Evaluation of clinical benefits achievable by using different optimization algorithms during real-time prostate brachytherapy

Adamczyk, M.; Zwierzchowski, Grzegorz; Malicki, Julian; Skowronek, Janusz

doi:10.1016/j.ejmp.2011.12.005

Cited by 8 publications

(4 citation statements)

References 30 publications

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“…The number of treatment fractions was 10 for palliative cases and ranging between 20 and 39 for radical cases at the LRCP, while all patients at the GPCC had 25 fractions of external beam radiotherapy followed by a brachytherapy boost. [31][32][33] The database included the following information for each patient: (i) the number of treatment fractions; (ii) daily correction shifts in the x, y, and z directions and their manual correction components; (iii) treatment position (supine or prone); (iv) the target for irradiation (prostate or prostate bed), and (v) MVCT imaging mode (normal or coarse).…”

Section: Methodsmentioning

confidence: 99%

Comparative analysis of image guidance in two institutions for prostate cancer patients

Piotrowski

Yartsev

Rodrigues

et al. 2014

Reports of Practical Oncology & Radiotherapy

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Section: Methodsmentioning

confidence: 99%

Comparative analysis of image guidance in two institutions for prostate cancer patients

Piotrowski

Yartsev

Rodrigues

et al. 2014

Reports of Practical Oncology & Radiotherapy

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“…Jednak jedną z dobrze znanych wad algorytmów obliczeniowych jest to, że takie obliczenia dawki opierają się na jednej pozycji źródłowej w jednorodnym środowisku wodnym [4,5]. Całkowity rozkład dawki w ośrodku jest produktem sumy rozkładu dawki pochodzącej od każdej pozycji źródła, które są obliczane przez algorytm optymalizacyjny [6,7].…”

Section: Nowe Algorytmy Do Obliczania Rozkładów Dawek W Brachyterapiiunclassified

Zastosowanie filmów radiochromowych w weryfikacji rozkładów dawek w brachyterapii. Przygotowanie do wprowadzenia algorytmów zaproponowanych przez TG-186 AAPM.

Bielęda

2017

los

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StreszczenieWeryfikacja rozkładów dawki w brachyterapii stawia przed fizykami medycznymi wiele wyzwań. Ze względu na wysoki gradient dawki pomiary wymagają bardzo dużej higieny pracy oraz wysokiej dokładności. Do tej pory stosowane były algorytmy do obliczenia rozkładów dawek zaimplementowane w systemach planowania leczenia wprowadzone przez TG-43 AAPM (ang. Task Group 43 of American Association of Physicists in Medicine -Grupa Zadaniowa Amerykańskiego Towarzystwa Fizyki Medycznej). Charakteryzują się one przede wszystkim tym, że przyrównują współczynniki osłabienia promieniowania ośrodka, w którym rozchodzi się promieniowanie do współczynnika osłabienia promieniowania wody. Taka sama procedura jest zastosowana dla ośrodka, w którym obliczana jest dawka pochłonięta. Wprowadzenie przez grupę TG-186 AAPM nowych algorytmów obliczających rozkłady dawek, uwzględniających rzeczywiste współczynniki osłabienia i pochłaniania promieniowania wymagają bardziej szczegółowych i dokładnych procedur kontroli jakości przygotowanych planów leczenia w brachyterapii. W niniejszej pracy omówiono najnowsze doniesienia dotyczące weryfikacji rozkładów dawek w brachyterapii z uwzględnieniem doniesień przedstawionych w trakcie konferencji naukowej 3rd ESTRO Forum, która odbyła się w 2015 roku w Barcelonie. AbstractVerification of brachytherapy dose distributions is a challenging task for medical physicists. Due to a very steep dose gradient, measurements require a very high hygiene and accuracy. Until now, the algorithms introduced by the task group TG-43 of AAPM (American Association of Physicists in Medicine have been used to calculate the dose distributions implemented in the treatment planning systems). These algorithm Adres do korespondencji

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“…The TPS used in most of the cases are still based on the TG-43 recommendations, which have been verified in homogenous conditions [ 4 ]. However, one of the well-known defects of the calculation algorithms based on the Sivert integral and modular dose calculation models is that such dose rate calculations are based on a single source position in a homogenous water environment [ 5 , 6 , 7 ], whereas the overall dose distribution in the medium is a product of the contribution from each source position and the modulated step time, which are governed by optimization routines [ 8 , 9 ].…”

Section: Purposementioning

confidence: 99%

Film based verification of calculation algorithms used for brachytherapy planning-getting ready for upcoming challenges of MBDCA

Zwierzchowski

Bielęda

Skowronek

et al. 2016

jcb

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PurposeWell-known defect of TG-43 based algorithms used in brachytherapy is a lack of information about interaction cross-sections, which are determined not only by electron density but also by atomic number. TG-186 recommendations with using of MBDCA (model-based dose calculation algorithm), accurate tissues segmentation, and the structure's elemental composition continue to create difficulties in brachytherapy dosimetry. For the clinical use of new algorithms, it is necessary to introduce reliable and repeatable methods of treatment planning systems (TPS) verification. The aim of this study is the verification of calculation algorithm used in TPS for shielded vaginal applicators as well as developing verification procedures for current and further use, based on the film dosimetry method.Material and methodsCalibration data was collected by separately irradiating 14 sheets of Gafchromic® EBT films with the doses from 0.25 Gy to 8.0 Gy using HDR 192Ir source. Standard vaginal cylinders of three diameters were used in the water phantom. Measurements were performed without any shields and with three shields combination. Gamma analyses were performed using the VeriSoft® package.ResultsCalibration curve was determined as third-degree polynomial type. For all used diameters of unshielded cylinder and for all shields combinations, Gamma analysis were performed and showed that over 90% of analyzed points meets Gamma criteria (3%, 3 mm).ConclusionsGamma analysis showed good agreement between dose distributions calculated using TPS and measured by Gafchromic films, thus showing the viability of using film dosimetry in brachytherapy.

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Evaluation of clinical benefits achievable by using different optimization algorithms during real-time prostate brachytherapy

Abstract: Application of the blind inverse optimization (BIO) algorithm led to clinically best dose parameters for PTV and the rectum. Use of geometrical optimization (GO) led to smaller doses in the urethra, which was however associated with a certain dose decrease also in PTV.

Cited by 8 publications

References 30 publications

Comparative analysis of image guidance in two institutions for prostate cancer patients

Comparative analysis of image guidance in two institutions for prostate cancer patients

Zastosowanie filmów radiochromowych w weryfikacji rozkładów dawek w brachyterapii. Przygotowanie do wprowadzenia algorytmów zaproponowanych przez TG-186 AAPM.

Film based verification of calculation algorithms used for brachytherapy planning-getting ready for upcoming challenges of MBDCA

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