

Shohet

Chasan

et al. 2007

Int Arch Occup Environ Health

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Occupational exposures at the WTC remain consistently associated with a disease profile, which includes five major diagnostic categories. These conditions often coexist in different combinations, which (as expected) mutually enhances their clinical expression, complicates medical management, and slows recovery. Cigarette smoking and early arrival at the WTC site appear to be risk factors for lower airway disease diagnosis.

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“…On physical examination, crackles, wheezing, and rhonchi depending to the state of the patient, can be seen (12,29).The attacks of COPD exacerbation with increasing the severity of dyspnea, cough, and discoloration of sputum, is a common clinical presentation (12,30).…”

Section: Clinical Manifestationsmentioning

confidence: 99%